humantenirine: isolated from root of Hu-Man-Teng (Gelsemium elegans Benth.); structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 11132403 |
| CHEMBL ID | 3597665 |
| MeSH ID | M0131983 |
| Synonym |
|---|
| humantenirine |
| 82375-30-2 |
| CHEMBL3597665 |
| CS-0131113 |
| HY-N7508 |
| (1r,2s,4s,7z,8r,9s)-7-ethylidene-1',6'-dimethoxyspiro[11-oxa-5-azatricyclo[6.3.1.04,9]dodecane-2,3'-indole]-2'-one |
| AKOS040760453 |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID1762379 | Analgesic activity in Kunming mouse assessed as inhibition of acetic acid-induced writhing at 5 mg/kg, ip pretreated with compound for 30 mins followed by acetic acid challenge and measured after 30 mins | |||
| AID1236142 | Cytotoxicity against human MCF7 cells assessed as inhibition of cell growth after 72 hrs by MTT assay | 2015 | Journal of natural products, Aug-28, Volume: 78, Issue:8 | Geleganidines A-C, Unusual Monoterpenoid Indole Alkaloids from Gelsemium elegans. |
| AID1236141 | Cytotoxicity against rat PC12 cells assessed as inhibition of cell growth after 72 hrs by MTT assay | 2015 | Journal of natural products, Aug-28, Volume: 78, Issue:8 | Geleganidines A-C, Unusual Monoterpenoid Indole Alkaloids from Gelsemium elegans. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||