| Substance | Relationship Strength | Studies | Trials | Classes | Roles |
|---|
soman
Soman: An organophosphorus compound that inhibits cholinesterase. It causes seizures and has been used as a chemical warfare agent. | 1.96 | 1 | 0 | phosphonic ester | |
sarin
Sarin: An organophosphorus ester compound that produces potent and irreversible inhibition of cholinesterase. It is toxic to the nervous system and is a chemical warfare agent.. isopropyl methylphosphonofluoridate : A phosphinic ester that is the isopropyl ester of methylphosphonofluoridic acid.. sarin : A racemate composed of equal amounts of (R)- and (S)-sarin. A potent and irreversible inhibitor of acetylcholinesterase that is toxic to the nervous system and is employed as a chemical warfare agent. | 2.38 | 2 | 0 | fluorine molecular entity;
phosphinic ester | |
obidoxime chloride
Obidoxime Chloride: Cholinesterase reactivator occurring in two interchangeable isomeric forms, syn and anti. | 2.88 | 4 | 0 | | |
enpiperate
enpiperate: RN given refers to parent cpd | 2.37 | 2 | 0 | | |
nadp
[no description available] | 1.96 | 1 | 0 | | |
piperidines
Piperidines: A family of hexahydropyridines. | 2.37 | 2 | 0 | | |
pralidoxime
pralidoxime: RN given refers to parent cpd; chloride was minor descriptor (75-80); on-line & Index Medicus search PRALIDOXIME COMPOUNDS (66-80). pralidoxime : A pyridinium ion that is 1-methylpyridinium substituted by a (hydroxyimino)methyl group at position 2. | 1.96 | 1 | 0 | pyridinium ion | antidote to organophosphate poisoning;
antidote to sarin poisoning;
cholinergic drug;
cholinesterase reactivator |
hlo 7
HLo 7: structure given in first source | 1.98 | 1 | 0 | organic molecular entity | |
asoxime chloride
[no description available] | 2.88 | 4 | 0 | | |
hgg 12
HGG 12: used therapeutically in organophosphate poisoning; structure; RN given refers to parent cpd | 2.88 | 4 | 0 | | |
trimedoxime bromide
Trimedoxime: Cholinesterase reactivator used as an antidote in alkyl phosphate poisoning. | 1.96 | 1 | 0 | | |