Compounds > isomitraphylline
Page last updated: 2024-11-12

isomitraphylline

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

isomitraphylline: isolated from Uncaria tomentosa [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

FloraRankFlora DefinitionFamilyFamily Definition
Uncaria tomentosaspecies[no description available]RubiaceaeThe Madder plant family of the order Gentianales (formerly Rubiales), subclass Asteridae, class Magnoliopsida includes important medicinal plants that provide QUININE; IPECAC; and COFFEE. They have opposite leaves and interpetiolar stipules.[MeSH]

Cross-References

ID SourceID
PubMed CID11726520
SCHEMBL ID23259271
MeSH IDM0496837

Synonyms (20)

Synonym
4963-01-3
isomitraphylline
7-isomitraphylline
isomitraphyllin
isomitraphylline (constituent of cat's claw) [dsc]
unii-xkc69mv51v
ajmalicine oxindole a
xkc69mv51v ,
formosanan-16-carboxylic acid, 19-methyl-2-oxo-, methyl ester, (7alpha,19alpha)-
formosanan-16-carboxylic acid, 19-methyl-2-oxo-, methyl ester, (7.alpha.,19.alpha.)-
(1's,3s,4a's,5a's,10a'r)-methyl 1'-methyl-2-oxo-1',4a',5',5a',7',8',10',10a'-octahydrospiro[indoline-3,6'-pyrano[3,4-f]indolizine]-4'-carboxylate
Q27293881
SCHEMBL23259271
HY-120720
E88914
methyl (1s,4as,5as,6s,10ar)-1-methyl-2'-oxospiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-1h-indole]-4-carboxylate
CS-0078903
isomitraphylline (constituent of cat's claw)
AKOS040761901
FS-6908
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's4 (66.67)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 20.29

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index20.29 (24.57)
Research Supply Index2.08 (2.92)
Research Growth Index4.73 (4.65)
Search Engine Demand Index15.26 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (20.29)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
mitraphylline
mitraphylline: isolated from Uncaria tomentosa		3.1850indolizines
rhyncophylline
rhyncophylline: an oxindole; RN given refers to (7beta,16E,20alpha)-isomer		2.1510
uncarine e
uncarine E: stereoisomeric pentacyclic oxindoloindolizidine alkaloid from Uncaria tomentosa; structure in first source		2.4720indolizines
uncarine c
uncarine C: stereoisomeric pentacyclic oxindole alkaloid from Uncaria tomentosa; structure in first source		2.4720indolizines
ConditionIndicatedRelationship StrengthStudiesTrials
Acute Lymphoid Leukemia
[description not available]		02.0310
Precursor Cell Lymphoblastic Leukemia-Lymphoma
A neoplasm characterized by abnormalities of the lymphoid cell precursors leading to excessive lymphoblasts in the marrow and other organs. It is the most common cancer in children and accounts for the vast majority of all childhood leukemias.		02.0310