Compounds > methyl 3,5-diiodo-4-(4'-methoxyphenoxy)benzoate
Page last updated: 2024-11-12

methyl 3,5-diiodo-4-(4'-methoxyphenoxy)benzoate

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

methyl 3,5-diiodo-4-(4'-methoxyphenoxy)benzoate: a tubulin-binding agent; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID9936119
SCHEMBL ID237992
MeSH IDM0403943

Synonyms (7)

Synonym
methyl 3,5-diiodo-4-(4-methoxyphenoxy)benzoate
SCHEMBL237992
methyl 3,5-diiodo-4-(4'-methoxyphenoxy)benzoate
BDXPYXUQAYIUFG-UHFFFAOYSA-N
methyl-3,5-diiodo-4-(4'-methoxyphenoxy)benzoate
33927-09-2
3,5-diiodo-4(4'-methoxyphenoxy)benzoic acid methyl ester

Research Excerpts

Bioavailability

ExcerptReferenceRelevance
" This novel antitumor agent is orally bioavailable and well tolerated by animals."( Oncocidin A1: a novel tubulin-binding drug with antitumor activity against human breast and ovarian carcinoma xenografts in nude mice.
Chen, X; Knapp, AM; Laderoute, KR; Pine, P; Tusé, D, 1998)		0.3
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's3 (42.86)18.2507
2000's3 (42.86)29.6817
2010's0 (0.00)24.3611
2020's1 (14.29)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.17

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.17 (24.57)
Research Supply Index2.08 (2.92)
Research Growth Index4.25 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.17)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (14.29%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (85.71%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
5-iodo-6-amino-1,2-benzopyrone
[no description available]		210
iniparib
[no description available]		210carbonyl compound;
organohalogen compound
warfarin
Warfarin: An anticoagulant that acts by inhibiting the synthesis of vitamin K-dependent coagulation factors. Warfarin is indicated for the prophylaxis and/or treatment of venous thrombosis and its extension, pulmonary embolism, and atrial fibrillation with embolization. It is also used as an adjunct in the prophylaxis of systemic embolism after myocardial infarction. Warfarin is also used as a rodenticide.. warfarin : A racemate comprising equal amounts of (R)- and (S)-warfarin. Extensively used as both an anticoagulant drug and as a pesticide against rats and mice.. 4-hydroxy-3-(3-oxo-1-phenylbutyl)-1-benzopyran-2-one : A member of the class of coumarins that is 4-hydroxycoumarin which is substituted at position 3 by a 1-phenyl-3-oxo-1-butyl group.		210benzenes;
hydroxycoumarin;
methyl ketone
ConditionIndicatedRelationship StrengthStudiesTrials
Granulocytic Leukemia
[description not available]		02.3110
Leukemia, Myeloid
Form of leukemia characterized by an uncontrolled proliferation of the myeloid lineage and their precursors (MYELOID PROGENITOR CELLS) in the bone marrow and other sites.		02.3110
Breast Cancer
[description not available]		02.420
Breast Neoplasms
Tumors or cancer of the human BREAST.		02.420
Cancer of Ovary
[description not available]		01.9910
Ovarian Neoplasms
Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.		01.9910
Angiogenesis, Pathologic
[description not available]		0210
Corneal Angiogenesis
[description not available]		0210
Experimental Mammary Neoplasms
[description not available]		0210
Corneal Neovascularization
New blood vessels originating from the corneal blood vessels and extending from the limbus into the adjacent CORNEAL STROMA. Neovascularization in the superficial and/or deep corneal stroma is a sequel to numerous inflammatory diseases of the ocular anterior segment, such as TRACHOMA, viral interstitial KERATITIS, microbial KERATOCONJUNCTIVITIS, and the immune response elicited by CORNEAL TRANSPLANTATION.		0210