Compounds > dioctadecylamidospermine
Page last updated: 2024-12-07

dioctadecylamidospermine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID131609
MeSH IDM0175737

Synonyms (8)

Synonym
dioctadecylamidospermine
2,5-bis(3-aminopropylamino)-n,n-dioctadecylpentanamide
133294-12-9
2,5-bis((3-aminopropyl)amino)-n,n-dioctadecylpentanamide
pentanamide, 2,5-bis(3-aminopropyl)amino)-n,n-dioctadecyl-
1-dos
DTXSID10928044
n~2~,n~5~-bis(3-aminopropyl)-n,n-dioctadecylornithinamide

Research Excerpts

Toxicity

ExcerptReferenceRelevance
" No serious or severe adverse events were detected."( Safety and immunogenicity of rAd26 and rAd5 vector-based heterologous prime-boost COVID-19 vaccine against SARS-CoV-2 in healthy adolescents: an open-label, non-randomized, multicenter, phase 1/2, dose-escalation study.
Borzakova, SN; Dolzhikova, IV; Dzharullaeva, AS; Erokhova, AS; Esmagambetov, IB; Gintsburg, AL; Gorev, VV; Grousova, DM; Gushchin, VA; Iliukhina, AA; Izhaeva, FM; Khadorich, EA; Kovyrshina, AV; Logunov, DY; Lubenets, NL; Naroditsky, BS; Nikitenko, NA; Osmanov, IM; Ozharovskaia, TA; Popova, O; Shcheblyakov, DV; Shelkov, AY; Tokarskaya, EA; Tukhvatulin, AI; Vlasova, AV; Zorkov, ID; Zrelkin, DI; Zubkova, OV, 2023)		0.91
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (8)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's1 (12.50)29.6817
2010's0 (0.00)24.3611
2020's6 (75.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.05

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.05 (24.57)
Research Supply Index2.30 (2.92)
Research Growth Index4.36 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.05)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (12.50%)5.53%
Reviews1 (12.50%)6.00%
Case Studies0 (0.00%)4.05%
Observational2 (25.00%)0.25%
Other4 (50.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
glycine
[no description available]		1.9710alpha-amino acid;
amino acid zwitterion;
proteinogenic amino acid;
serine family amino acid		EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor;
fundamental metabolite;
hepatoprotective agent;
micronutrient;
neurotransmitter;
NMDA receptor agonist;
nutraceutical
spermine
[no description available]		2.3920polyazaalkane;
tetramine		antioxidant;
fundamental metabolite;
immunosuppressive agent
chlorates
Chlorates: Inorganic salts of chloric acid that contain the ClO3- ion.		210chlorine oxoanion;
monovalent inorganic anion
dioctadecylamidoglycylspermine
dioctadecylamidoglycylspermine: a lipospermine used to coat DNA to facilitate gene transfer into mammalian primary endocrine cells; structure given in first source		1.9710
sodium chlorate
sodium chlorate : An inorganic sodium salt that has chlorate as the counter-ion. An oxidising agent, it is used for bleaching paper and as a herbicide. It is also used in the manufacture of dyes, explosives and matches.		210chlorate salt;
inorganic sodium salt		herbicide
msh, 4-nle-7-phe-alpha-
[no description available]		210polypeptidedermatologic drug
ConditionIndicatedRelationship StrengthStudiesTrials
2019 Novel Coronavirus Disease
[description not available]		06.1661
Anaphylactic Reaction
[description not available]		02.610
Anaphylaxis
An acute hypersensitivity reaction due to exposure to a previously encountered ANTIGEN. The reaction may include rapidly progressing URTICARIA, respiratory distress, vascular collapse, systemic SHOCK, and death.		02.610