Page last updated: 2024-11-12
motilin, nle(13)-
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
motilin, Nle(13)-: linear analog of motilin; increase gastric motility & pepsin output; synthetic [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
ID Source | ID |
---|---|
PubMed CID | 16143638 |
CHEMBL ID | 526863 |
MeSH ID | M0052740 |
Synonyms (7)
Synonym |
---|
CHEMBL526863 |
motilin, nle(13)- |
13-nle-motilin |
55524-56-6 |
motilin (pig), 13-l-norleucine- |
motilin, norleucine(13)- |
13-norleucine-motilin |
Research Excerpts
Pharmacokinetics
Excerpt | Reference | Relevance |
---|---|---|
"The study provides pharmacokinetic data for exogenous synthetic and endogenous natural motilin in man." | ( Pharmacokinetics of motilin in man. Bloom, SR; Demling, L; Domschke, S; Domschke, W; Mitznegg, P; Wuensch, E, 1977) | 0.26 |
Dosage Studied
Excerpt | Relevance | Reference |
---|---|---|
" 13-nle-motilin increased intraluminal pressure in the pylorus and duodenum, and dose-response analysis showed the duodenum to be twice as sensitive as the pylorus to the polypeptide." | ( Effects of 13-nle-motilin on the electrical and mechanical activity of the isolated perfused canine stomach and duodenum. Demling, L; Domschke, W; Green, WE; Ritchie, HD; Ruppin, H; Wingate, DL; Wünsch, DE, 1976) | 0.26 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Bioassays (5)
Research
Studies (13)
Timeframe | Studies, This Drug (%) | All Drugs % |
---|---|---|
pre-1990 | 7 (53.85) | 18.7374 |
1990's | 3 (23.08) | 18.2507 |
2000's | 3 (23.08) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 11.60
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (11.60) All Compounds (24.57) |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
---|---|---|
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 13 (100.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |