Compounds > fusarielin a
Page last updated: 2024-11-12

fusarielin a

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

fusarielin A: obtained from a Fusarium sp.; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID10453753
CHEMBL ID228444
MeSH IDM0243345

Synonyms (5)

Synonym
CHEMBL228444
fusarielin a
162341-17-5
DTXSID201017593
(2s,3s,4e,6e)-7-[(1r,2s,4r,5r,6s,7s,9s,11r)-5-[(e)-but-2-en-2-yl]-4,11-dimethyl-3,10-dioxatetracyclo[5.5.0.02,4.09,11]dodecan-6-yl]-2,4-dimethylhepta-4,6-diene-1,3-diol
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (6)

Assay IDTitleYearJournalArticle
AID566766Antibacterial activity against multidrug-resistant Staphylococcus aureus CCARM 3089 after 18 hrs by broth dilution method2010Journal of natural products, Dec-27, Volume: 73, Issue:12
Induced production of bromomethylchlamydosporols A and B from the marine-derived fungus Fusarium tricinctum.
AID291405Antibacterial activity against Staphylococcus aureus after 18 hrs by dilution method2007Journal of natural products, Jul, Volume: 70, Issue:7
Dehydroxychlorofusarielin B, an antibacterial polyoxygenated decalin derivative from the marine-derived fungus Aspergillus sp.
AID291407Antibacterial activity against multidrug-resistant Staphylococcus aureus after 18 hrs by dilution method2007Journal of natural products, Jul, Volume: 70, Issue:7
Dehydroxychlorofusarielin B, an antibacterial polyoxygenated decalin derivative from the marine-derived fungus Aspergillus sp.
AID566764Antibacterial activity against Staphylococcus aureus ATCC 29213 after 18 hrs by broth dilution method2010Journal of natural products, Dec-27, Volume: 73, Issue:12
Induced production of bromomethylchlamydosporols A and B from the marine-derived fungus Fusarium tricinctum.
AID566765Antibacterial activity against methicillin-resistant Staphylococcus aureus CCARM 3167 after 18 hrs by broth dilution method2010Journal of natural products, Dec-27, Volume: 73, Issue:12
Induced production of bromomethylchlamydosporols A and B from the marine-derived fungus Fusarium tricinctum.
AID291406Antibacterial activity against methicillin-resistant Staphylococcus aureus after 18 hrs by dilution method2007Journal of natural products, Jul, Volume: 70, Issue:7
Dehydroxychlorofusarielin B, an antibacterial polyoxygenated decalin derivative from the marine-derived fungus Aspergillus sp.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (8)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's3 (37.50)29.6817
2010's4 (50.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.73

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.73 (24.57)
Research Supply Index2.20 (2.92)
Research Growth Index4.93 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.73)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (12.50%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (87.50%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
coumarin
2H-chromen-2-one: coumarin derivative		2.0410coumarinsfluorescent dye;
human metabolite;
plant metabolite
decalin
decalin: RN given refers to cpd without isomeric designation; don't confuse with decaline which has a nitrogen at the juncture of the two rings;. trans-decalin : The trans-stereoisomer of decalin.. decalin : An ortho-fused bicyclic hydrocarbon that is the decahydro- derivative of naphthalene.		2.0310ortho-fused bicyclic hydrocarbonsolvent
warfarin
Warfarin: An anticoagulant that acts by inhibiting the synthesis of vitamin K-dependent coagulation factors. Warfarin is indicated for the prophylaxis and/or treatment of venous thrombosis and its extension, pulmonary embolism, and atrial fibrillation with embolization. It is also used as an adjunct in the prophylaxis of systemic embolism after myocardial infarction. Warfarin is also used as a rodenticide.. warfarin : A racemate comprising equal amounts of (R)- and (S)-warfarin. Extensively used as both an anticoagulant drug and as a pesticide against rats and mice.. 4-hydroxy-3-(3-oxo-1-phenylbutyl)-1-benzopyran-2-one : A member of the class of coumarins that is 4-hydroxycoumarin which is substituted at position 3 by a 1-phenyl-3-oxo-1-butyl group.		2.0410benzenes;
hydroxycoumarin;
methyl ketone
ConditionIndicatedRelationship StrengthStudiesTrials
Cancer of Ovary
[description not available]		02.1510
Ovarian Neoplasms
Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.		02.1510