| Substance | Relationship Strength | Studies | Trials | Classes | Roles |
|---|
gamma-aminobutyric acid
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.. gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4. | 2 | 1 | 0 | amino acid zwitterion;
gamma-amino acid;
monocarboxylic acid | human metabolite;
neurotransmitter;
Saccharomyces cerevisiae metabolite;
signalling molecule |
fenvalerate
fenvalerate: synthetic pyrethroid; RN given refers to cpd without isomeric designation; structure. fenvalerate : A carboxylic ester obtained by formal condensation between 2-(4-chlorophenyl)-3-methylbutyric acid and cyano(3-phenoxyphenyl)methanol. | 1.99 | 1 | 0 | aromatic ether;
carboxylic ester;
monochlorobenzenes | pyrethroid ester acaricide;
pyrethroid ester insecticide |
colchicine
(S)-colchicine : A colchicine that has (S)-configuration. It is a secondary metabolite, has anti-inflammatory properties and is used to treat gout, crystal-induced joint inflammation, familial Mediterranean fever, and many other conditions. | 2 | 1 | 0 | alkaloid;
colchicine | anti-inflammatory agent;
gout suppressant;
mutagen |
pyrrolidonecarboxylic acid
Pyrrolidonecarboxylic Acid: A cyclized derivative of L-GLUTAMIC ACID. Elevated blood levels may be associated with problems of GLUTAMINE or GLUTATHIONE metabolism.. 5-oxo-L-proline : An optically active form of 5-oxoproline having L-configuration. | 2.4 | 2 | 0 | 5-oxoproline;
L-proline derivative;
non-proteinogenic L-alpha-amino acid | algal metabolite |
substance p
[no description available] | 1.99 | 1 | 0 | peptide | neurokinin-1 receptor agonist;
neurotransmitter;
vasodilator agent |
mezlocillin
Kassinin: Dodecapeptide tachykinin found in the central nervous system of the amphibian Kassina senegalensis. It is similar in structure and action to other tachykinins, but is especially effective in contracting smooth muscle tissue and stimulating the micturition reflex. | 1.98 | 1 | 0 | | |
proctolin
proctolin: neurotransmitter in arthropods or invertebrates | 1.99 | 1 | 0 | | |
locustatachykinin ii protein, locusta migratoria
locustatachykinin II protein, Locusta migratoria: amino acid sequence given in first source; from extracts of brain complexes of the migratory locust, Locusta migratoria; exhibits sequence homologies with the vertebrate tachykinins | 3.09 | 5 | 0 | | |
locustatachykinin iii protein, locusta migratoria
locustatachykinin III protein, insect: amino acid sequence given in first source; isolated from locust Locusta migratoria | 2.69 | 3 | 0 | | |
locustatachykinin iv protein, locusta migratoria
locustatachykinin IV protein, insect: amino acid sequence given in first source; isolated from locust Locusta migratoria | 2.69 | 3 | 0 | | |
capsaicin
ALGRX-4975: an injectable capsaicin (TRPV1 receptor agonist) formulation for longlasting pain relief. capsaicinoid : A family of aromatic fatty amides produced as secondary metabolites by chilli peppers. | 2 | 1 | 0 | capsaicinoid | non-narcotic analgesic;
TRPV1 agonist;
voltage-gated sodium channel blocker |
allatostatin 1
allatostatin 1: inhibits juvenile hormone synthesis; from reproductively active females | 2.05 | 1 | 0 | | |
tetrodotoxin
Tetrodotoxin: An aminoperhydroquinazoline poison found mainly in the liver and ovaries of fishes in the order TETRAODONTIFORMES, which are eaten. The toxin causes paresthesia and paralysis through interference with neuromuscular conduction.. tetrodotoxin : A quinazoline alkaloid that is a marine toxin isolated from fish such as puffer fish. It has been shown to exhibit potential neutotoxicity due to its ability to block voltage-gated sodium channels. | 1.99 | 1 | 0 | azatetracycloalkane;
oxatetracycloalkane;
quinazoline alkaloid | animal metabolite;
bacterial metabolite;
marine metabolite;
neurotoxin;
voltage-gated sodium channel blocker |
fmrfamide
FMRFamide: A molluscan neuroactive peptide which induces a fast excitatory depolarizing response due to direct activation of amiloride-sensitive SODIUM CHANNELS. (From Nature 1995; 378(6558): 730-3) | 2 | 1 | 0 | | |
lucifer yellow
lucifer yellow: RN given refers to di-Li salt | 2 | 1 | 0 | organic lithium salt | fluorochrome |
leucokinin 1
leucokinin 1: isolated from the mosquito Aedes aegypti; amino acid sequence in first source; do not confuse with leucokinin I, from the bowfly | 2.05 | 1 | 0 | | |
pyrethrins
[no description available] | 1.99 | 1 | 0 | | |
allatotropin
allatotropin: from cerebral or corpora cardiaca of locusts & moths | 2 | 1 | 0 | | |