Page last updated: 2024-12-07

dodecyltriphenylphosphonium

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Dodecyltriphenylphosphonium is a quaternary ammonium salt that has been studied for its potential applications in various fields, including catalysis, materials science, and medicine. Its synthesis typically involves the reaction of triphenylphosphine with dodecyl bromide. Dodecyltriphenylphosphonium exhibits a unique combination of properties, including its hydrophobic dodecyl tail and hydrophilic triphenylphosphonium head group, which make it suitable for various applications. For example, it has been used as a catalyst in organic reactions, as a surfactant in the synthesis of nanomaterials, and as a potential drug delivery agent. The compound's importance lies in its ability to interact with both hydrophobic and hydrophilic environments, facilitating the formation of new materials and enhancing the efficiency of various chemical processes. Its applications are being actively investigated in research, and it holds promising potential for future advancements in diverse fields.'

dodecyltriphenylphosphonium: RN given refers to bromide; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

dodecyl(triphenyl)phosphonium : A polyatomic cation consisting of a dodecyl group and three phenyl groups attached to a central phosphonium. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID84956
CHEMBL ID3306671
CHEBI ID82636
SCHEMBL ID427955
MeSH IDM0041214

Synonyms (11)

Synonym
dodecyltriphenylphosphonium
dodecyl(triphenyl)phosphanium
SCHEMBL427955
CHEBI:82636 ,
dodecyl(triphenyl)phosphonium
c(12)tpp(+)
c12tpp(+)
CHEMBL3306671
DTXSID70904622
17895-72-6
Q27156152
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (3)

ClassDescription
polyatomic cationA cation consisting of more than one atom.
phosphorus molecular entity
heteroorganic entityA heteroorganic entity is an organic molecular entity in which carbon atoms or organic groups are bonded directly to one or more heteroatoms.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (2)

Assay IDTitleYearJournalArticle
AID1512652Antiobesity activity in high fat diet-induced obese C57BL/6 mouse assessed as reduction in fat mass at 50 umol/kg/day for 16 days relative to control2018Journal of medicinal chemistry, 06-14, Volume: 61, Issue:11
Small Molecule Mitochondrial Uncouplers and Their Therapeutic Potential.
AID1512651Antiobesity activity in high fat diet-induced obese C57BL/6 mouse assessed as reduction in body weight at 50 umol/kg/day for 16 days relative to control2018Journal of medicinal chemistry, 06-14, Volume: 61, Issue:11
Small Molecule Mitochondrial Uncouplers and Their Therapeutic Potential.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (12)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (8.33)18.2507
2000's0 (0.00)29.6817
2010's10 (83.33)24.3611
2020's1 (8.33)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.76

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.76 (24.57)
Research Supply Index2.56 (2.92)
Research Growth Index4.32 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.76)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (8.33%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other11 (91.67%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]