Compounds > gweicurculactone
Page last updated: 2024-09-25

gweicurculactone

Description

gweicurculactone: from Curcuma kwangsiensis; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID130117
CHEMBL ID4168534
MeSH IDM0172769

Synonyms (6)

Synonym
gweicurculactone
(8r)-1,5,8-trimethyl-7,8-dihydro-6h-azuleno[6,5-b]furan-2-one
123914-43-2
azuleno(6,5-b)furan-2(5h)-one, 6,7-dihydro-3,5,8-trimethyl-, (r)-
DTXSID50154143
CHEMBL4168534

Bioassays (3)

Assay IDTitleYearJournalArticle
AID1504878Antioxidant activity against H2O2-induced cell damage in rat PC12 cells assessed as cell viability at 1 uM after 24 hrs by MTT assay (Rvb = 64.34 +/- 1.02 %)2017Journal of natural products, 12-22, Volume: 80, Issue:12
Sesqui- and Diterpenoids from the Radix of Curcuma aromatica.
AID1504879Antioxidant activity against H2O2-induced cell damage in rat PC12 cells assessed as cell viability at 5 uM after 24 hrs by MTT assay (Rvb = 64.34 +/- 1.02 %)2017Journal of natural products, 12-22, Volume: 80, Issue:12
Sesqui- and Diterpenoids from the Radix of Curcuma aromatica.
AID1504880Antioxidant activity against H2O2-induced cell damage in rat PC12 cells assessed as cell viability at 10 uM after 24 hrs by MTT assay (Rvb = 64.34 +/- 1.02 %)2017Journal of natural products, 12-22, Volume: 80, Issue:12
Sesqui- and Diterpenoids from the Radix of Curcuma aromatica.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (20.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
d-alpha tocopherol[no description available]medium10alpha-tocopherolalgal metabolite;
antiatherogenic agent;
anticoagulant;
antioxidant;
antiviral agent;
EC 2.7.11.13 (protein kinase C) inhibitor;
immunomodulator;
micronutrient;
nutraceutical;
plant metabolite
procurcumenol[no description available]medium10sesquiterpenoid
guaiane[no description available]medium30sesquiterpene;
terpenoid fundamental parent
sesquiterpenes[no description available]medium40
furan[no description available]medium10furans;
mancude organic heteromonocyclic parent;
monocyclic heteroarene		carcinogenic agent;
hepatotoxic agent;
Maillard reaction product
ConditionIndicatedRelationship StrengthStudiesTrials
Inflammation0low10
Innate Inflammatory Response0low10