Compounds > methylenolactocin
Page last updated: 2024-11-07

methylenolactocin

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

methylenolactocin: from Penicillium sp.; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID133968
MeSH IDM0159213

Synonyms (12)

Synonym
3-carboxy-2-methylene-4-nonanolide
3-furancarboxylic acid, tetrahydro-4-methylene-5-oxo-2-pentyl-, trans-(-)-
unii-6a2exc8cnc
6a2exc8cnc ,
112923-53-2
methylenolactocin
(2s,3r)-4-methylidene-5-oxo-2-pentyloxolane-3-carboxylic acid
DTXSID40920955
(2s,3r)-tetrahydro-4-methylene-5-oxo-2-pentyl-3-furancarboxylic acid
3-furancarboxylic acid, tetrahydro-4-methylene-5-oxo-2-pentyl-, (2s-trans)-
(-)-methylenolactomycin
methylenolactomycin

Research Excerpts

Effects

ExcerptReferenceRelevance
"Methylenolactocin has the molecular formula of C11H16O4 and possess an exomethylene lactone structure."( Methylenolactocin, a novel antitumor antibiotic from Penicillium sp.
Hirota, A; Nakagawa, M; Nakayama, M; Park, BK, 1988)		2.44
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (20.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.53

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.53 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.32 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.53)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
4-butyrolactone
4-Butyrolactone: One of the FURANS with a carbonyl thereby forming a cyclic lactone. It is an endogenous compound made from gamma-aminobutyrate and is the precursor of gamma-hydroxybutyrate. It is also used as a pharmacological agent and solvent.. tetrahydrofuranone : Any oxolane having an oxo- substituent at any position on the tetrahydrofuran ring.. gamma-butyrolactone : A butan-4-olide that is tetrahydrofuran substituted by an oxo group at position 2.		3.0240butan-4-olidemetabolite;
neurotoxin
chromium
Chromium: A trace element that plays a role in glucose metabolism. It has the atomic symbol Cr, atomic number 24, and atomic weight 52. According to the Fourth Annual Report on Carcinogens (NTP85-002,1985), chromium and some of its compounds have been listed as known carcinogens.. chromium ion : An chromium atom having a net electric charge.. chromium atom : A chromium group element atom that has atomic number 24.		2.4920chromium group element atom;
metal allergen		micronutrient
alkenes
[no description available]		2.110
protolichesterinic acid
protolichesterinic acid: HIV-1 reverse transcriptase inhibitor; isolated from the lichen Cetraria islandica; RN given refers to (2R-trans)-isomer; structure in first source		7.5220
alpha-methylene gamma-butyrolactone
alpha-methylene gamma-butyrolactone : A butan-4-olide having a methylene group at the 3-position.		2.4920butan-4-olideanti-ulcer drug;
gastrointestinal drug
lignans
Lignans: A class of dibenzylbutane derivatives which occurs in higher plants and in fluids (bile, serum, urine, etc.) in man and other animals. These compounds, which have a potential anti-cancer role, can be synthesized in vitro by human fecal flora. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)		2.0610
hydroxymatairesinol
hydroxymatairesinol: a plant lignan from Norway spruce (Picea abies); structure in first source		2.0610
nephrosteranic acid
nephrosteranic acid: structure in first source		2.1510gamma-lactone
ConditionIndicatedRelationship StrengthStudiesTrials