ethinyl estradiol glucuronide profile

ID Source	ID
PubMed CID	165365482
MeSH ID	M0083553

ID Source

PubMed CID

165365482

MeSH ID

M0083553

Synonym
ethinyl estradiol glucuronide
86571-05-3
DTXSID501043717

Synonym

ethinyl estradiol glucuronide

86571-05-3

DTXSID501043717

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	4 (50.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	3 (37.50)	29.6817
2010's	1 (12.50)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, This Drug (%)

All Drugs %

pre-1990

4 (50.00)

18.7374

1990's

0 (0.00)

18.2507

2000's

3 (37.50)

29.6817

2010's

1 (12.50)

24.3611

2020's

0 (0.00)

2.80

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	8 (100.00%)	84.16%

Publication Type

This drug (%)

All Drugs (%)

Trials

0 (0.00%)

5.53%

Reviews

0 (0.00%)

6.00%

Case Studies

0 (0.00%)

4.05%

Observational

0 (0.00%)

0.25%

Other

8 (100.00%)

84.16%

Substance	Studies	Classes	Roles	First Year	Last Year	Average Age	Relationship Strength	pre-1990	2000's	2010's
estriol	1	16alpha-hydroxy steroid; 17beta-hydroxy steroid; 3-hydroxy steroid	estrogen; human metabolite; human xenobiotic metabolite; mouse metabolite	1984	1984	40.0	low	1	0	0
ethinyl estradiol	8	17-hydroxy steroid; 3-hydroxy steroid; terminal acetylenic compound	xenoestrogen	1980	2011	29.6	high	4	3	1
uridine	1	uridines	drug metabolite; fundamental metabolite; human metabolite	2006	2006	18.0	low	0	1	0
taurocholic acid	1	amino sulfonic acid; bile acid taurine conjugate	human metabolite	1984	1984	40.0	low	1	0	0
dihydrotestosterone	1	17beta-hydroxy steroid; 17beta-hydroxyandrostan-3-one; 3-oxo-5alpha-steroid	androgen; Daphnia magna metabolite; human metabolite; mouse metabolite	1984	1984	40.0	low	1	0	0
uridine diphosphate glucuronic acid	1	UDP-D-glucuronic acid	Escherichia coli metabolite; human metabolite; mouse metabolite	2006	2006	18.0	low	0	1	0
galactosamine	1	D-galactosamine; primary amino compound	toxin	2006	2006	18.0	low	0	1	0
ethinylestradiol-3-sulfate	3	17beta-hydroxy steroid; steroid sulfate	antineoplastic agent; estrogen	2004	2011	17.7	high	0	2	1
estriol glucuronide	1			1984	1984	40.0	medium	1	0	0
taurochenodeoxycholic acid	1	bile acid taurine conjugate	human metabolite; mouse metabolite	2006	2006	18.0	low	0	1	0
ursodoxicoltaurine	1	bile acid taurine conjugate	anti-inflammatory agent; apoptosis inhibitor; bone density conservation agent; cardioprotective agent; human metabolite; neuroprotective agent	2006	2006	18.0	low	0	1	0
dihydrotestosterone glucuronide	1	3-oxo-5alpha-steroid; steroid glucosiduronic acid	human urinary metabolite	1984	1984	40.0	medium	1	0	0

Substance

Studies

Classes

Roles

First Year

Last Year

Average Age

Relationship Strength

Trials

pre-1990

1990's

2000's

2010's

post-2020

estriol

16alpha-hydroxy steroid;
17beta-hydroxy steroid;
3-hydroxy steroid

estrogen;
human metabolite;
human xenobiotic metabolite;
mouse metabolite

1984

40.0

low

ethinyl estradiol

17-hydroxy steroid;
3-hydroxy steroid;
terminal acetylenic compound

xenoestrogen

1980

2011

29.6

high

uridine

uridines

drug metabolite;
fundamental metabolite;
human metabolite

2006

18.0

low

taurocholic acid

amino sulfonic acid;
bile acid taurine conjugate

human metabolite

1984

40.0

low

dihydrotestosterone

17beta-hydroxy steroid;
17beta-hydroxyandrostan-3-one;
3-oxo-5alpha-steroid

androgen;
Daphnia magna metabolite;
human metabolite;
mouse metabolite

1984

40.0

low

uridine diphosphate glucuronic acid

UDP-D-glucuronic acid

Escherichia coli metabolite;
human metabolite;
mouse metabolite

2006

18.0

low

galactosamine

D-galactosamine;
primary amino compound

toxin

2006

18.0

low

ethinylestradiol-3-sulfate

17beta-hydroxy steroid;
steroid sulfate

antineoplastic agent;
estrogen

2004

2011

17.7

high

estriol glucuronide

1984

40.0

medium

taurochenodeoxycholic acid

bile acid taurine conjugate

human metabolite;
mouse metabolite

2006

18.0

low

ursodoxicoltaurine

bile acid taurine conjugate

anti-inflammatory agent;
apoptosis inhibitor;
bone density conservation agent;
cardioprotective agent;
human metabolite;
neuroprotective agent

2006

18.0

low

dihydrotestosterone glucuronide

3-oxo-5alpha-steroid;
steroid glucosiduronic acid

human urinary metabolite

1984

40.0

medium

Condition	Indicated	Studies	First Year	Last Year	Average Age	Relationship Strength	Trials	pre-1990	1990's	2000's	2010's	post-2020
Bile Duct Obstruction	0	3	1983	2006	33.0	high	0	2	0	1	0	0
Cholestasis	0	3	1983	2006	33.0	high	0	2	0	1	0	0

Condition

Indicated

Studies

First Year

Last Year

Average Age

Relationship Strength

Trials

pre-1990

1990's

2000's

2010's

post-2020

Bile Duct Obstruction

1983

2006

33.0

high

Cholestasis

1983

2006

33.0

high

Galactosamine prevents ethinylestradiol-induced cholestasis.
Drug metabolism and disposition: the biological fate of chemicals, , Volume: 34, Issue:6, 2006

Characterization of the interaction between estrogen metabolites and taurocholate for uptake into isolated hepatocytes. Lack of correlation between cholestasis and inhibition of taurocholate uptake.
Journal of steroid biochemistry, , Volume: 20, Issue:5, 1984

Ethynylestradiol-17 beta D-ring glucuronide conjugates are potent cholestatic agents in the rat.
Life sciences, , Jun-27, Volume: 32, Issue:26, 1983

Article	Year
Efflux transport is an important determinant of ethinylestradiol glucuronide and ethinylestradiol sulfate pharmacokinetics. Drug metabolism and disposition: the biological fate of chemicals, , Volume: 39, Issue:10	2011
The pharmacokinetics of a large (3 mg) oral dose of ethynylestradiol in women. Contraception, , Volume: 21, Issue:2	1980

Article

Year

Efflux transport is an important determinant of ethinylestradiol glucuronide and ethinylestradiol sulfate pharmacokinetics.
Drug metabolism and disposition: the biological fate of chemicals, , Volume: 39, Issue:10

2011

The pharmacokinetics of a large (3 mg) oral dose of ethynylestradiol in women.
Contraception, , Volume: 21, Issue:2

1980

Article	Year
The pharmacokinetics of a large (3 mg) oral dose of ethynylestradiol in women. Contraception, , Volume: 21, Issue:2	1980

Article

Year

The pharmacokinetics of a large (3 mg) oral dose of ethynylestradiol in women.
Contraception, , Volume: 21, Issue:2

1980

ethinyl estradiol glucuronide

Description

Cross-References

Synonyms (3)

Research

Studies (8)

Study Types

Pharmacokinetics (2)

Dosage (1)

ethinyl estradiol glucuronide

Description

Cross-References

Synonyms (3)

Research

Studies (8)

Study Types

Related Drugs (12)

Drugs Researched Together (12)

Related Conditions (2)

Pharmacokinetics (2)

Dosage (1)