Page last updated: 2024-11-13

leiodermatolide

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

leiodermatolide: an antimitotic agent isolated from the marine sponge Leiodermatium; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID71528796
CHEMBL ID4083537
MeSH IDM0558903

Synonyms (5)

Synonym
leiodermatolide
Q44316165
CHEMBL4083537
1006046-07-6
DTXSID201043920

Research Excerpts

Overview

Leiodermatolide is an antimitotic macrolide isolated from the marine sponge.

ExcerptReferenceRelevance
"Leiodermatolide is an antimitotic macrolide isolated from the marine sponge Leiodermatium sp. "( Total synthesis of the antimitotic marine macrolide (-)-leiodermatolide.
Dalby, SM; Millican, DC; Ng, KK; Paterson, I; Williams, S, 2014
)
2.09
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (1)

Assay IDTitleYearJournalArticle
AID1478487Cytotoxicity against human Aspc-1 cells incubated for 72 hrs by MTT assay2017Journal of natural products, 03-24, Volume: 80, Issue:3
Analogues of the Potent Antitumor Compound Leiodermatolide from a Deep-Water Sponge of the Genus Leiodermatium.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (9)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's9 (100.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other9 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]