Compounds > jorunnamycin a
Page last updated: 2024-11-12

jorunnamycin a

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

jorunnamycin A: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID16043476
CHEMBL ID549905
CHEBI ID188643
MeSH IDM0589633

Synonyms (8)

Synonym
journnamycin a
CHEMBL549905
(1r,2s,10r,12r,13s)-10-(hydroxymethyl)-7,18-dimethoxy-6,17,21-trimethyl-5,8,16,19-tetraoxo-11,21-diazapentacyclo[11.7.1.02,11.04,9.015,20]henicosa-4(9),6,15(20),17-tetraene-12-carbonitrile
jorunnamycin a
CHEBI:188643
701911-92-4
(6s,7r,9r,14as,15r)-1,5,6,7,9,10,13,14,14a,15-decahydro-9-(hydroxymethyl)-2,11-dimethoxy-3,12,16-trimethyl-1,4,10,13-tetraoxo-6,15-imino-4h-isoquino[3,2-b][3]benzazocine-7-carbonitrile
DTXSID001098705
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
isoquinolinesA class of organic heteropolycyclic compound consisting of isoquinoline and its substitution derivatives.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (62)

Assay IDTitleYearJournalArticle
AID1538830Induction of anoikis in human H460 cells under detachment conditions assessed as decrease in MCL-1 level at 0.05 to 0.5 uM after 12 hrs by Western blot analysis2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538839Induction of anoikis in human H460 cells harboring with p53 mutant under detachment conditions assessed as effect on P53 level at 0.05 to 0.5 uM after 12 hrs by Western blot analysis2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538836Inhibition of AKT phosphorylation in human H460 cells under detachment conditions at 0.05 to 0.5 uM after 12 hrs by Western blot analysis2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538864Induction of anoikis in human H23 cells harboring with p53 mutant under detachment conditions assessed as effect on P53 level at 0.05 to 0.5 uM after 12 hrs by Western blot analysis2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538832Induction of anoikis in human H460 cells under detachment conditions assessed as increase in Bax level at 0.05 to 0.5 uM after 12 hrs by Western blot analysis2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538819Antiproliferative activity against human H460 cells under detachment conditions assessed as reduction in cell viability at 0.1 to 0.5 uM after 3 hrs by XTT assay2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538869Inhibition of epithelial-mesenchymal transition in human H23 cells harboring with p53 mutant under detachment conditions assessed as decrease in snail protein level 0.05 to 0.5 uM after 12 hrs by Western blot analysis2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538816Induction of apoptosis in human H460 cells at 1 uM after 24 hrs by Hoechst 33342/propidium iodide staining based fluorescent microscopic method2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538822Induction of anoikis in human H460 cells under detachment conditions at 0.05 to 0.5 uM after 24 hrs by Hoechst 33342/propidium iodide staining based fluorescent microscopic method2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538838Down regulation of caveolin-1 human H460 cells under detachment conditions at 0.05 to 0.5 uM after 12 hrs by Western blot analysis2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538831Induction of anoikis in human H460 cells under detachment conditions assessed as decrease in BCL-2 level at 0.1 to 0.5 uM after 12 hrs by Western blot analysis2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538825Induction of apoptosis in human H460 cells under detachment conditions assessed as late apoptotic cells at 0.5 uM after 24 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 15.44%)2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID427235Cytotoxicity against human HCT116 cells after 3 days by MTT assay2009Bioorganic & medicinal chemistry, Jul-01, Volume: 17, Issue:13
Chemistry of renieramycins. Part 8: synthesis and cytotoxicity evaluation of renieramycin M-jorunnamycin A analogues.
AID1538868Inhibition of epithelial-mesenchymal transition in human H23 cells harboring with p53 mutant under detachment conditions assessed as increase in E-cadherin protein level 0.05 to 0.5 uM after 12 hrs by Western blot analysis2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538870Inhibition of epithelial-mesenchymal transition in human H23 cells harboring with p53 mutant under detachment conditions assessed as decrease in vimentin protein level 0.05 to 0.5 uM after 12 hrs by Western blot analysis2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538850Induction of apoptosis in human NCI-H292 cells under detachment conditions assessed as early apoptotic cells at 0.5 uM after 24 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 29.96%)2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538861Induction of anoikis in human H23 cells harboring with p53 mutant under detachment conditions assessed as decrease in MCL-1 level at 0.05 to 0.5 uM after 12 hrs by Western blot analysis2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538867Inhibition of ERK phosphorylation in human H23 cells harboring with p53 mutant under detachment conditions at 0.05 to 0.5 uM after 12 hrs by Western blot analysis2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538837Inhibition of ERK phosphorylation in human H460 cells under detachment conditions at 0.05 to 0.5 uM after 12 hrs by Western blot analysis2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538865Down regulation of caveolin-1 human H23 cells harboring with p53 mutant under detachment conditions at 0.05 to 0.5 uM after 12 hrs by Western blot analysis2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538821Induction of apoptosis in human H460 cells under detachment conditions assessed as accumulation of necrotic cells at 0.05 to 0.5 uM after 24 hrs by Hoechst 33342/propidium iodide staining based fluorescent microscopic method2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538835Effect on total ERK protein level in human H460 cells under detachment conditions at 0.05 to 0.5 uM after 12 hrs by Western blot analysis2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538840Inhibition of epithelial-mesenchymal transition in human H460 cells under detachment conditions assessed as increase in E-cadherin protein level 0.05 to 0.5 uM after 12 hrs by Western blot analysis2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538855Induction of apoptosis in human H23 cells under detachment conditions assessed as late apoptotic cells at 0.5 uM after 24 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 2.82%)2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538851Induction of apoptosis in human NCI-H292 cells under detachment conditions assessed as late apoptotic cells at 0.5 uM after 24 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 28.21%)2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538858Inhibition of colony formation in human NCI-H292 cells under detachment conditions assessed as reduction in size of colonies at 0.1 to 0.5 uM after 14 days by microscopic method2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538828Inhibition of colony formation in human H460 cells under detachment conditions assessed as reduction in number of colonies at 0.1 to 0.5 uM after 14 days by microscopic method2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538860Inhibition of colony formation in human H23 cells under detachment conditions assessed as reduction in size of colonies at 0.1 to 0.5 uM after 14 days by microscopic method2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538853Induction of apoptosis in human H23 cells under detachment conditions assessed as viable cells at 0.5 uM after 24 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 69.96%)2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538863Induction of anoikis in human H23 cells harboring with p53 mutant under detachment conditions assessed as effect on Bax level at 0.05 to 0.5 uM after 12 hrs by Western blot analysis2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538856Induction of apoptosis in human H23 cells under detachment conditions assessed as necrotic cells at 0.5 uM after 24 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 0.41%)2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538866Inhibition of AKT phosphorylation in human H23 cells harboring with p53 mutant under detachment conditions at 0.05 to 0.5 uM after 12 hrs by Western blot analysis2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID427237Cytotoxicity against human QG56 cells at 1.4 to 100 nM after 3 days by MTT assay2009Bioorganic & medicinal chemistry, Jul-01, Volume: 17, Issue:13
Chemistry of renieramycins. Part 8: synthesis and cytotoxicity evaluation of renieramycin M-jorunnamycin A analogues.
AID1538871Inhibition of epithelial-mesenchymal transition in human H23 cells harboring with p53 mutant under detachment conditions assessed as increase in claudin-1 protein level 0.05 to 0.5 uM after 12 hrs by Western blot analysis2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538847Antiproliferative activity against human H23 cells under detachment conditions assessed as reduction in cell viability at 0.05 to 0.5 uM up to 24 hrs by XTT assay2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538827Induction of anoikis in human H460 cells under detachment conditions assessed as fold change at 0.5 uM after 24 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometric analysis2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538834Effect on total AKT protein level in human H460 cells under detachment conditions at 0.05 to 0.5 uM after 12 hrs by Western blot analysis2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538813Induction of apoptosis in human H460 cells assessed as accumulation of necrotic cells at 0.05 to 1 uM after 24 hrs by Hoechst 33342/propidium iodide staining based fluorescent microscopic method2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538846Antiproliferative activity against human NCI-H292 cells under detachment conditions assessed as reduction in cell viability at 0.05 to 0.5 uM up to 24 hrs by XTT assay2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538817Induction of apoptosis in human H460 cells at 0.05 to 0.5 uM after 24 hrs by Hoechst 33342/propidium iodide staining based fluorescent microscopic method2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538824Induction of apoptosis in human H460 cells under detachment conditions assessed as early apoptotic cells at 0.5 uM after 24 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 22.55%)2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538862Induction of anoikis in human H23 cells harboring with p53 mutant under detachment conditions assessed as decrease in BCL-2 level at 0.05 to 0.5 uM after 12 hrs by Western blot analysis2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538841Inhibition of epithelial-mesenchymal transition in human H460 cells under detachment conditions assessed as decrease in snail protein level 0.05 to 0.5 uM after 12 hrs by Western blot analysis2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538859Inhibition of colony formation in human H23 cells under detachment conditions assessed as reduction in number of colonies at 0.1 to 0.5 uM after 14 days by microscopic method2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538843Inhibition of epithelial-mesenchymal transition in human H460 cells under detachment conditions assessed as increase in claudin-1 protein level 0.05 to 0.5 uM after 12 hrs by Western blot analysis2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538829Inhibition of colony formation in human H460 cells under detachment conditions assessed as reduction in size of colonies at 0.1 to 0.5 uM after 14 days by microscopic method2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538842Inhibition of epithelial-mesenchymal transition in human H460 cells under detachment conditions assessed as decrease in vimentin protein level 0.05 to 0.5 uM after 12 hrs by Western blot analysis2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538826Induction of apoptosis in human H460 cells under detachment conditions assessed as necrotic cells at 0.5 uM after 24 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 1.58%)2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538857Inhibition of colony formation in human NCI-H292 cells under detachment conditions assessed as reduction in number of colonies at 0.1 to 0.5 uM after 14 days by microscopic method2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538815Antiproliferative activity against human H460 cells assessed as reduction in cell viability at 0.05 to 0.5 uM after 24 hrs by MTT assay2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538844Antiproliferative activity against human NCI-H292 cells assessed as reduction in cell viability at 0.05 to 0.5 uM2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID427236Cytotoxicity against human MDA-MB-435 cells after 3 days by MTT assay2009Bioorganic & medicinal chemistry, Jul-01, Volume: 17, Issue:13
Chemistry of renieramycins. Part 8: synthesis and cytotoxicity evaluation of renieramycin M-jorunnamycin A analogues.
AID1538833Induction of anoikis in human H460 cells under detachment conditions after 12 hrs by Western blot analysis2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538820Induction of apoptosis in human H460 cells under detachment conditions at 0.05 to 0.5 uM after 24 hrs by Hoechst 33342/propidium iodide staining based fluorescent microscopic method2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538823Induction of apoptosis in human H460 cells under detachment conditions assessed as viable cells at 0.5 uM after 24 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 60.43%)2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538818Antiproliferative activity against human H460 cells under detachment conditions assessed as reduction in cell viability at 0.05 uM after 6 hrs by XTT assay2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538848Induction of anoikis in human H23 cells under detachment conditions assessed as reduction in cell viability at 0.05 uM up to 24 hrs by XTT assay2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538814Antiproliferative activity against human H460 cells assessed as reduction in cell viability at 0.1 to 0.5 uM after at 72 hrs by crystal violet staining assay2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538852Induction of apoptosis in human NCI-H292 cells under detachment conditions assessed as necrotic cells at 0.5 uM after 24 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 1.28%)2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538849Induction of apoptosis in human NCI-H292 cells under detachment conditions assessed as viable cells at 0.5 uM after 24 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 40.55%)2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538845Antiproliferative activity against human H23 cells assessed as reduction in cell viability at 0.05 to 0.5 uM2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
AID1538854Induction of apoptosis in human H23 cells under detachment conditions assessed as early apoptotic cells at 0.5 uM after 24 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 26.81%)2019Journal of natural products, 07-26, Volume: 82, Issue:7
Jorunnamycin A from
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (11)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (9.09)29.6817
2010's5 (45.45)24.3611
2020's5 (45.45)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 13.01

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index13.01 (24.57)
Research Supply Index2.48 (2.92)
Research Growth Index5.49 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (13.01)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (9.09%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other10 (90.91%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
aspartic acid
Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.. aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent. L-aspartic acid : The L-enantiomer of aspartic acid.		3.3510aspartate family amino acid;
aspartic acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
mouse metabolite;
neurotransmitter
carbostyril
Quinolones: A group of derivatives of naphthyridine carboxylic acid, quinoline carboxylic acid, or NALIDIXIC ACID.. quinolin-2(1H)-one : A quinolone that is 1,2-dihydroquinoline substituted by an oxo group at position 2.		4.7880monohydroxyquinoline;
quinolone		bacterial xenobiotic metabolite
tyrosine
Tyrosine: A non-essential amino acid. In animals it is synthesized from PHENYLALANINE. It is also the precursor of EPINEPHRINE; THYROID HORMONES; and melanin.. tyrosine : An alpha-amino acid that is phenylalanine bearing a hydroxy substituent at position 4 on the phenyl ring.		2.0810amino acid zwitterion;
erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid;
proteinogenic amino acid;
tyrosine		EC 1.3.1.43 (arogenate dehydrogenase) inhibitor;
fundamental metabolite;
micronutrient;
nutraceutical
kainic acid
Kainic Acid: (2S-(2 alpha,3 beta,4 beta))-2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid. Ascaricide obtained from the red alga Digenea simplex. It is a potent excitatory amino acid agonist at some types of excitatory amino acid receptors and has been used to discriminate among receptor types. Like many excitatory amino acid agonists it can cause neurotoxicity and has been used experimentally for that purpose.		3.3510dicarboxylic acid;
L-proline derivative;
non-proteinogenic L-alpha-amino acid;
pyrrolidinecarboxylic acid		antinematodal drug;
excitatory amino acid agonist
podophyllotoxin
Podophyllum: A genus of poisonous American herbs, family BERBERIDACEAE. The roots yield PODOPHYLLOTOXIN and other pharmacologically important agents. The plant was formerly used as a cholagogue and cathartic. It is different from the European mandrake, MANDRAGORA.		3.3510furonaphthodioxole;
lignan;
organic heterotetracyclic compound		antimitotic;
antineoplastic agent;
keratolytic drug;
microtubule-destabilising agent;
plant metabolite;
tubulin modulator
1,2,3,4-tetrahydroquinoline
1,2,3,4-tetrahydroquinoline: structure in first source. 1,2,3,4-tetrahydroquinoline : A member of the class of quinolines that is the 1,2,3,4-tetrahydro derivative of quinoline.		3.3510quinolines
saframycin a
saframycin A: structure given in first source		8.7120
aspergillomarasmine a
[no description available]		3.3510
jorumycin
jorumycin: structure in first source		7.7830
renieramycin m
renieramycin M: from the Thai sponge Xestospongia sp.; structure in first source		2.830
ConditionIndicatedRelationship StrengthStudiesTrials
Breast Cancer
[description not available]		02.0510
Carcinoma, Anaplastic
[description not available]		02.5320
Cancer of Colon
[description not available]		02.0510
Breast Neoplasms
Tumors or cancer of the human BREAST.		02.0510
Carcinoma
A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for cancer.		02.5320
Colonic Neoplasms
Tumors or cancer of the COLON.		02.0510
Cancer of Lung
[description not available]		02.9830
Lung Neoplasms
Tumors or cancer of the LUNG.		02.9830
Carcinoma, Non-Small Cell Lung
[description not available]		02.6120
Carcinoma, Non-Small-Cell Lung
A heterogeneous aggregate of at least three distinct histological types of lung cancer, including SQUAMOUS CELL CARCINOMA; ADENOCARCINOMA; and LARGE CELL CARCINOMA. They are dealt with collectively because of their shared treatment strategy.		02.6120
Adverse Drug Event
[description not available]		02.610
Bladder Cancer
[description not available]		07.610
Urinary Bladder Neoplasms
Tumors or cancer of the URINARY BLADDER.		02.610
Drug-Related Side Effects and Adverse Reactions
Disorders that result from the intended use of PHARMACEUTICAL PREPARATIONS. Included in this heading are a broad variety of chemically-induced adverse conditions due to toxicity, DRUG INTERACTIONS, and metabolic effects of pharmaceuticals.		02.610