Page last updated: 2024-12-10

mb 5

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

malbrancheamide B: from the culture medium and mycelia of the ascomycete Malbranchea aurantiaca; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID24858870
CHEMBL ID461147
MeSH IDM0047155

Synonyms (5)

Synonym
malbrancheamide b
CHEMBL461147
(5as,12as,13as)-9-chloro-12,12-dimethyl-2,3,11,12,12a,13-hexahydro-1h,5h,6h-5a,13a-(epiminomethano)indolizino[7,6-b]carbazol-14-one
mb5 ,
(1s,13s,15s)-7-chloro-12,12-dimethyl-10,19,21-triazahexacyclo[13.5.2.01,13.03,11.04,9.015,19]docosa-3(11),4(9),5,7-tetraen-22-one
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (2)

Assay IDTitleYearJournalArticle
AID411091Ratio of IC50 of chlorpromazine to IC50 of compound for bovine brain PDE12008Bioorganic & medicinal chemistry letters, Dec-15, Volume: 18, Issue:24
Calmodulin inhibitory activity of the malbrancheamides and various analogs.
AID411090Inhibition of bovine brain PDE12008Bioorganic & medicinal chemistry letters, Dec-15, Volume: 18, Issue:24
Calmodulin inhibitory activity of the malbrancheamides and various analogs.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]