Compounds > microcin sf608
Page last updated: 2024-11-12

microcin sf608

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

microcin SF608: Choi = 2-carboxy-6-hydroxyoctahydroindole; Hpla = alpha-hydroxy acid p-hydroxyphenyllactic acid; Agma = agmatine, the decarboxylated arginine; from nontoxic strain of cyanobacterium, Microcystis aeruginosa; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID10793809
CHEMBL ID2386692
SCHEMBL ID1371098
MeSH IDM0444439

Synonyms (5)

Synonym
CHEMBL2386692 ,
SCHEMBL1371098
(2s,3as,6r,7as)-n-[4-(diaminomethylideneamino)butyl]-6-hydroxy-1-[(2s)-2-[[(2s)-2-hydroxy-3-(4-hydroxyphenyl)propanoyl]amino]-3-phenylpropanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxamide
bdbm50491950
microcin sf608
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (2)

Assay IDTitleYearJournalArticle
AID751253Inhibition of trypsin (unknown origin)2013Journal of natural products, Jun-28, Volume: 76, Issue:6
Aeruginosins from a Microcystis sp. bloom material collected in Varanasi, India.
AID1056590Inhibition of trypsin (unknown origin) using benzoyl-L-arginine-p-nitroanilide hydrochloride as substrate preincubated for 5 mins before substrate addition measured after 30 mins2013Journal of natural products, Dec-27, Volume: 76, Issue:12
Protease inhibitors from Microcystis aeruginosa bloom material collected from the Dalton Reservoir, Israel.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.84

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.84 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.63 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.84)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
leucine
Leucine: An essential branched-chain amino acid important for hemoglobin formation.. leucine : A branched-chain amino acid that consists of glycine in which one of the hydrogens attached to the alpha-carbon is substituted by an isobutyl group.		2.0110amino acid zwitterion;
L-alpha-amino acid;
leucine;
proteinogenic amino acid;
pyruvate family amino acid		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
n-heptane
Heptanes: Seven-carbon alkanes with the formula C7H16.. heptane : A straight-chain alkane with seven carbon atoms. It has been found in Jeffrey pine (Pinus jeffreyi).		2.0510alkane;
volatile organic compound		non-polar solvent;
plant metabolite
aeruginosin 298-a
aeruginosin 298-A: structure in first source		2.0110
cyanopeptolin s
cyanopeptolin S: a sulfated, cyclic depsipeptide; from a water bloom of Microsystis sp.; structure given in first source		2.0810
ConditionIndicatedRelationship StrengthStudiesTrials