Compounds > jensenone

Page last updated: 2024-11-12

jensenone

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

jensenone: a marsupial antifeedant from Eucalyptus; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	11594161
CHEMBL ID	427087
MeSH ID	M0469558

Synonyms (4)

Synonym
2,4,6-trihydroxy-5-(3-methylbutanoyl)benzene-1,3-dicarbaldehyde
jensenone
CHEMBL427087
LGXKQDDWMRYQJK-UHFFFAOYSA-N

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (11)

Assay ID	Title	Year	Journal	Article
AID284265	Antifungal activity against Candida albicans	2007	Bioorganic & medicinal chemistry, Jan-01, Volume: 15, Issue:1	Antiprotozoal and antimicrobial activities of O-alkylated and formylated acylphloroglucinols.
AID284257	Antileishmanial activity against Leishmania donovani promastigotes after 48 hrs by Alamar blue assay	2007	Bioorganic & medicinal chemistry, Jan-01, Volume: 15, Issue:1	Antiprotozoal and antimicrobial activities of O-alkylated and formylated acylphloroglucinols.
AID284263	Antibacterial activity against methicillin-resistant Staphylococcus aureus	2007	Bioorganic & medicinal chemistry, Jan-01, Volume: 15, Issue:1	Antiprotozoal and antimicrobial activities of O-alkylated and formylated acylphloroglucinols.
AID284273	Antimicrobial activity against Mycobacterium intracellular	2007	Bioorganic & medicinal chemistry, Jan-01, Volume: 15, Issue:1	Antiprotozoal and antimicrobial activities of O-alkylated and formylated acylphloroglucinols.
AID284269	Antimalarial activity against Plasmodium falciparum D6	2007	Bioorganic & medicinal chemistry, Jan-01, Volume: 15, Issue:1	Antiprotozoal and antimicrobial activities of O-alkylated and formylated acylphloroglucinols.
AID284274	Antifungal activity against Aspergillus fumigatus	2007	Bioorganic & medicinal chemistry, Jan-01, Volume: 15, Issue:1	Antiprotozoal and antimicrobial activities of O-alkylated and formylated acylphloroglucinols.
AID284271	Cytotoxicity against Vero cells up to 4.76 ug/mL by neutral red assay	2007	Bioorganic & medicinal chemistry, Jan-01, Volume: 15, Issue:1	Antiprotozoal and antimicrobial activities of O-alkylated and formylated acylphloroglucinols.
AID702540	Inhibition of c-MET assessed as inhibition of HGF-induced phosphorylation at 5 uM by Western blotting analysis	2012	Journal of medicinal chemistry, Sep-27, Volume: 55, Issue:18	Potent HGF/c-Met axis inhibitors from Eucalyptus globulus: the coupling of phloroglucinol and sesquiterpenoid is essential for the activity.
AID284270	Antimalarial activity against Plasmodium falciparum W2	2007	Bioorganic & medicinal chemistry, Jan-01, Volume: 15, Issue:1	Antiprotozoal and antimicrobial activities of O-alkylated and formylated acylphloroglucinols.
AID284268	Antifungal activity against Cryptococcus neoformans at 20 ug/mL	2007	Bioorganic & medicinal chemistry, Jan-01, Volume: 15, Issue:1	Antiprotozoal and antimicrobial activities of O-alkylated and formylated acylphloroglucinols.
AID284272	Cytotoxicity against LLC-PK1 cells up to 4.76 ug/mL by neutral red assay	2007	Bioorganic & medicinal chemistry, Jan-01, Volume: 15, Issue:1	Antiprotozoal and antimicrobial activities of O-alkylated and formylated acylphloroglucinols.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (4)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	3 (75.00)	29.6817
2010's	1 (25.00)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.53

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	12.53 (24.57)
Research Supply Index	1.79 (2.92)
Research Growth Index	4.32 (4.65)
Search Engine Demand Index	0.00 (26.88)
Search Engine Supply Index	0.00 (0.95)

This Compound (12.53)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	5 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Trials	Classes	Roles
phloroglucinol Phloroglucinol: A trinitrobenzene derivative with antispasmodic properties that is used primarily as a laboratory reagent.. phloroglucinol : A benzenetriol with hydroxy groups at position 1, 3 and 5.	2.42	2	0	benzenetriol; phenolic donor	algal metabolite
chloroquine Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.. chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.	2.03	1	0	aminoquinoline; organochlorine compound; secondary amino compound; tertiary amino compound	anticoronaviral agent; antimalarial; antirheumatic drug; autophagy inhibitor; dermatologic drug
ciprofloxacin Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.. ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.	2.03	1	0	aminoquinoline; cyclopropanes; fluoroquinolone antibiotic; N-arylpiperazine; quinolinemonocarboxylic acid; quinolone antibiotic; quinolone; zwitterion	antibacterial drug; antiinfective agent; antimicrobial agent; DNA synthesis inhibitor; EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor; environmental contaminant; topoisomerase IV inhibitor; xenobiotic
pentamidine Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.. pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.	2.03	1	0	aromatic ether; carboxamidine; diether	anti-inflammatory agent; antifungal agent; calmodulin antagonist; chemokine receptor 5 antagonist; EC 2.3.1.48 (histone acetyltransferase) inhibitor; NMDA receptor antagonist; S100 calcium-binding protein B inhibitor; trypanocidal drug; xenobiotic
2,4-diacetylphloroglucinol 2,4-diacetylphloroglucinol: produced by Pseudomonas aurantiaca. 2,4-diacetylphloroglucinol : A benzenetriol that is phloroglucinol in which two of the ring hydrogens are replaced by acetyl groups.	2.03	1	0	aromatic ketone; benzenetriol; diketone; methyl ketone	antifungal agent; bacterial metabolite
benzofurans Benzofurans: Compounds that contain a BENZENE ring fused to a furan ring.	2.02	1	0
macrocarpal a macrocarpal A: structure in first source	2.07	1	0
macrocarpal b macrocarpal B: structure in first source	2.07	1	0	sesquiterpenoid
amphotericin b Amphotericin B: Macrolide antifungal antibiotic produced by Streptomyces nodosus obtained from soil of the Orinoco river region of Venezuela.. amphotericin B : A macrolide antibiotic used to treat potentially life-threatening fungal infections.	2.03	1	0	antibiotic antifungal drug; macrolide antibiotic; polyene antibiotic	antiamoebic agent; antiprotozoal drug; bacterial metabolite
sideroxylonal c sideroxylonal C: formylated phloroglucinol from flowers of Eucalyptus albens; structure in first source	2.02	1	0