Page last updated: 2024-12-08

iodonium thiophene

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

iodonium thiophene: inhibitor of neutrophil superoxide generating oxidase; RN given for parent compound; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID162551
SCHEMBL ID218947
MeSH IDM0146544

Synonyms (7)

Synonym
iodonium thiophen
di-2-thienyliodonium
45955-43-9
iodonium thiophene
iodonium, di-2-thienyl-
SCHEMBL218947
DTXSID50196664

Research Excerpts

Bioavailability

ExcerptReferenceRelevance
" To improve the efficacy and bioavailability of the iodonium class NOX inhibitor diphenylene iodonium (DPI), we synthesized 36 analogs of DPI, focusing on improved solubility and functionalization."( Characterization of potent and selective iodonium-class inhibitors of NADPH oxidases.
Anderson, L; Antony, S; Doroshow, JH; Harris, E; Hill, K; Hossain, MT; Jiang, G; Juhasz, A; Kane, CT; Konaté, M; Liu, H; Lu, J; Meitzler, JL; Monks, A; Risbood, P; Roy, K; Wu, Y, 2017
)
0.46
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (9)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (11.11)18.7374
1990's4 (44.44)18.2507
2000's0 (0.00)29.6817
2010's4 (44.44)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.50

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.50 (24.57)
Research Supply Index2.30 (2.92)
Research Growth Index4.80 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.50)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other9 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]