gelsedine profile

gelsedine: isolated from Gelsemium sp.; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Related Flora

Flora	Rank	Flora Definition	Family	Family Definition
Gelsemium	genus	A plant genus of the family LOGANIACEAE (classified by some botanists as Gelsemiaceae). The sometimes used common name of trumpet flower is also used for DATURA.[MeSH]	Gelsemiaceae	[no description available]

Cross-References

ID Source	ID
PubMed CID	251002
MeSH ID	M0377083

Synonyms (17)

Synonym
spiro[3h-indole-3,6]methano[1h]oxepino[4,3-b]pyrrol]-2(1h)-one, 2'-ethyl-2',3',3'a,4',8',8'a-hexahydro-1-methoxy-, [2'r-(2'.alpha.,3'.alpha.,3'a.beta.,6'.alpha.,7'.alpha.,8'a.beta.)]-
nsc-71050
NSC71050 ,
spiro[3h-indole-3,6]methano[1h]oxepino[4,3-b]pyrrol]-2(1h)-one, 2'-ethyl-2',3',3'a,4',8',8'a-hexahydro-1-methoxy-
gelsedine
ethyl-1'-methoxy-spiro[[?]-[?],3'-indoline]-2'-one
spiro[3h-indole-3,7'(6'h)-[3,6]methano[1h]oxepino[4,3-b]pyrrol]-2(1h)-one, 2'-ethyl-2',3',3'a,4',8',8'a-hexahydro-1-methoxy-
spiro[3h-indole-3,7'(6'h)-[3,6]methano[1h]oxepino[4,3-b]pyrrol]-2(1h)-one, 2'-ethyl-2',3',3'a,4',8',8'a-hexahydro-1-methoxy-, [2'r-(2'.alpha.,3'.alpha.,3'a.beta.,6'.alpha.,7'.alpha.,8'a.beta.)]-
7096-96-0
nsc 71050
(spiro(3h-indole-3,7'(6'h)-(3,6)methano(1h)oxepino(4,3-b)pyrrol)-2(1h)-one,) 2'-ethyl-2',3',3'a, 4',8',8'a-hexahydro-1-methoxy-
dihydrohumantenmine
LDBVYQSHIPCQPT-UHFFFAOYSA-N
[2'r-(2'.alpha.,3'.alpha.,3'a.beta.,6'.alpha.,7'.alpha.,8'a.beta.)]-2 '-ethyl-2',3',3'a,4',8',8'a-hexahydro-1-methoxyspiro[3h-indole-3,7'(6 'h)-[3,6]methano[1h]oxepino[4,3-b]pyrrol]-2(1h)-one
2'-ethyl-1-methoxy-2',3',3'a,4',8',8'a-hexahydro-1'h,6'h-spiro[indole-3,7'-[3,6]methanooxepino[4,3-b]pyrrol]-2(1h)-one
DTXSID70991259
6-ethyl-1'-methoxyspiro[10-oxa-5-azatricyclo[5.3.1.04,8]undecane-2,3'-indole]-2'-one

Research

Studies (7)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (28.57)	29.6817
2010's	3 (42.86)	24.3611
2020's	2 (28.57)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 13.04

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	13.04 (24.57)
Research Supply Index	2.08 (2.92)
Research Growth Index	5.12 (4.65)
Search Engine Demand Index	0.00 (26.88)
Search Engine Supply Index	0.00 (0.95)

This Compound (13.04)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	1 (14.29%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	6 (85.71%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes
2-oxindole 2-oxindole: RN given refers to parent cpd; structure. indolin-2-one : An indolinone carrying an oxo group at position 2.	2.15	1	gamma-lactam; indolinone
gelsemine gelsemine: from Gelsemium sempervirens; structure given in first source	3.31	1	indole alkaloid
vobasine vobasine: structure given in first source; RN given refers to parent cpd. vobasine : An indole alkaloid that is vobasan in which the bridgehead methyl group is substituted by a methoxycarbonyl group and an additional oxo substituent is present in the 3-position.	2.31	1

Condition	Relationship Strength	Studies
Carcinoma, Non-Small Cell Lung [description not available]	2.25	1
Cancer of Lung [description not available]	2.25	1
Carcinoma, Non-Small-Cell Lung A heterogeneous aggregate of at least three distinct histological types of lung cancer, including SQUAMOUS CELL CARCINOMA; ADENOCARCINOMA; and LARGE CELL CARCINOMA. They are dealt with collectively because of their shared treatment strategy.	2.25	1
Lung Neoplasms Tumors or cancer of the LUNG.	2.25	1

gelsedine

Description