Compounds > methyl 4-toluene sulfonate
Page last updated: 2024-12-05

methyl 4-toluene sulfonate

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

methyl 4-toluene sulfonate: catalyst in dental impression; material Scutan causing contact dermatitis; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID6645
CHEMBL ID5189891
SCHEMBL ID27524
MeSH IDM0062362

Synonyms (94)

Synonym
methyl 4-methylbenzene-1-sulfonate
EN300-15726
benzenesulfonic acid, 4-methyl-, methyl ester
p-methylbenzenesulfonate methyl ester
methyl tosylate
methyl 4-methylbenzenesulfonate
p-toluenesulfonic acid, methyl ester
methylester kyseliny p-toluensulfonove
p-toluenesulfonic acid methyl ester
wln: 1oswr d1
methyl-p-toluenesulfonate
nsc-406335
methyl p-toluenesulfonate
methyl toluenesulfonate
nsc406335
methyl p-tosylate
p-toluolsulfonsaeure methyl ester
80-48-8
methyl toluene-4-sulfonate
ortho-toluenesulfonic acid, methyl ester
methyl p-toluenesulfonate, 98%
ccris 9151
hsdb 2025
brn 0609209
methyl 4-toluene sulfonate
methylester kyseliny p-toluensulfonove [czech]
ai3-02550
methyl toluene-4-sulphonate
einecs 201-283-5
4-toluenesulfonic acid, methyl ester
nsc 406335
p-toluolsulfonsaeure methyl ester [german]
methyl p-methylbenzenesulfonate
methyl toluene sulfonate
FT-0695834
T0269
A839928
4-methyl-benzenesulfonic acid methyl ester
AM804364
methyl 4-toluenesulfonate
AKOS008938769
4su69ki68l ,
unii-4su69ki68l
4-11-00-00247 (beilstein handbook reference)
FT-0619531
methyl 4-methylbenzenesulphonate
methyl-p-toluensulfonate
methyl para-toluenesulphonate
paratoluen sulphonate methyl ester
methyl-paratoluene sulphonate
methyl rho-toluenesulfonate
methyl para-toluene sulfonate
methyl para-toluenesulfonate
methyltosylate
tsome
methyl-4-methylbenzenesulfonate
methyl-p-toluenesulphonate
tosylate methyl ester
p-toluene sulfonic acid methyl ester
methyl p-toluene-sulfonate
methyl tosylat
methyl p-toluene sulphonate
methyl paratoluenesulfonate
methyl p-toluenesulphonate
meots
methyl-4-toluene sulphonate
toluene-4-sulfonic acid-methyl ester
p-toluene-sulphonic acid methyl ester
SCHEMBL27524
methyl 4-toluene sulfonate [hsdb]
p-methylbenzenesulfonic acid methyl ester
toluene-4-sulfonic acid methyl ester
NCGC00357078-01
cas-80-48-8
dtxcid1031123
dtxsid4052550 ,
tox21_303790
Q-200515
STR01542
methyl ester of 4-methylbenzenesulfonic acid
methyl-(4)-toluenesulfonate
F0001-2085
methyl p-toluenesulfonate, purum, >=97.0% (gc)
mfcd00008417
CHEMBL5189891
tosome
CS-0015899
Q25616437
methyl-4-toluene sulfonate
mfcd00069406
D72514
methyl-d3 4-methylbenzenesulfonate
SY276580
methyl-13c,d3toluenesulfonate
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Protein Targets (1)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
GLI family zinc finger 3Homo sapiens (human)Potency6.85900.000714.592883.7951AID1259369
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (1)

Assay IDTitleYearJournalArticle
AID1852941Inhibition of human PHPT1 expressed in Escherichia coli BL21 (DE3) using pNPP as substrate at 25 uM incubated for 1 hr by multimode microplate reader analysis2022ACS medicinal chemistry letters, Dec-08, Volume: 13, Issue:12
Identification of a Target Site for Covalent Inhibition of Protein Phosphohistidine Phosphatase 1.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (10)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (10.00)18.7374
1990's0 (0.00)18.2507
2000's2 (20.00)29.6817
2010's4 (40.00)24.3611
2020's3 (30.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.40

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.40 (24.57)
Research Supply Index2.40 (2.92)
Research Growth Index4.80 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.40)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other10 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
ammonium hydroxide
azane : Saturated acyclic nitrogen hydrides having the general formula NnHn+2.		2.1110azane;
gas molecular entity;
mononuclear parent hydride		EC 3.5.1.4 (amidase) inhibitor;
metabolite;
mouse metabolite;
neurotoxin;
NMR chemical shift reference compound;
nucleophilic reagent;
refrigerant
methanol
Methanol: A colorless, flammable liquid used in the manufacture of FORMALDEHYDE and ACETIC ACID, in chemical synthesis, antifreeze, and as a solvent. Ingestion of methanol is toxic and may cause blindness.. primary alcohol : A primary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.. methanol : The primary alcohol that is the simplest aliphatic alcohol, comprising a methyl and an alcohol group.		2.0210alkyl alcohol;
one-carbon compound;
primary alcohol;
volatile organic compound		amphiprotic solvent;
Escherichia coli metabolite;
fuel;
human metabolite;
mouse metabolite;
Mycoplasma genitalium metabolite
nickel
Nickel: A trace element with the atomic symbol Ni, atomic number 28, and atomic weight 58.69. It is a cofactor of the enzyme UREASE.. nickel ion : A nickel atom having a net electric charge.. nickel atom : Chemical element (nickel group element atom) with atomic number 28.		2.110metal allergen;
nickel group element atom		epitope;
micronutrient
ethacrynic acid
Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.. etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.		2.4110aromatic ether;
aromatic ketone;
dichlorobenzene;
monocarboxylic acid		EC 2.5.1.18 (glutathione transferase) inhibitor;
ion transport inhibitor;
loop diuretic
iodoacetamide
[no description available]		2.4110
ethylmaleimide
Ethylmaleimide: A sulfhydryl reagent that is widely used in experimental biochemical studies.		2.4110maleimidesanticoronaviral agent;
EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor;
EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor;
EC 2.7.1.1 (hexokinase) inhibitor
methionine
Methionine: A sulfur-containing essential L-amino acid that is important in many body functions.. methionine : A sulfur-containing amino acid that is butyric acid bearing an amino substituent at position 2 and a methylthio substituent at position 4.		2.0210aspartate family amino acid;
L-alpha-amino acid;
methionine zwitterion;
methionine;
proteinogenic amino acid		antidote to paracetamol poisoning;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical
methyl iodide
methyl iodide: RN given refers to unlabeled cpd with MF of CH3-I. iodomethane : A member of the class of iodomethanes that is methane in which one of the hydrogens is replaced by iodine.		2.4110iodomethanes;
methyl halides		fumigant insecticide
diphenyl
diphenyl: RN given refers to unlabeled cpd; structure		1.9310aromatic fungicide;
benzenes;
biphenyls		antifungal agrochemical;
antimicrobial food preservative
n-octanethiol
octane-1-thiol : An alkanethiol that is octane substituted by a thiol group at position 1.		2.0510alkanethiol
oxazoles
Oxazoles: Five-membered heterocyclic ring structures containing an oxygen in the 1-position and a nitrogen in the 3-position, in distinction from ISOXAZOLES where they are at the 1,2 positions.. 1,3-oxazole : A five-membered monocyclic heteroarene that is an analogue of cyclopentadiene with O in place of CH2 at position 1 and N in place of CH at position 3.. oxazole : An azole based on a five-membered heterocyclic aromatic skeleton containing one N and one O atom.		1.93101,3-oxazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene
hydrazine
diamine : Any polyamine that contains two amino groups.		2.1110azane;
hydrazines		EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor
methyl triflate
[no description available]		2.1110
deuterium
Deuterium: The stable isotope of hydrogen. It has one neutron and one proton in the nucleus.		2.0810dihydrogen
alkenes
[no description available]		2.4110
glutathione disulfide
Glutathione Disulfide: A GLUTATHIONE dimer formed by a disulfide bond between the cysteine sulfhydryl side chains during the course of being oxidized.		2.4110glutathione derivative;
organic disulfide		Escherichia coli metabolite;
mouse metabolite
cobalt
Cobalt: A trace element that is a component of vitamin B12. It has the atomic symbol Co, atomic number 27, and atomic weight 58.93. It is used in nuclear weapons, alloys, and pigments. Deficiency in animals leads to anemia; its excess in humans can lead to erythrocytosis.. cobalt(1+) : A monovalent inorganic cation obtained from cobalt.. cobalt atom : A cobalt group element atom that has atomic number 27.		2.0510cobalt group element atom;
metal allergen		micronutrient
oxazolidine
oxazolidine: structure given in first source		1.9310oxazolidine
vitamin b 12
Vitamin B 12: A cobalt-containing coordination compound produced by intestinal micro-organisms and found also in soil and water. Higher plants do not concentrate vitamin B 12 from the soil and so are a poor source of the substance as compared with animal tissues. INTRINSIC FACTOR is important for the assimilation of vitamin B 12.		2.0510
ConditionIndicatedRelationship StrengthStudiesTrials