Page last updated: 2024-11-08

fomannoxin

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

fomannoxin: from Heterobasidion annosum; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID163013
CHEMBL ID4099389
MeSH IDM0223672

Synonyms (8)

Synonym
fomannoxin
63587-64-4
5-benzofurancarboxaldehyde, 2,3-dihydro-2-(1-methylethenyl)-
2,3-dihydro-2-(1-methylethenyl)-5-benzofurancarboxaldehyde
Z1511751448
DTXSID60979804
2-(prop-1-en-2-yl)-2,3-dihydro-1-benzofuran-5-carbaldehyde
CHEMBL4099389

Research Excerpts

Overview

Fomannoxin is a biologically active benzohydrofuran. It has been suggested to be involved in the pathogenicity of the root rotting fungus Heterobasidion annosum sensu lato.

ExcerptReferenceRelevance
"Fomannoxin is a biologically active benzohydrofuran, which has been suggested to be involved in the pathogenicity of the root rotting fungus Heterobasidion annosum sensu lato. "( Biosynthesis of fomannoxin in the root rotting pathogen Heterobasidion occidentale.
Broberg, A; Hansson, D; Karlsson, M; Menkis, A; Olson, K; Stenlid, J, 2012
)
2.17
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (2)

Assay IDTitleYearJournalArticle
AID1437648Inhibition of LPS-induced COX-2 expression in mouse BV2 cells at 20 uM pretreated for 15 mins followed by LPS-stimulation after 24 hrs by western blot analysis relative to control2017Journal of natural products, 01-27, Volume: 80, Issue:1
Bioactive Constituents from the Termite Nest-Derived Medicinal Fungus Xylaria nigripes.
AID1437647Inhibition of LPS-induced iNOS expression in mouse BV2 cells at 20 uM pretreated for 15 mins followed by LPS-stimulation after 24 hrs by western blot analysis relative to control2017Journal of natural products, 01-27, Volume: 80, Issue:1
Bioactive Constituents from the Termite Nest-Derived Medicinal Fungus Xylaria nigripes.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's3 (42.86)18.2507
2000's0 (0.00)29.6817
2010's4 (57.14)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]