Page last updated: 2024-12-06

ethylene thiuram monosulfide

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Ethylene thiuram monosulfide (ETMS) is a sulfur-containing organic compound used as a vulcanization accelerator in the rubber industry. It is synthesized by reacting ethylene diamine with carbon disulfide and then reacting the resulting dithiocarbamate with sulfur. ETMS is a highly effective accelerator, resulting in rapid vulcanization and improved physical properties of rubber. It is also used as a fungicide and bactericide in agriculture. The compound is known to be a skin irritant and can cause allergic reactions. Studies are ongoing to better understand its environmental fate and potential for bioaccumulation.'

ethylene thiuram monosulfide: breakdown product of ethylenebisdithiocarbamate; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID36603
SCHEMBL ID28975
MeSH IDM0055442

Synonyms (42)

Synonym
ethylenebis(thiocarbamyl) sulfide
hortocritt
ccris 7251
vegita
ethylene thiuram monosulphide
ethylene bisthiuram monosulfide
etm (heterocycle)
3h-imidazo(2,1-c)-1,2,4-dithiazole-3-thione, 5,6-dihydro-
epa pesticide chemical code 481200
einecs 251-684-4
brn 0006205
ethylene thiuram monosulfide
endodan 50 wp
n,n'-dimethylene-5-imino-1,2-dithio-4-azolidine-3-thione
thiuram monosulfide, 1,2-ethanediyl-
ethylenebisdiisothiocyanato sulfide
ethylenethiocarbamyl sulfide
etem
n,n'-ethylenebis(thiocarbamoyl)sulfide
endodan
ethylenethiuram monosulfide
caswell no. 481a
hexahydro-2,7-dithio-1,3,6-thiadiazepine
ethylenethiuram sulfide
5,6-dihydro-3h-imidazo(2,1-c)-1,2,4-dithiazole-3-thione
etem [bsi]
5,6-dihydroimidazo[2,1-c][1,2,4]dithiazole-3-thione
AKOS006271825
unii-ng03351c2t
4-27-00-08745 (beilstein handbook reference)
33813-20-6
ng03351c2t ,
CK-0237
3h,5h,6h-imidazo[2,1-c][1,2,4]dithiazole-3-thione
ethylenebis(thiocarbamyl) sulphide
SCHEMBL28975
DTXSID70187473
5,6-dihydro-3h-imidazo[2,1-c]-1,2,4-dithiazole-3-thione
3h-imidazo[2,1-c]-1,2,4-dithiazole-3-thione, 5,6-dihydro-
mancozeb tp3
ethylene bisisothiocyanate sulphide
Q27284850

Research Excerpts

Toxicity

ExcerptReferenceRelevance
" A low teratogenic and embryotoxic activity was established after a single treatment with I/2 LD50 on 13 th gestation day."( [Experimental study of the teratogenicity and embryotoxicity of endodan].
Vergieva, T, 1984
)
0.27
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19907 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.37

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.37 (24.57)
Research Supply Index2.08 (2.92)
Research Growth Index4.45 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.37)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]