Compounds > lhrh, n-ac-naphthyl(1)-(4-cl-phe)(2)-trp(3)-arg(6)-ala(10)-
Page last updated: 2024-10-15

lhrh, n-ac-naphthyl(1)-(4-cl-phe)(2)-trp(3)-arg(6)-ala(10)-

Description

LHRH, N-Ac-naphthyl(1)-(4-Cl-Phe)(2)-Trp(3)-Arg(6)-Ala(10)-: RN given refers to the all (D)-isomer; gonadorelin antagonist [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID16131287
MeSH IDM0168126

Synonyms (8)

Synonym
1-n-ac-naphthyl-2-(4-cl-phe)-3-trp-6-arg-10-ala-lhrh
lhrh-nptaa
lhrh, n-acetylnaphthyl(1)-4-chlorophenylalanyl(2)-tryptophyl(3)-arginyl(6)-alanine(10)-
lhrh, n-ac-naphthyl(1)-(4-cl-phe)(2)-trp(3)-arg(6)-ala(10)-
d-alaninamide, n-acetyl-3-(1-naphthalenyl)-d-alanyl-4-chloro-d-phenylalanyl-d-tryptophyl-l-seryl-l-tyrosyl-d-arginyl-l-leucyl-l-arginyl-l-prolyl-
gnrh, n-ac-naphthyl(1)-(4-cl-phe)(2)-trp(3)-arg(6)-ala(10)-
86044-78-2
DTXSID30235363
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (28.57)18.7374
1990's5 (71.43)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
androstenedione
Androstenedione: A delta-4 C19 steroid that is produced not only in the TESTIS, but also in the OVARY and the ADRENAL CORTEX. Depending on the tissue type, androstenedione can serve as a precursor to TESTOSTERONE as well as ESTRONE and ESTRADIOL.. androst-4-ene-3,17-dione : A 3-oxo Delta(4)-steroid that is androst-4-ene substituted by oxo groups at positions 3 and 17. It is a steroid hormone synthesized in the adrenal glands and gonads.		1.971017-oxo steroid;
3-oxo-Delta(4) steroid;
androstanoid		androgen;
Daphnia magna metabolite;
human metabolite;
mouse metabolite
cloprostenol
Cloprostenol: A synthetic prostaglandin F2alpha analog. The compound has luteolytic effects and is used for the synchronization of estrus in cattle.		1.9710prostanoid
ConditionIndicatedRelationship StrengthStudiesTrials
Hypergonadotropic Hypogonadism
[description not available]		01.9710
Hypogonadism
Condition resulting from deficient gonadal functions, such as GAMETOGENESIS and the production of GONADAL STEROID HORMONES. It is characterized by delay in GROWTH, germ cell maturation, and development of secondary sex characteristics. Hypogonadism can be due to a deficiency of GONADOTROPINS (hypogonadotropic hypogonadism) or due to primary gonadal failure (hypergonadotropic hypogonadism).		01.9710
Pregnancy
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.		01.9710
Sterility, Male
[description not available]		01.9710
Infertility, Male
The inability of the male to effect FERTILIZATION of an OVUM after a specified period of unprotected intercourse. Male sterility is permanent infertility.		01.9710