| Assay ID | Title | Year | Journal | Article |
|---|
| AID87725 | In vitro anticellular activity expressed as inhibitory concentration for the growth of HeLa S3 cells for a period of 72 hour | 1997 | Journal of medicinal chemistry, Mar-14, Volume: 40, Issue:6
| Synthesis and antitumor activity of duocarmycin derivatives: A-ring pyrrole compounds bearing cinnamoyl groups. |
| AID134326 | Hematotoxicity determined as number of peripheral platelets of normal mice on day 7 (percent of control) | 1999 | Journal of medicinal chemistry, Jul-29, Volume: 42, Issue:15
| Synthesis and antitumor activity of duocarmycin derivatives: modification of segment-A of A-ring pyrrole compounds. |
| AID87747 | In vitro inhibition of HeLa S3 cell growth by 50% after 1 hr. | 1999 | Journal of medicinal chemistry, Jul-29, Volume: 42, Issue:15
| Synthesis and antitumor activity of duocarmycin derivatives: modification of segment-A of A-ring pyrrole compounds. |
| AID116118 | In vivo antitumor activity (0.125 mg/Kg) is the measure of increase in life span of mice bearing P388 murine leukemia cells | 1999 | Journal of medicinal chemistry, Apr-22, Volume: 42, Issue:8
| Novel cyclopropapyrroloindole derivative (AT-3510) bearing methoxycarbonyl and trifluoromethyl groups. |
| AID87726 | In vitro anticellular activity expressed as inhibitory concentration for the growth of human uterine cervix carcinoma HeLa S3 cells for a period of 1 hour | 1997 | Journal of medicinal chemistry, Mar-14, Volume: 40, Issue:6
| Synthesis and antitumor activity of duocarmycin derivatives: A-ring pyrrole compounds bearing cinnamoyl groups. |
| AID134791 | lethal toxicity of compound was determined by calculating mortality in 10 ddY mice at the dose of 0.20 mg/kg | 1999 | Journal of medicinal chemistry, Jul-29, Volume: 42, Issue:15
| Synthesis and antitumor activity of duocarmycin derivatives: modification of segment-A of A-ring pyrrole compounds. |
| AID134794 | lethal toxicity of compound was determined by calculating mortality in 10 ddY mice at the dose of 0.29 mg/kg | 1999 | Journal of medicinal chemistry, Jul-29, Volume: 42, Issue:15
| Synthesis and antitumor activity of duocarmycin derivatives: modification of segment-A of A-ring pyrrole compounds. |
| AID122153 | In vivo antitumor activity (0.5 mg/Kg) is the measure of tumor growth inhibition in mice bearing S180 murine sarcoma cells | 1999 | Journal of medicinal chemistry, Apr-22, Volume: 42, Issue:8
| Novel cyclopropapyrroloindole derivative (AT-3510) bearing methoxycarbonyl and trifluoromethyl groups. |
| AID134797 | lethal toxicity of compound was determined by calculating mortality in 10 ddY mice at the dose of 0.42 mg/kg | 1999 | Journal of medicinal chemistry, Jul-29, Volume: 42, Issue:15
| Synthesis and antitumor activity of duocarmycin derivatives: modification of segment-A of A-ring pyrrole compounds. |
| AID134796 | lethal toxicity of compound was determined by calculating mortality in 10 ddY mice at the dose of 0.35 mg/kg | 1999 | Journal of medicinal chemistry, Jul-29, Volume: 42, Issue:15
| Synthesis and antitumor activity of duocarmycin derivatives: modification of segment-A of A-ring pyrrole compounds. |
| AID150651 | In vitro concentration required to inhibit the growth of P338 murine leukemia cells by 50% | 1999 | Journal of medicinal chemistry, Apr-22, Volume: 42, Issue:8
| Novel cyclopropapyrroloindole derivative (AT-3510) bearing methoxycarbonyl and trifluoromethyl groups. |
| AID134790 | lethal toxicity of compound was determined by calculating mortality in 10 ddY mice at the dose of 0.17 mg/kg | 1999 | Journal of medicinal chemistry, Jul-29, Volume: 42, Issue:15
| Synthesis and antitumor activity of duocarmycin derivatives: modification of segment-A of A-ring pyrrole compounds. |
| AID140832 | Hematotoxicity determined as number of white blood cells of tumor-bearing mice on day 4 (percent of control). | 1999 | Journal of medicinal chemistry, Jul-29, Volume: 42, Issue:15
| Synthesis and antitumor activity of duocarmycin derivatives: modification of segment-A of A-ring pyrrole compounds. |
| AID87748 | In vitro inhibition HeLa S3 cell growth by 50% after 72 hr. | 1999 | Journal of medicinal chemistry, Jul-29, Volume: 42, Issue:15
| Synthesis and antitumor activity of duocarmycin derivatives: modification of segment-A of A-ring pyrrole compounds. |
| AID137065 | In vivo antitumor activity expressed as T/C in mice implanted subcutaneously (sc) with sarcoma180 tumor cells, and dose 0.25(mg/kg) administered intravenously | 1999 | Journal of medicinal chemistry, Jul-29, Volume: 42, Issue:15
| Synthesis and antitumor activity of duocarmycin derivatives: modification of segment-A of A-ring pyrrole compounds. |
| AID134798 | lethal toxicity of compound was determined by calculating mortality in 10 ddY mice at the dose of 0.50 mg/kg | 1999 | Journal of medicinal chemistry, Jul-29, Volume: 42, Issue:15
| Synthesis and antitumor activity of duocarmycin derivatives: modification of segment-A of A-ring pyrrole compounds. |
| AID134793 | lethal toxicity of compound was determined by calculating mortality in 10 ddY mice at the dose of 0.24 mg/kg | 1999 | Journal of medicinal chemistry, Jul-29, Volume: 42, Issue:15
| Synthesis and antitumor activity of duocarmycin derivatives: modification of segment-A of A-ring pyrrole compounds. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |