Mono(2-methoxyethyl) phthalate (MEHP) is a plasticizer commonly used in polyvinyl chloride (PVC) products. It is often found in food packaging, medical devices, and toys. MEHP is a metabolite of di(2-methoxyethyl) phthalate (DEHP), which is a widely used plasticizer. DEHP is converted to MEHP in the body during digestion. MEHP has been shown to have endocrine disrupting effects, particularly on the reproductive system. It is also a potential carcinogen. Because of its widespread use and potential health effects, MEHP has been the subject of numerous studies. Researchers are investigating its environmental fate, toxicity, and potential for human exposure.'
mono(2-methoxyethyl) phthalate: metabolite of dimethoxyethyl phthalate [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 85462 |
| SCHEMBL ID | 186286 |
| MeSH ID | M0122150 |
| Synonym |
|---|
| monomethoxyethyl phthalate |
| usaf ke-3 |
| phthalic acid, methoxyethyl ester |
| phthalic acid, mono(2-methoxyethyl) ester |
| methoxyethyl phthalate |
| mono(2-methoxyethyl) phthalate |
| 1,2-benzenedicarboxylic acid, mono(2-methoxyethyl) ester |
| phthalic acid, monomethoxyethyl ester |
| brn 3293107 |
| 2-(2-methoxyethoxycarbonyl)benzoic acid |
| phthalic acid mono(2-methoxyethyl) ester |
| 1,2-benzenedicarboxylic acid, 1-(2-methoxyethyl) ester |
| 3-09-00-04172 (beilstein handbook reference) |
| 16501-01-2 |
| SCHEMBL186286 |
| 2-methoxyethyl hydrogen phthalate |
| phthalic acid, mono-2-methoxyethyl ester |
| NGFWAKGWMSOVMP-UHFFFAOYSA-N |
| 2-((2-methoxyethoxy)carbonyl)benzoic acid |
| mono-2-methoxyethyl phthalate |
| E77564 |
| DTXSID90884912 |
| AS-80491 |
| Excerpt | Reference | Relevance |
|---|---|---|
| " While xenoestrogenic and chronic toxic effects of phthalates have been extensively discussed, there is little data on genotoxic effects in human cells." | ( Mono(2-ethylhexyl)phthalate exhibits genotoxic effects in human lymphocytes and mucosal cells of the upper aerodigestive tract in the comet assay. Harréus, UA; Kastenbauer, ER; Kleinsasser, NH; Rettenmeier, AW; Sassen, AW; Staudenmaier, R; Wallner, BC, 2004) | 0.32 |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.36) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||