KYN 54: structure given in first source; a novel synthesized retinoid; potential chemopreventive agent for intestinal neoplasm [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 6439189 |
| SCHEMBL ID | 7518444 |
| MeSH ID | M0207502 |
| Synonym |
|---|
| 91269-98-6 |
| ea2a4gnx48 , |
| unii-ea2a4gnx48 |
| ccris 7131 |
| kyn 54 |
| 2(5h)-furanone, 5-hydroxy-4-(2-phenylethenyl)-, (e)- |
| (e)-5-hydroxy-4-(2-phenylethenyl)-2(5h)-furanone |
| SCHEMBL7518444 |
| kyk-54 |
| 2(5h)-furanone, 5-hydroxy-4-((1e)-2-phenylethenyl)- |
| kyn-54 |
| kyk 54 |
| 5-hydroxy-4-(2-phenyl-(e)-ethenyl)-2(5h)furanone |
| Q27277062 |
| Excerpt | Relevance | Reference |
|---|---|---|
| " These rats were fed diet containing 100 or 200 ppm KYN-54 for 5 weeks, starting 1 week before the first dosing of AOM." | ( Suppression of azoxymethane-induced colonic aberrant crypt foci by dietary exposure to a novel synthesized retinoidal butenolide, 5-hydroxy-4-(2-phenyl-(E)ethenyl)-2(5H)-furanone, in rats. Hara, A; Hirose, Y; Kawamori, T; Mori, H; Satoh, K; Tamai, Y; Tanaka, T; Torihara, M; Yamahara, J, 1995) | 0.29 |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.37) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 7 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||