Compounds > epsilon-decalactone
Page last updated: 2024-12-06

epsilon-decalactone

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Epsilon-decalactone, also known as δ-decalactone, is a naturally occurring lactone with a sweet, fruity, and coconut-like aroma. It is found in various fruits and flowers, including peaches, apples, and jasmine. Epsilon-decalactone is used as a fragrance ingredient in perfumes, cosmetics, and food products. It is also used in flavorings and as a solvent. Epsilon-decalactone is typically synthesized via chemical reactions involving various starting materials, such as cyclohexanone and 1,4-butanediol. It is known for its pleasant aroma and its ability to contribute to the sweetness and complexity of fragrance and flavor profiles. Research on epsilon-decalactone has focused on its synthesis, its application in various industries, and its potential use as a biofuel. The compound has been shown to have promising properties for use as a renewable fuel source, further enhancing its significance in the field of sustainable energy.'

Cross-References

ID SourceID
PubMed CID62583
CHEMBL ID3185668
CHEBI ID180234
SCHEMBL ID192113
MeSH IDM0148267

Synonyms (36)

Synonym
CHEBI:180234
5579-78-2
6-decanolide
einecs 226-963-9
7-butyl-2-oxepanone
7-butyloxepan-2-one
2-oxepanone, 7-butyl-
brn 0117541
6-hydroxydecanoic acid epsilon-lactone
6-butylhexanolide
fema no. 3613
epsilon-decalactone
epsilon-decalactone, >=99%
FT-0693270
dtxsid8047551 ,
NCGC00256889-01
dtxcid6027551
cas-5579-78-2
tox21_302462
662w32kl4o ,
5-17-09-00089 (beilstein handbook reference)
unii-662w32kl4o
.epsilon.-decalactone, (+/-)-
.epsilon.-decalactone
.epsilon.-decalactone [fhfi]
6-hydroxydecanoic acid .epsilon.-lactone
2-oxepanone, 7-butyl
(+/-)-.epsilon.-decalactone
SCHEMBL192113
e-decalactone
YKVIWISPFDZYOW-UHFFFAOYSA-N
6-butylhexan-6-olide
CHEMBL3185668
7-butyl-2-oxepanone, 9ci, 8ci
fema 3613
Q27263941

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
" Physicochemical properties, biodegradability, and biocompatibility of the polymers, and evaluations in vitro and in vivo of specific dosage forms using the polymers, are included."( Poly(hydroxy acids) in drug delivery.
Juni, K; Nakano, M, 1987)		0.27
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
lactoneAny cyclic carboxylic ester containing a 1-oxacycloalkan-2-one structure, or an analogue having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (2)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
peroxisome proliferator-activated receptor deltaHomo sapiens (human)Potency59.37490.001024.504861.6448AID743212; AID743227
peroxisome proliferator activated receptor gammaHomo sapiens (human)Potency37.43540.001019.414170.9645AID743140
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (16.67)18.7374
1990's1 (16.67)18.2507
2000's0 (0.00)29.6817
2010's2 (33.33)24.3611
2020's2 (33.33)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 23.30

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index23.30 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.66 (4.65)
Search Engine Demand Index21.17 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (23.30)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (16.67%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (83.33%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
lactic acid
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed). 2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.		3.06102-hydroxy monocarboxylic acidalgal metabolite;
Daphnia magna metabolite
glycolic acid
glycolic acid: RN given refers to parent cpd. glycolic acid : A 2-hydroxy monocarboxylic acid that is acetic acid where the methyl group has been hydroxylated.		3.06102-hydroxy monocarboxylic acid;
primary alcohol		keratolytic drug;
metabolite
1,1,1-trichloroethane
Trichloroethanes: Chlorinated ethanes which are used extensively as industrial solvents. They have been utilized in numerous home-use products including spot remover preparations and inhalant decongestant sprays. These compounds cause central nervous system and cardiovascular depression and are hepatotoxic. Include 1,1,1- and 1,1,2-isomers.. 1,1,1-trichloroethane : A member of the class of chloroethanes carrying three chloro substituents at position 1.		6.9810chloroethanespolar solvent
isoprene
isoprene: used in manufacture of ''synthetic'' rubber, butyl rubber; copolymer in production of elastomers; structure. isoprene : A hemiterpene with the formula CH2=C(CH3)CH=CH2; the monomer of natural rubber and a common structure motif to the isoprenoids, a large class of other naturally occurring compounds.		2.0810alkadiene;
hemiterpene;
volatile organic compound		plant metabolite
dilactide
dilactide: structure given in first source		2.0810dioxanes
caprolactone
hexano-6-lactone : A epsilon-lactone that is oxepane substituted by an oxo group at position 2.		2.0810epsilon-lactone
delta-valerolactone
[no description available]		3.0610delta-lactone
indium
Indium: A metallic element, atomic number 49, atomic weight 114.818, symbol In. It is named from its blue line in the spectrum.. indium atom : A metallic element first identified and named from the brilliant indigo (Latin indicum) blue line in its flame spectrum.		2.4110boron group element atom
ConditionIndicatedRelationship StrengthStudiesTrials