Compounds > fumonisin a1

Page last updated: 2024-12-11

fumonisin a1

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

fumonisin A1: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	5486176
CHEBI ID	184800
MeSH ID	M0244482

Synonyms (11)

Synonym
fumonisin a1
(2r)-2-[2-[(5r,6r,7s,9s,11r,16s,18r,19r)-19-acetamido-6-[(3r)-3,4-dicarboxybutanoyl]oxy-11,16,18-trihydroxy-5,9-dimethylicosan-7-yl]oxy-2-oxoethyl]butanedioic acid
117415-48-2
CHEBI:184800
unii-ta422003jx
1,1'-(1-(12-acetylamino-4,9,11-trihydroxy-2-methyltridecyl)-2-(1-methylpentyl)-1,2-ethanediyl) 1,2,3-propanetricarboxylate
1,2,3-propanetricarboxylic acid, 1,1'-(1-((2s,4r,9r,11s,12s)-12-acetylamino-4,9,11-trihydroxy-2-methyltridecyl)-2-((1r)-1-methylpentyl)-1,2-ethanediyl) ester, (2r,2'r)-
ta422003jx ,
1,2,3-propanetricarboxylic acid, 1,1'-(1-((2s,4r,9r,11s,12s)-12- acetylamino-4,9,11-trihydroxy-2-methyltridecyl)-2-((1r)-1-methylpentyl)-1,2-ethanediyl) ester,(2r,2'r)-
DTXSID40151782
Q27289864

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

Class	Description
fumonisin	A family of toxins produced by several species of Fusarium moulds which occur mainly in maize.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (6)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	2 (33.33)	18.2507
2000's	3 (50.00)	29.6817
2010's	1 (16.67)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.36

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	12.36 (24.57)
Research Supply Index	1.95 (2.92)
Research Growth Index	4.31 (4.65)
Search Engine Demand Index	0.00 (26.88)
Search Engine Supply Index	0.00 (0.95)

This Compound (12.36)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	1 (16.67%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	5 (83.33%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Trials	Classes	Roles
aminopentol aminopentol: metabolite of fumonisin B1	1.99	1	0
fumonisin b1 fumonisin B1: isolated from Fusarium moniliforme MRC 826; structure given in first source; has cancer-promoting activity; inhibits ceramide synthase. fumonisin B1 : A diester that results from the condensation of the 1-carboxy groups of two molecules of propane-1,2,3-tricarboxylic acid with hydroxy groups at positions 14 and 15 of (2S,3S,5R,10R,12S,14S,15R,16R)-2-amino-12,16-dimethylicosane-3,5,10,14,15-pentol.	4.02	4	0	diester; fumonisin; primary amino compound; triol	carcinogenic agent; metabolite
fumonisin b2 fumonisin B2: produced by Fusarium moniliforme MRC 826; structure given in first source; has cancer-promoting ability. fumonisin B2 : A fumonisin that is (2S,3S,12S,14S,15R,16R)-2-amino-12,16-dimethylicosane-3,14,15-triol in which the hydroxy groups at positions 14 and 15 have each been esterified by condensation with the 1-carboxy group of 3-carboxyglutaric acid (giving a 3-carboxyglutarate ester group with R configuration in each case).	3.81	3	0	diester; diol; fumonisin; primary amino compound	Aspergillus metabolite; carcinogenic agent
safingol safingol: RN given refers to the (R-(R,S))-isomer	2.41	2	0	amino alcohol
sphingosine sphing-4-enine : A sphingenine in which the C=C double bond is located at the 4-position.. sphingenine : A 2-aminooctadecene-1,3-diol having (2S,3R)-configuration.. sphingoid : Sphinganine, its homologs and stereoisomers, and the hydroxy and unsaturated derivatives of these compounds.. 2-aminooctadec-4-ene-1,3-diol : A 2-aminooctadecene-1,3-diol having its double bond at position 4.	2.41	2	0	sphing-4-enine	human metabolite; mouse metabolite
fumonisin b4 fumonisin B4: from Fusarium moniliforme; has cancer-promoting activity. fumonisin B4 : A fumonisin that is fumonisin B2 that is lacking hydroxy group located gamma- to the amino substituent.	3.08	1	0	diester; fumonisin; primary amino compound; secondary alcohol	Aspergillus metabolite
fumonisin b3 fumonisin B3: structure given in first source; produced by Fusarium moniliforme	3.52	2	0

Condition	Indicated	Relationship Strength	Studies	Trials
Deficiency, Folic Acid [description not available]	0	2.01	1	0
Folic Acid Deficiency A nutritional condition produced by a deficiency of FOLIC ACID in the diet. Many plant and animal tissues contain folic acid, abundant in green leafy vegetables, yeast, liver, and mushrooms but destroyed by long-term cooking. Alcohol interferes with its intermediate metabolism and absorption. Folic acid deficiency may develop in long-term anticonvulsant therapy or with use of oral contraceptives. This deficiency causes anemia, macrocytic anemia, and megaloblastic anemia. It is indistinguishable from vitamin B 12 deficiency in peripheral blood and bone marrow findings, but the neurologic lesions seen in B 12 deficiency do not occur. (Merck Manual, 16th ed)	0	2.01	1	0
Cerebromalacia [description not available]	0	2.9	1	0
Equine Diseases [description not available]	0	2.9	1	0
Poultry Diseases Diseases of birds which are raised as a source of meat or eggs for human consumption and are usually found in barnyards, hatcheries, etc. The concept is differentiated from BIRD DISEASES which is for diseases of birds not considered poultry and usually found in zoos, parks, and the wild.	0	2.9	1	0
Edema, Pulmonary [description not available]	0	2.9	1	0
Swine Diseases Diseases of domestic swine and of the wild boar of the genus Sus.	0	2.9	1	0
Poisoning Used with drugs, chemicals, and industrial materials for human or animal poisoning, acute or chronic, whether the poisoning is accidental, occupational, suicidal, by medication error, or by environmental exposure.	0	2.9	1	0
Pulmonary Edema Excessive accumulation of extravascular fluid in the lung, an indication of a serious underlying disease or disorder. Pulmonary edema prevents efficient PULMONARY GAS EXCHANGE in the PULMONARY ALVEOLI, and can be life-threatening.	0	2.9	1	0