Compounds > ledoxantrone
Page last updated: 2024-12-08

ledoxantrone

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

ledoxantrone: benzothiopyrano-indazole cpd; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID366673
CHEMBL ID38458
SCHEMBL ID5075871
MeSH IDM0577847

Synonyms (20)

Synonym
8hbt2jrj5t ,
113457-05-9
unii-8hbt2jrj5t
2h-(1)benzothiopyrano(4,3,2-cd)indazol-8-ol, 5-((2-aminoethyl)amino)-2-(2-(diethylamino)ethyl)-
ledoxantrone [inn]
NCI60_011759
sedoxantrone
CHEMBL38458
ledoxantrone
ledoxantrone [who-dd]
5-((2-aminoethyl)amino)-2-(2-(diethylamino)ethyl)-2h-(1)benzothiopyrano(4,3,2-cd)indazol-8-ol
HPCHDLLMIWHKBW-UHFFFAOYSA-N
5-[(2-aminoethyl)amino]-2-[2-(diethylamino)ethyl]-2h-[1]-benzothiopyrano[4,3,2-cd]indazol-8-ol
SCHEMBL5075871
10-(2-aminoethylamino)-14-[2-(diethylamino)ethyl]-8-thia-14,15-diazatetracyclo[7.6.1.02,7.013,16]hexadeca-1,3,6,9,11,13(16)-hexaen-5-one
2h-[1]benzothiopyrano[4,3,2-cd]indazol-8-ol, 5-[(2-aminoethyl)amino]-2-[2-(diethylamino)ethyl]-
DTXSID40921068
5-[(2-aminoethyl)amino]-2-[2-(diethylamino)ethyl]-1,2-dihydro-8h-[1]benzothiopyrano[4,3,2-cd]indazol-8-one
5-((2-aminoethyl)amino)-2-(2-(diethylamino)ethyl)-2h-thiochromeno[4,3,2-cd]indazol-8-ol
Q27270506
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (10)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (10.00)18.7374
1990's3 (30.00)18.2507
2000's6 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.05

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.05 (24.57)
Research Supply Index2.94 (2.92)
Research Growth Index4.99 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.05)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials8 (80.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other2 (20.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
indazoles
Indazoles: A group of heterocyclic aromatic organic compounds consisting of the fusion of BENZENE and PYRAZOLES.		6.92108indazole
ConditionIndicatedRelationship StrengthStudiesTrials
Adenocarcinoma, Basal Cell
[description not available]		0533
Cancer of Prostate
[description not available]		04.6432
Hormone-Dependent Neoplasms
[description not available]		03.411
Adenocarcinoma
A malignant epithelial tumor with a glandular organization.		0533
Prostatic Neoplasms
Tumors or cancer of the PROSTATE.		04.6432
Leukocytopenia
[description not available]		03.3811
Colorectal Cancer
[description not available]		04.3522
Leukopenia
A decrease in the number of LEUKOCYTES in a blood sample below the normal range (LEUKOCYTE COUNT less than 4000).		03.3811
Colorectal Neoplasms
Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.		04.3522
Benign Neoplasms
[description not available]		04.3522
Neoplasms
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.		04.3522
Cancer of Ovary
[description not available]		04.3522
Local Neoplasm Recurrence
[description not available]		04.3522
Ovarian Neoplasms
Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.		04.3522
Blood Pressure, Low
[description not available]		03.3911
Hypotension
Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.		03.3911
Neutropenia
A decrease in the number of NEUTROPHILS found in the blood.		03.3911
Leukemia L 1210
[description not available]		01.9710