Compounds > isomurisolenin

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isomurisolenin

Description

isomurisolenin: an acetogenin from seeds of Annona reticulata; [MeSH]

Cross-References

ID Source	ID
PubMed CID	102121363
MeSH ID	M0289966

Synonyms (1)

Synonym
isomurisolenin

Research

Studies (37)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	17 (45.95)	18.2507
2000's	20 (54.05)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	3 (8.11%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	34 (91.89%)	84.16%

Substance	Studies	Classes	Roles	First Year	Last Year	Average Age	Relationship Strength	Trials	pre-1990	1990's	2000's	2010's	post-2020
khellin	1	furanochromone; organic heterotricyclic compound; oxacycle	anti-asthmatic agent; bronchodilator agent; cardiovascular drug; vasodilator agent	2001	2001	23.0	low	0	0	0	1	0	0
quinone	1	1,4-benzoquinones	cofactor; human xenobiotic metabolite; mouse metabolite	2001	2001	23.0	low	0	0	0	1	0	0
rotenone	1	organic heteropentacyclic compound; rotenones	antineoplastic agent; metabolite; mitochondrial NADH:ubiquinone reductase inhibitor; phytogenic insecticide; piscicide; toxin	1999	1999	25.0	low	0	0	1	0	0	0
4-butyrolactone	6	butan-4-olide	metabolite; neurotoxin	1998	2001	24.7	high	0	0	5	1	0	0
tetrahydrofuran	2	cyclic ether; oxolanes; saturated organic heteromonocyclic parent; volatile organic compound	polar aprotic solvent	2000	2004	22.0	low	0	0	1	1	0	0
butenolide	1	butenolide		2000	2000	24.0	low	0	0	1	0	0	0
4-hydroxy-25-desoxyneorollinicin	4			1999	2001	24.2	medium	0	0	3	1	0	0
hydroxyl radical	2	oxygen hydride; oxygen radical; reactive oxygen species		2000	2004	22.0	low	0	0	1	1	0	0
annonacin	1			2000	2000	24.0	low	0	0	1	0	0	0
acetogenins	1			2004	2004	20.0	low	0	0	0	1	0	0
squamocin	1	polyketide		1999	1999	25.0	low	0	0	1	0	0	0
chalcone	1	chalcone	EC 3.2.1.1 (alpha-amylase) inhibitor	1999	1999	25.0	low	0	0	1	0	0	0
mucocin	2	polyketide		2000	2001	23.5	high	0	0	1	1	0	0
licochalcone a	1	chalcones		1999	1999	25.0	low	0	0	1	0	0	0
10-hydroxyasimicin	1			1999	1999	25.0	high	0	0	1	0	0	0
nad	1	organophosphate oxoanion	cofactor; human metabolite; hydrogen acceptor; Saccharomyces cerevisiae metabolite	1999	1999	25.0	low	0	0	1	0	0	0
ubiquinone	1			1999	1999	25.0	low	0	0	1	0	0	0
laherradurin	1			2001	2001	23.0	high	0	0	0	1	0	0
warfarin	1	benzenes; hydroxycoumarin; methyl ketone		1999	1999	25.0	low	0	0	1	0	0	0

Condition	Indicated	Studies	First Year	Last Year	Average Age	Relationship Strength	Trials	pre-1990	1990's	2000's	2010's	post-2020
Adenocarcinoma	0	1	1998	1998	26.0	low	0	0	1	0	0	0
Adenocarcinoma, Basal Cell	0	1	1998	1998	26.0	low	0	0	1	0	0	0
Cancer of Colon	0	1	1998	1998	26.0	low	0	0	1	0	0	0
Cancer of Pancreas	0	1	1998	1998	26.0	low	0	0	1	0	0	0
Cancer of Prostate	0	1	1998	1998	26.0	low	0	0	1	0	0	0
Carcinoma, Hepatocellular	0	1	1998	1998	26.0	low	0	0	1	0	0	0
Colonic Neoplasms	0	1	1998	1998	26.0	low	0	0	1	0	0	0
Hepatocellular Carcinoma	0	1	1998	1998	26.0	low	0	0	1	0	0	0
Leishmania Infection	0	1	1999	1999	25.0	low	0	0	1	0	0	0
Leishmaniasis	0	1	1999	1999	25.0	low	0	0	1	0	0	0
Leukemia L 1210	0	1	2000	2000	24.0	low	0	0	1	0	0	0
Pancreatic Neoplasms	0	1	1998	1998	26.0	low	0	0	1	0	0	0
Prostatic Neoplasms	0	1	1998	1998	26.0	low	0	0	1	0	0	0

Safety/Toxicity (1)

Article	Year
Semisynthesis and cytotoxicity of amino acetogenins and derivatives. Bioorganic & medicinal chemistry, , Volume: 7, Issue:9	1999