Compounds > dioctadecylamine
Page last updated: 2024-12-06

dioctadecylamine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Dioctadecylamine (DODA) is a long-chain aliphatic amine with a high molecular weight. It is a white, waxy solid that is insoluble in water but soluble in organic solvents. DODA is often used as a surfactant, emulsifier, and corrosion inhibitor. It is also used in the synthesis of other compounds, such as quaternary ammonium salts. DODA is a common component of cationic surfactants, which are used in a wide variety of applications, including detergents, cosmetics, and pharmaceuticals. The hydrophobic nature of DODA makes it effective at lowering the surface tension of water and forming stable emulsions. Its amphiphilic properties allow it to interact with both polar and nonpolar molecules, making it useful for a variety of applications. DODA is studied for its properties as a surfactant and its potential uses in different industries. Research into its synthesis and applications continues to expand.'

Cross-References

ID SourceID
PubMed CID66989
SCHEMBL ID238963
MeSH IDM0252269

Synonyms (31)

Synonym
dioctadecylamine
n-octadecyloctadecan-1-amine
112-99-2
distearylamine
dioctadecylamine, >=99.0% (nt)
n-octadecyl-1-octadecanamine
A802714
einecs 204-020-2
569inv7sp8 ,
unii-569inv7sp8
1-octadecanamine, n-octadecyl-
FT-0631650
AKOS015915146
SCHEMBL238963
bis(octadecyl)amine
genamin sh 200
n,n-dioctadecylamine
di-n-octadecylamine
armeen 2-18
bis-octadecylamine
dioctadecyl amine
distearyl amine
DTXSID8059425
W-108629
HY-142981
Q27261391
doda, distearylamine
CS-0374628
F87450
doda
dioctadecylamine(doda)

Research Excerpts

Bioavailability

ExcerptReferenceRelevance
" A number of methods are used to reduce toxicity and improve the bioavailability of the fatty amine derivatives in these tests."( Improving ready biodegradability testing of fatty amine derivatives.
Galobardes, M; Gancet, C; Hirschen, M; Lemaire, P; Rosenblom, J; van Ginkel, CG, 2008)		0.35
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's4 (66.67)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 28.20

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index28.20 (24.57)
Research Supply Index2.20 (2.92)
Research Growth Index4.78 (4.65)
Search Engine Demand Index24.28 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (28.20)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other8 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
chlorine
chloride : A halide anion formed when chlorine picks up an electron to form an an anion.		2.0210halide anion;
monoatomic chlorine		cofactor;
Escherichia coli metabolite;
human metabolite
trimethylenediamine
trimethylenediamine: RN given refers to parent cpd; structure. trimethylenediamine : An alkane-alpha,omega-diamine comprising a propane skeleton with amino substituents at positions 1 and 3.		2.0410alkane-alpha,omega-diaminehuman metabolite;
mouse metabolite;
reagent
erythrosine
Fluoresceins: A family of spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one derivatives. These are used as dyes, as indicators for various metals, and as fluorescent labels in immunoassays.		2.0210
histidine
Histidine: An essential amino acid that is required for the production of HISTAMINE.. L-histidine : The L-enantiomer of the amino acid histidine.. histidine : An alpha-amino acid that is propanoic acid bearing an amino substituent at position 2 and a 1H-imidazol-4-yl group at position 3.		1.9810amino acid zwitterion;
histidine;
L-alpha-amino acid;
polar amino acid zwitterion;
proteinogenic amino acid		algal metabolite;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
nitrilotriacetic acid
Nitrilotriacetic Acid: A derivative of acetic acid, N(CH2COOH)3. It is a complexing (sequestering) agent that forms stable complexes with Zn2+. (From Miall's Dictionary of Chemistry, 5th ed.)		1.9810NTA;
tricarboxylic acid		carcinogenic agent;
nephrotoxic agent
1,2-dipalmitoyl-3-phosphatidylethanolamine
1,2-dipalmitoyl-3-phosphatidylethanolamine: RN given refers to parent cpd without isomeric designation		1.9810
1,2-distearoyllecithin
[no description available]		2.0210
6-carboxyfluorescein
6-carboxyfluorescein: originally sold as 6-carboxyfluorescein, but commercial product is a mixture of two isomers; correct name is 5(6)-carboxyfluorescein		2.0210monocarboxylic acid
valinomycin
Valinomycin: A cyclododecadepsipeptide ionophore antibiotic produced by Streptomyces fulvissimus and related to the enniatins. It is composed of 3 moles each of L-valine, D-alpha-hydroxyisovaleric acid, D-valine, and L-lactic acid linked alternately to form a 36-membered ring. (From Merck Index, 11th ed) Valinomycin is a potassium selective ionophore and is commonly used as a tool in biochemical studies.. valinomycin : A twelve-membered cyclodepsipeptide composed of three repeating D-alpha-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl units joined in sequence. An antibiotic found in several Streptomyces strains.		2.0510cyclodepsipeptide;
macrocycle		antimicrobial agent;
antiviral agent;
bacterial metabolite;
potassium ionophore
dimyristoylphosphatidylcholine
1,2-di-O-myristoyl-sn-glycero-3-phosphocholine : A 1,2-diacyl-sn-glycero-3-phosphocholine where the two phosphatidyl acyl groups are specified as tetradecanoyl (myristoyl).. dimyristoyl phosphatidylcholine : A phosphatidylcholine where the phosphatidyl acyl groups are specified as tetradecanoyl (myristoyl).		1.98101,2-diacyl-sn-glycero-3-phosphocholine;
phosphatidylcholine 28:0;
tetradecanoate ester		antigen;
mouse metabolite
phosphatidylcholines
Phosphatidylcholines: Derivatives of PHOSPHATIDIC ACIDS in which the phosphoric acid is bound in ester linkage to a CHOLINE moiety.		2.02101,2-diacyl-sn-glycero-3-phosphocholine
ConditionIndicatedRelationship StrengthStudiesTrials