Page last updated: 2024-12-07
methyl 5-nitro-2-furoate
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 94882 |
| CHEMBL ID | 120921 |
| CHEBI ID | 189109 |
| SCHEMBL ID | 1350315 |
| MeSH ID | M0110529 |
Synonyms (51)
| Synonym |
|---|
| 1874-23-3 |
| nsc-6457 |
| nsc6457 |
| 2-furancarboxylic acid, 5-nitro-, methyl ester |
| 5-nitro-2-furoic acid methyl ester |
| methyl 5-nitropyromucate |
| brn 0165132 |
| methyl 5-nitrofuroate |
| 2-furoic acid, 5-nitro-, methyl ester |
| nsc 6457 |
| ai3-23607 |
| ccris 2152 |
| methyl nitrofuroate |
| methyl 5-nitro-2-furancarboxylate |
| methyl 5-nitro-2-furoate |
| 5-nitro-2-furancarboxylic acid methyl ester |
| STK448639 |
| methyl 5-nitrofuran-2-carboxylate |
| methyl 5-nitro-2-furoate, 98% |
| SR-01000640475-1 |
| AKOS003309694 |
| CHEMBL120921 |
| methyl 5-nitrouran-2-carboxylate |
| CHEBI:189109 |
| EN300-49149 |
| A813151 |
| 71qm4e6j90 , |
| unii-71qm4e6j90 |
| CCG-51159 |
| GEO-01894 |
| FT-0628326 |
| 5-nitro-2-(methoxycarbonyl)furan |
| methyl 5'-nitropyromucate |
| methyl 5-nitro-2-furylcarboxylate |
| SCHEMBL1350315 |
| 8P-568S |
| methyl 5 nitrofuran-2-carboxylate |
| methyl-5-nitrofuran-2-carboxylate |
| methyl-5-nitro-2-furoate |
| W-200187 |
| DTXSID50172049 |
| F8880-1591 |
| mfcd00051956 |
| Z19638744 |
| CS-0048963 |
| AM10047 |
| SB13378 |
| Q27265985 |
| 5-nitro-2-furan-carboxylic acid, methyl ester |
| methyl5-nitrofuran-2-carboxylate |
| SY041932 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Drug Classes (1)
| Class | Description |
|---|---|
| carboxylic ester | An ester of a carboxylic acid, R(1)C(=O)OR(2), where R(1) = H or organyl and R(2) = organyl. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
Bioassays (10)
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID1794808 | Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL). | 2014 | Journal of biomolecular screening, Jul, Volume: 19, Issue:6 | A High-Throughput Assay to Identify Inhibitors of the Apicoplast DNA Polymerase from Plasmodium falciparum. |
| AID1794808 | Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL). | |||
| AID1159607 | Screen for inhibitors of RMI FANCM (MM2) intereaction | 2016 | Journal of biomolecular screening, Jul, Volume: 21, Issue:6 | A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway. |
| AID723483 | Cytotoxicity against human HeLa cells after 65 hrs by Alamar blue assay | 2013 | Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3 | A class of 5-nitro-2-furancarboxylamides with potent trypanocidal activity against Trypanosoma brucei in vitro. |
| AID106021 | Tested for cytotoxicity towards human MRC-5 cells | 2002 | Bioorganic & medicinal chemistry letters, Dec-16, Volume: 12, Issue:24 | Antitrypanosomal activities and cytotoxicity of 5-nitro-2-furancarbohydrazides. |
| AID213632 | Evaluated in vitro for antitrypanosomal activity against Trypanosoma cruzi | 2002 | Bioorganic & medicinal chemistry letters, Dec-16, Volume: 12, Issue:24 | Antitrypanosomal activities and cytotoxicity of 5-nitro-2-furancarbohydrazides. |
| AID100887 | Evaluated in vitro for antitrypanosomal activity against Leishmania infantum | 2002 | Bioorganic & medicinal chemistry letters, Dec-16, Volume: 12, Issue:24 | Antitrypanosomal activities and cytotoxicity of 5-nitro-2-furancarbohydrazides. |
| AID723484 | Trypanocidal activity against bloodstream form of Trypanosoma brucei brucei 427 after 72 hrs by Alamar blue assay | 2013 | Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3 | A class of 5-nitro-2-furancarboxylamides with potent trypanocidal activity against Trypanosoma brucei in vitro. |
| AID140480 | Tested for cytotoxicity towards mouse peritoneal macrophages (MPM) | 2002 | Bioorganic & medicinal chemistry letters, Dec-16, Volume: 12, Issue:24 | Antitrypanosomal activities and cytotoxicity of 5-nitro-2-furancarbohydrazides. |
| AID215328 | Evaluated in vitro for antitrypanosomal activity against Trypanosoma brucei | 2002 | Bioorganic & medicinal chemistry letters, Dec-16, Volume: 12, Issue:24 | Antitrypanosomal activities and cytotoxicity of 5-nitro-2-furancarbohydrazides. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
Research
Studies (7)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 12.72
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.72) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 7 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||