Compounds > formaldehydesulfoxylate
Page last updated: 2024-11-05

formaldehydesulfoxylate

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Formaldehydesulfoxylate, also known as Rongalite, is a reducing agent used in various industrial applications, including textile dyeing, leather tanning, and papermaking. It is typically synthesized by reacting formaldehyde with sodium bisulfite. The compound acts as a reducing agent due to the presence of the sulfoxylate group (-SO2H), which can donate electrons to other molecules. It is studied for its effectiveness in reducing various chemical species, including dyes, metal ions, and organic pollutants. The use of formaldehydesulfoxylate in textile dyeing, for instance, helps in removing excess dye and improving colorfastness. However, concerns regarding its potential toxicity have led to research exploring alternative reducing agents for industrial applications. '

formaldehydesulfoxylate: antidote for mercury poisoning; RN given refers to parent cpd; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID9000
CHEMBL ID2111064
MeSH IDM0057156

Synonyms (18)

Synonym
NCIOPEN2_000709
hydroxymethanesulfinic acid
formaldehydesulfoxylate
79-25-4
einecs 201-189-4
unii-m049n73196
m049n73196 ,
hydroxymethanesulphinic acid
hydroxymethanesulfinic acid, monosodium salt
methanesulfinic acid,hydroxy- (8ci,9ci)
SBGKURINHGJRFN-UHFFFAOYSA-N
DTXSID7048083
CHEMBL2111064
formaldehyde sulfinic acid
formaldehydsulfoxylsaure
Q27283285
STARBLD0012097
EN300-7570943
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (9)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (22.22)18.7374
1990's1 (11.11)18.2507
2000's0 (0.00)29.6817
2010's3 (33.33)24.3611
2020's3 (33.33)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 44.09

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index44.09 (24.57)
Research Supply Index2.30 (2.92)
Research Growth Index4.59 (4.65)
Search Engine Demand Index61.70 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (44.09)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other9 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
formic acid
formic acid: RN given refers to parent cpd. formic acid : The simplest carboxylic acid, containing a single carbon. Occurs naturally in various sources including the venom of bee and ant stings, and is a useful organic synthetic reagent. Principally used as a preservative and antibacterial agent in livestock feed. Induces severe metabolic acidosis and ocular injury in human subjects.		210monocarboxylic acidantibacterial agent;
astringent;
metabolite;
protic solvent;
solvent
formaldehyde
paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy		2.3320aldehyde;
one-carbon compound		allergen;
carcinogenic agent;
disinfectant;
EC 3.5.1.4 (amidase) inhibitor;
environmental contaminant;
Escherichia coli metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
procaine
Procaine: A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016).. procaine : A benzoate ester, formally the result of esterification of 4-aminobenzoic acid with 2-diethylaminoethanol but formed experimentally by reaction of ethyl 4-aminobenzoate with 2-diethylaminoethanol.		6.9310benzoate ester;
substituted aniline;
tertiary amino compound		central nervous system depressant;
drug allergen;
local anaesthetic;
peripheral nervous system drug
3-hydroxybutanal
[no description available]		2.4110
cellobiose
beta-cellobiose : A cellobiose with beta configuration at the reducing-end glucose residue.		2.110cellobioseepitope
sodium sulfate
[no description available]		210inorganic sodium salt
alkenes
[no description available]		2.4110
quinone methide
quinone methide: intermediate in eumelanin biosynthesis; structure given in first source. quinomethane : A methylidenecyclohexadienone, formally derived from a benzoquinone by replacement of one of the quinone oxygens by a methylidene group.		2.4110quinomethane
2-oxindole
2-oxindole: RN given refers to parent cpd; structure. indolin-2-one : An indolinone carrying an oxo group at position 2.		2.4110gamma-lactam;
indolinone
glycosides
[no description available]		2.110
arsenic
Arsenic: A shiny gray element with atomic symbol As, atomic number 33, and atomic weight 75. It occurs throughout the universe, mostly in the form of metallic arsenides. Most forms are toxic. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), arsenic and certain arsenic compounds have been listed as known carcinogens. (From Merck Index, 11th ed)		1.9310metalloid atom;
pnictogen		micronutrient
ConditionIndicatedRelationship StrengthStudiesTrials