| Assay ID | Title | Year | Journal | Article |
|---|
| AID1347411 | qHTS to identify inhibitors of the type 1 interferon - major histocompatibility complex class I in skeletal muscle: primary screen against the NCATS Mechanism Interrogation Plate v5.0 (MIPE) Libary | 2020 | ACS chemical biology, 07-17, Volume: 15, Issue:7
| High-Throughput Screening to Identify Inhibitors of the Type I Interferon-Major Histocompatibility Complex Class I Pathway in Skeletal Muscle. |
| AID466494 | Inhibition of human KHC at 10 uM | 2010 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 20, Issue:5
| The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5. |
| AID466492 | Inhibition of human MCAK at 1 uM | 2010 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 20, Issue:5
| The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5. |
| AID466477 | Antitumor activity against human COLO205 cells xenografted in mouse assessed as tumor growth inhibition at 15 mg/kg, ip administered twice weekly relative to control | 2010 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 20, Issue:5
| The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5. |
| AID466490 | Inhibition of human KIFC3 at 1 uM | 2010 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 20, Issue:5
| The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5. |
| AID466478 | Antitumor activity against human COLO205 cells xenografted in mouse assessed as tumor growth inhibition at 30 mg/kg, ip administered twice weekly relative to control | 2010 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 20, Issue:5
| The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5. |
| AID466487 | Inhibition of human chromokinesin at 1 uM | 2010 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 20, Issue:5
| The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5. |
| AID466499 | Inhibition of human chromokinesin at 10 uM | 2010 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 20, Issue:5
| The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5. |
| AID466481 | Clearance in mouse | 2010 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 20, Issue:5
| The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5. |
| AID466486 | Inhibition of human CENPE at 1 uM | 2010 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 20, Issue:5
| The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5. |
| AID466476 | Antiproliferative activity against human HCT116 cells after 48 hrs by crystal violet staining assay | 2010 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 20, Issue:5
| The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5. |
| AID466484 | Bioavailability in mouse at >10 mg/kg | 2010 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 20, Issue:5
| The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5. |
| AID466489 | Inhibition of human KIF3C at 1 uM | 2010 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 20, Issue:5
| The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5. |
| AID466496 | Inhibition of human KIFC3 at 10 uM | 2010 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 20, Issue:5
| The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5. |
| AID466483 | Half life in mouse | 2010 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 20, Issue:5
| The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5. |
| AID466479 | Toxicity in mouse assessed as body weight loss at 15 mg/kg, ip administered twice weekly | 2010 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 20, Issue:5
| The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5. |
| AID466498 | Inhibition of human CENPE at 10 uM | 2010 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 20, Issue:5
| The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5. |
| AID466485 | Inhibition of BimC at 1 uM | 2010 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 20, Issue:5
| The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5. |
| AID466480 | Toxicity in mouse assessed as body weight loss at 30 mg/kg, ip administered twice weekly | 2010 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 20, Issue:5
| The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5. |
| AID466482 | Volume of distribution in mouse | 2010 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 20, Issue:5
| The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5. |
| AID466493 | Inhibition of BimC at 10 uM | 2010 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 20, Issue:5
| The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5. |
| AID466488 | Inhibition of human KHC at 1 uM | 2010 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 20, Issue:5
| The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5. |
| AID466491 | Inhibition of human MKLP1 at 1 uM | 2010 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 20, Issue:5
| The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5. |
| AID466500 | Inhibition of human MKLP1 at 10 uM | 2010 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 20, Issue:5
| The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5. |
| AID466495 | Inhibition of human KIF3C at 10 uM | 2010 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 20, Issue:5
| The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5. |
| AID466475 | Inhibition of ATPase activity of human recombinant EG5 assessed as ATP hydrolysis by pyruvate kinase-lactate dehydrogenase coupled assay | 2010 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 20, Issue:5
| The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5. |
| AID466497 | Inhibition of human MCAK at 10 uM | 2010 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 20, Issue:5
| The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |