Page last updated: 2024-11-12

harzianolide

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

harzianolide: from the culture broth of Trichoderma sp. FKI-5513; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID15719532
CHEMBL ID2251566
SCHEMBL ID18270614
MeSH IDM0580821

Synonyms (6)

Synonym
CHEMBL2251566
harzianolide
SCHEMBL18270614
911809-23-9
3-[(2e,4e)-hexa-2,4-dienyl]-4-(2-hydroxypropyl)-2h-furan-5-one
rac-harzianolide
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (21)

Assay IDTitleYearJournalArticle
AID1090497Antimicrobial activity against Rhizoctonia solani assessed as colony diameter at 0.01 ug/plug after 3 days ( Rvb = 2.95 +/- 0.11 cm)2006Letters in applied microbiology, Aug, Volume: 43, Issue:2
Major secondary metabolites produced by two commercial Trichoderma strains active against different phytopathogens.
AID1090489Antimicrobial activity against Pythium ultimum assessed as colony diameter at 1 ug/plug after 3 days ( Rvb = 8.50 cm)2006Letters in applied microbiology, Aug, Volume: 43, Issue:2
Major secondary metabolites produced by two commercial Trichoderma strains active against different phytopathogens.
AID1090490Antimicrobial activity against Pythium ultimum assessed as colony diameter at 0.1 ug/plug after 3 days ( Rvb = 8.50 cm)2006Letters in applied microbiology, Aug, Volume: 43, Issue:2
Major secondary metabolites produced by two commercial Trichoderma strains active against different phytopathogens.
AID1091694Antifungal activity against Phytophthora cinnamomi assessed as growth inhibition at 200 ug/plug2009Letters in applied microbiology, Jun, Volume: 48, Issue:6
Factors affecting the production of Trichoderma harzianum secondary metabolites during the interaction with different plant pathogens.
AID1090495Antimicrobial activity against Rhizoctonia solani assessed as colony diameter at 1 ug/plug after 3 days ( Rvb = 2.95 +/- 0.11 cm)2006Letters in applied microbiology, Aug, Volume: 43, Issue:2
Major secondary metabolites produced by two commercial Trichoderma strains active against different phytopathogens.
AID1090493Antimicrobial activity against Rhizoctonia solani assessed as colony diameter at 100 ug/plug after 3 days ( Rvb = 2.95 +/- 0.11 cm)2006Letters in applied microbiology, Aug, Volume: 43, Issue:2
Major secondary metabolites produced by two commercial Trichoderma strains active against different phytopathogens.
AID1090491Antimicrobial activity against Pythium ultimum assessed as colony diameter at 0.01 ug/plug after 3 days ( Rvb = 8.50 cm)2006Letters in applied microbiology, Aug, Volume: 43, Issue:2
Major secondary metabolites produced by two commercial Trichoderma strains active against different phytopathogens.
AID1090500Antimicrobial activity against Gaeumannomyces graminis var. tritici assessed as colony diameter at 10 ug/plug after 3 days ( Rvb = 1.40+/- 0.8 cm)2006Letters in applied microbiology, Aug, Volume: 43, Issue:2
Major secondary metabolites produced by two commercial Trichoderma strains active against different phytopathogens.
AID1090503Antimicrobial activity against Gaeumannomyces graminis var. tritici assessed as colony diameter at 0.01 ug/plug after 3 days ( Rvb = 1.40+/- 0.8 cm)2006Letters in applied microbiology, Aug, Volume: 43, Issue:2
Major secondary metabolites produced by two commercial Trichoderma strains active against different phytopathogens.
AID1090494Antimicrobial activity against Rhizoctonia solani assessed as colony diameter at 10 ug/plug after 3 days ( Rvb = 2.95 +/- 0.11 cm)2006Letters in applied microbiology, Aug, Volume: 43, Issue:2
Major secondary metabolites produced by two commercial Trichoderma strains active against different phytopathogens.
AID1090487Antimicrobial activity against Pythium ultimum assessed as colony diameter at 100 ug/plug after 3 days ( Rvb = 8.50 cm)2006Letters in applied microbiology, Aug, Volume: 43, Issue:2
Major secondary metabolites produced by two commercial Trichoderma strains active against different phytopathogens.
AID1090501Antimicrobial activity against Gaeumannomyces graminis var. tritici assessed as colony diameter at 1 ug/plug after 3 days ( Rvb = 1.40+/- 0.8 cm)2006Letters in applied microbiology, Aug, Volume: 43, Issue:2
Major secondary metabolites produced by two commercial Trichoderma strains active against different phytopathogens.
AID1091693Antifungal activity against Botryotinia fuckeliana assessed as growth inhibition at 200 ug/plug2009Letters in applied microbiology, Jun, Volume: 48, Issue:6
Factors affecting the production of Trichoderma harzianum secondary metabolites during the interaction with different plant pathogens.
AID1090496Antimicrobial activity against Rhizoctonia solani assessed as colony diameter at 0.1 ug/plug after 3 days ( Rvb = 2.95 +/- 0.11 cm)2006Letters in applied microbiology, Aug, Volume: 43, Issue:2
Major secondary metabolites produced by two commercial Trichoderma strains active against different phytopathogens.
AID1090499Antimicrobial activity against Gaeumannomyces graminis var. tritici assessed as colony diameter at 100 ug/plug after 3 days ( Rvb = 1.40+/- 0.8 cm)2006Letters in applied microbiology, Aug, Volume: 43, Issue:2
Major secondary metabolites produced by two commercial Trichoderma strains active against different phytopathogens.
AID1090488Antimicrobial activity against Pythium ultimum assessed as colony diameter at 10 ug/plug after 3 days ( Rvb = 8.50 cm)2006Letters in applied microbiology, Aug, Volume: 43, Issue:2
Major secondary metabolites produced by two commercial Trichoderma strains active against different phytopathogens.
AID1090492Antimicrobial activity against Rhizoctonia solani assessed as colony diameter at 200 ug/plug after 3 days ( Rvb = 2.95 +/- 0.11 cm)2006Letters in applied microbiology, Aug, Volume: 43, Issue:2
Major secondary metabolites produced by two commercial Trichoderma strains active against different phytopathogens.
AID1090502Antimicrobial activity against Gaeumannomyces graminis var. tritici assessed as colony diameter at 0.1 ug/plug after 3 days ( Rvb = 1.40+/- 0.8 cm)2006Letters in applied microbiology, Aug, Volume: 43, Issue:2
Major secondary metabolites produced by two commercial Trichoderma strains active against different phytopathogens.
AID1091695Antifungal activity against Leptosphaeria maculans isolate UWA P11 assessed as growth inhibition at 200 ug/plug2009Letters in applied microbiology, Jun, Volume: 48, Issue:6
Factors affecting the production of Trichoderma harzianum secondary metabolites during the interaction with different plant pathogens.
AID1090498Antimicrobial activity against Gaeumannomyces graminis var. tritici assessed as colony diameter at 200 ug/plug after 3 days ( Rvb = 1.40+/- 0.8 cm)2006Letters in applied microbiology, Aug, Volume: 43, Issue:2
Major secondary metabolites produced by two commercial Trichoderma strains active against different phytopathogens.
AID1090486Antimicrobial activity against Pythium ultimum assessed as colony diameter at 200 ug/plug after 3 days ( Rvb = 8.50 cm)2006Letters in applied microbiology, Aug, Volume: 43, Issue:2
Major secondary metabolites produced by two commercial Trichoderma strains active against different phytopathogens.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 20.47

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index20.47 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.63 (4.65)
Search Engine Demand Index15.26 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (20.47)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]