kealiinine a

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

kealiinine A: from the marine sponge Leucetta chagosensis; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	9997944
CHEMBL ID	488196
MeSH ID	M0582043

Synonyms (3)

Synonym
CHEMBL488196
kealiinine a
2-amino-6-methoxy-9-(4-methoxyphenyl)-3-methylbenzo[f]benzimidazol-7-ol

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (4)

Assay ID	Title	Year	Journal	Article
AID401945	Antifungal activity against Cladosporium herbarum DSM 63422 at 20 ug/disk after 24 hrs by agar plate diffusion assay	2004	Journal of natural products, May, Volume: 67, Issue:5	New imidazole alkaloids from the Indonesian sponge Leucetta chagosensis.
AID780097	Cytotoxicity against human MCF7 cells after 96 hrs by MTT assay	2013	Bioorganic & medicinal chemistry letters, Nov-15, Volume: 23, Issue:22	Total syntheses and cytotoxicity of kealiiquinone, 2-deoxy-2-aminokealiiquinone and analogs.
AID401944	Toxicity in Artemia salina at 20 ug/mL	2004	Journal of natural products, May, Volume: 67, Issue:5	New imidazole alkaloids from the Indonesian sponge Leucetta chagosensis.
AID1435057	Cytotoxicity against human MCF7 cells assessed as growth inhibition after 96 hrs by MTT assay	2017	Bioorganic & medicinal chemistry, 03-01, Volume: 25, Issue:5	Total synthesis and cytotoxicity of Leucetta alkaloids.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (20.00)	29.6817
2010's	4 (80.00)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	5 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Trials	Classes	Roles
kealiinine b kealiinine B: from the marine sponge Leucetta chagosensis; structure in first source	3.03	4	0
kealiinine c kealiinine C: from the marine sponge Leucetta chagosensis; structure in first source	3.03	4	0

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