Page last updated: 2024-11-12
elaiomycin
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
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Protein Interactions
Research Growth
Market Indicators
Description
elaiomycin: naturally occurring azoxyalkene; RN given refers to cpd without isomeric designation; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 20054902 |
| CHEMBL ID | 2152468 |
| SCHEMBL ID | 16431330 |
| MeSH ID | M0062177 |
Synonyms (30)
| Synonym |
|---|
| nsc-88205 |
| elaiomycin |
| 23315-05-1 |
| d-threo-4-methoxy-3-(1-octenylazoxy)-2-butanol |
| 2-butanol, 4-methoxy-3-(1-octenyl-onn-azoxy)-, (e,z)-(2s,3s)- |
| d-threo-methoxy-3-(1-octenyl-onn-azoxy)-2-butanol |
| hsdb 5122 |
| (e,z)-(2s,3s)-4-methoxy-3-(1-octenyl-onn-azoxy)-2-butanol |
| (2s,3s)-4-methoxy-3-(1'-cis-octenyl-cis-azoxy)-2-butanol |
| 2-butanol, 4-methoxy-3-(1-octenyl-onn-azoxy)-, d-threo- |
| 2-butanol, 4-methoxy-1((n(e),1z)-1-octenyl-onn-azoxy)-, (2s,3s)- |
| nsc 88205 |
| 2-butanol, 4-methoxy-3-(1-octenyl-onn-azoxy)-, (s-(r*,r*-(e,z)))- |
| brn 2417343 |
| ACON1_001844 |
| NCGC00180084-01 |
| unii-227v1pl5tf |
| 227v1pl5tf , |
| CHEMBL2152468 |
| 2-butanol, 4-methoxy-3-((1z)-2-((1z)-1-octen-1-yl)-2-oxidodiazenyl)-, (2s,3s)- |
| 4-methoxy-3-(1-octenyl-onn-azoxy)-2-butanol, (e,z)-(2s,3s)- |
| elaiomycin [mi] |
| 4-methoxy-3-(1'-cis-octenyl-cis-azoxy)-2-butanol, (2s,3s)- |
| 2-butanol, 4-methoxy-3-((n(z),1z)-1-octenyl-onn-azoxy)-, (2s,3s)- |
| 2-butanol, 4-methoxy-3-(1-octenyl-onn-azoxy)-, (s-(r*,r*- (e,z)))- |
| elaiomycin, (+)- |
| 2-butanol, 4-methoxy-3-(1-octenyl-onn-azoxy)-, (s-(r*,r*-(z,z)))- |
| SCHEMBL16431330 |
| Q15410947 |
| DTXSID801028152 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Bioassays (29)
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID691996 | Antifungal activity against Penicillium notatum JP36 P1 assessed as zone of inhibition at 50 ug/disc after 24 hrs by agar diffusion assay | 2012 | Journal of natural products, Oct-26, Volume: 75, Issue:10 | Elaiomycins D-F, antimicrobial and cytotoxic azoxides from Streptomyces sp. strain HKI0708. |
| AID691981 | Cytotoxicity against human RXF 486L cells by propidium iodide-based fluorescence assay | 2012 | Journal of natural products, Oct-26, Volume: 75, Issue:10 | Elaiomycins D-F, antimicrobial and cytotoxic azoxides from Streptomyces sp. strain HKI0708. |
| AID691834 | Antifungal activity against Aspergillus fumigatus ATCC 46645 assessed as zone of inhibition at 50 ug/disc after 24 hrs by agar diffusion assay | 2012 | Journal of natural products, Oct-26, Volume: 75, Issue:10 | Elaiomycins D-F, antimicrobial and cytotoxic azoxides from Streptomyces sp. strain HKI0708. |
| AID691975 | Cytotoxicity against human MAXF 401NL cells by propidium iodide-based fluorescence assay | 2012 | Journal of natural products, Oct-26, Volume: 75, Issue:10 | Elaiomycins D-F, antimicrobial and cytotoxic azoxides from Streptomyces sp. strain HKI0708. |
| AID691984 | Antiproliferative activity against human K562 cells | 2012 | Journal of natural products, Oct-26, Volume: 75, Issue:10 | Elaiomycins D-F, antimicrobial and cytotoxic azoxides from Streptomyces sp. strain HKI0708. |
| AID691987 | Antibacterial activity against Staphylococcus aureus 511 B3 assessed as zone of inhibition at 50 ug/disc after 24 hrs by agar diffusion assay | 2012 | Journal of natural products, Oct-26, Volume: 75, Issue:10 | Elaiomycins D-F, antimicrobial and cytotoxic azoxides from Streptomyces sp. strain HKI0708. |
| AID691978 | Cytotoxicity against human PAXF 1657L cells by propidium iodide-based fluorescence assay | 2012 | Journal of natural products, Oct-26, Volume: 75, Issue:10 | Elaiomycins D-F, antimicrobial and cytotoxic azoxides from Streptomyces sp. strain HKI0708. |
| AID691988 | Antibacterial activity against Escherichia coli 458 B4 assessed as zone of inhibition at 50 ug/disc after 24 hrs by agar diffusion assay | 2012 | Journal of natural products, Oct-26, Volume: 75, Issue:10 | Elaiomycins D-F, antimicrobial and cytotoxic azoxides from Streptomyces sp. strain HKI0708. |
| AID691838 | Cytotoxicity against human GXF251L cells by propidium iodide-based fluorescence assay | 2012 | Journal of natural products, Oct-26, Volume: 75, Issue:10 | Elaiomycins D-F, antimicrobial and cytotoxic azoxides from Streptomyces sp. strain HKI0708. |
| AID691983 | Antiproliferative activity against HUVEC | 2012 | Journal of natural products, Oct-26, Volume: 75, Issue:10 | Elaiomycins D-F, antimicrobial and cytotoxic azoxides from Streptomyces sp. strain HKI0708. |
| AID691994 | Antifungal activity against Sporidiobolus salmonicolor 549 H4 assessed as zone of inhibition at 50 ug/disc after 24 hrs by agar diffusion assay | 2012 | Journal of natural products, Oct-26, Volume: 75, Issue:10 | Elaiomycins D-F, antimicrobial and cytotoxic azoxides from Streptomyces sp. strain HKI0708. |
| AID691974 | Cytotoxicity against human LXFL 529L cells by propidium iodide-based fluorescence assay | 2012 | Journal of natural products, Oct-26, Volume: 75, Issue:10 | Elaiomycins D-F, antimicrobial and cytotoxic azoxides from Streptomyces sp. strain HKI0708. |
| AID691989 | Antibacterial activity against Pseudomonas aeruginosa SG 137 B7 assessed as zone of inhibition at 50 ug/disc after 24 hrs by agar diffusion assay | 2012 | Journal of natural products, Oct-26, Volume: 75, Issue:10 | Elaiomycins D-F, antimicrobial and cytotoxic azoxides from Streptomyces sp. strain HKI0708. |
| AID691985 | Cytotoxicity against human HeLa cells | 2012 | Journal of natural products, Oct-26, Volume: 75, Issue:10 | Elaiomycins D-F, antimicrobial and cytotoxic azoxides from Streptomyces sp. strain HKI0708. |
| AID691982 | Cytotoxicity against human UXF 1138L cells by propidium iodide-based fluorescence assay | 2012 | Journal of natural products, Oct-26, Volume: 75, Issue:10 | Elaiomycins D-F, antimicrobial and cytotoxic azoxides from Streptomyces sp. strain HKI0708. |
| AID691836 | Antifungal activity against Aspergillus niger DSM 737 assessed as zone of inhibition at 50 ug/disc after 24 hrs by agar diffusion assay | 2012 | Journal of natural products, Oct-26, Volume: 75, Issue:10 | Elaiomycins D-F, antimicrobial and cytotoxic azoxides from Streptomyces sp. strain HKI0708. |
| AID691991 | Antibacterial activity against methicillin-resistant Staphylococcus aureus 134/93 R9 assessed as zone of inhibition at 50 ug/disc after 24 hrs by agar diffusion assay | 2012 | Journal of natural products, Oct-26, Volume: 75, Issue:10 | Elaiomycins D-F, antimicrobial and cytotoxic azoxides from Streptomyces sp. strain HKI0708. |
| AID691976 | Cytotoxicity against human MEXF 462NL cells by propidium iodide-based fluorescence assay | 2012 | Journal of natural products, Oct-26, Volume: 75, Issue:10 | Elaiomycins D-F, antimicrobial and cytotoxic azoxides from Streptomyces sp. strain HKI0708. |
| AID691839 | Cytotoxicity against human LXFA 629L cells by propidium iodide-based fluorescence assay | 2012 | Journal of natural products, Oct-26, Volume: 75, Issue:10 | Elaiomycins D-F, antimicrobial and cytotoxic azoxides from Streptomyces sp. strain HKI0708. |
| AID691980 | Cytotoxicity against human PXF 1752L cells by propidium iodide-based fluorescence assay | 2012 | Journal of natural products, Oct-26, Volume: 75, Issue:10 | Elaiomycins D-F, antimicrobial and cytotoxic azoxides from Streptomyces sp. strain HKI0708. |
| AID691993 | Antibacterial activity against Mycobacterium vaccae 10670 M4 assessed as zone of inhibition at 50 ug/disc after 24 hrs by agar diffusion assay | 2012 | Journal of natural products, Oct-26, Volume: 75, Issue:10 | Elaiomycins D-F, antimicrobial and cytotoxic azoxides from Streptomyces sp. strain HKI0708. |
| AID691995 | Antifungal activity against Candida albicans H8 assessed as zone of inhibition at 50 ug/disc after 24 hrs by agar diffusion assay | 2012 | Journal of natural products, Oct-26, Volume: 75, Issue:10 | Elaiomycins D-F, antimicrobial and cytotoxic azoxides from Streptomyces sp. strain HKI0708. |
| AID691992 | Antibacterial activity against vancomycin-resistant Enterococcus faecalis 1528 R10 assessed as zone of inhibition at 50 ug/disc after 24 hrs by agar diffusion assay | 2012 | Journal of natural products, Oct-26, Volume: 75, Issue:10 | Elaiomycins D-F, antimicrobial and cytotoxic azoxides from Streptomyces sp. strain HKI0708. |
| AID691986 | Antibacterial activity against Bacillus subtilis 6633 B1 assessed as zone of inhibition at 50 ug/disc after 24 hrs by agar diffusion assay | 2012 | Journal of natural products, Oct-26, Volume: 75, Issue:10 | Elaiomycins D-F, antimicrobial and cytotoxic azoxides from Streptomyces sp. strain HKI0708. |
| AID691979 | Cytotoxicity against human PRXF 22Rv1 cells by propidium iodide-based fluorescence assay | 2012 | Journal of natural products, Oct-26, Volume: 75, Issue:10 | Elaiomycins D-F, antimicrobial and cytotoxic azoxides from Streptomyces sp. strain HKI0708. |
| AID691835 | Antifungal activity against amphotericin-resistant Aspergillus terreus DSM 826 assessed as zone of inhibition at 50 ug/disc after 24 hrs by agar diffusion assay | 2012 | Journal of natural products, Oct-26, Volume: 75, Issue:10 | Elaiomycins D-F, antimicrobial and cytotoxic azoxides from Streptomyces sp. strain HKI0708. |
| AID691837 | Cytotoxicity against human CXF HT29 cells by propidium iodide-based fluorescence assay | 2012 | Journal of natural products, Oct-26, Volume: 75, Issue:10 | Elaiomycins D-F, antimicrobial and cytotoxic azoxides from Streptomyces sp. strain HKI0708. |
| AID691990 | Antibacterial activity against Pseudomonas aeruginosa K 799/61 B9 assessed as zone of inhibition at 50 ug/disc after 24 hrs by agar diffusion assay | 2012 | Journal of natural products, Oct-26, Volume: 75, Issue:10 | Elaiomycins D-F, antimicrobial and cytotoxic azoxides from Streptomyces sp. strain HKI0708. |
| AID691977 | Cytotoxicity against human OVXF 899L cells by propidium iodide-based fluorescence assay | 2012 | Journal of natural products, Oct-26, Volume: 75, Issue:10 | Elaiomycins D-F, antimicrobial and cytotoxic azoxides from Streptomyces sp. strain HKI0708. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
Research
Studies (8)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 6 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 17.31
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (17.31) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 8 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||