Compounds > dimethylsilanediol
Page last updated: 2024-12-05

dimethylsilanediol

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID14014
CHEBI ID23816
MeSH IDM0368736

Synonyms (22)

Synonym
unii-dnz4kje28u
silanediol, 1,1-dimethyl-
einecs 213-915-7
dnz4kje28u ,
silanediol, dimethyl-
CHEBI:23816
dimethylsilanediol
(ch3)2si(oh)2
1066-42-8
si(oh)2me2
dihydroxy(dimethyl)silane
DTXSID2061434
dihydroxydimethylsilane
XCLIHDJZGPCUBT-UHFFFAOYSA-N
dimethylsilanediol #
31692-79-2
1,1-dimethylsilanediol
Q1225753
A934210
polydimethylsiloxane, hydroxy terminated, m.w. 4200
poly(dimethylsiloxane) hydroxy terminated
F71313

Research Excerpts

Overview

Dimethylsilanediol is a stable crystalline solid that was described in 1953.

ExcerptReferenceRelevance
"Dimethylsilanediol is a stable crystalline solid that was described in 1953. "( Hydrophobization of inorganic oxide surfaces using dimethylsilanediol.
Krumpfer, JW; Lin, Y; McCarthy, TJ; Wang, L; Watkins, JJ, 2013)		2.08

Toxicity

ExcerptReferenceRelevance
" The Cosmetic Ingredient Review (CIR) Expert Panel reviewed relevant data and concluded that these ingredients are safe in the present practices of use and concentration described in this safety assessment."( Safety Assessment of Dimethiconol and Its Esters and Reaction Products as Used in Cosmetics.
Andersen, FA; Belsito, DV; Bergfeld, WF; Heldreth, B; Hill, RA; Johnson, W; Klaassen, CD; Liebler, DC; Marks, JG; Shank, RC; Slaga, TJ; Snyder, PW, )		0.13

Bioavailability

ExcerptReferenceRelevance
"Removing volatile methyl siloxanes (VMSs) from biogas remains a longstanding challenge in the field of biological process due to their low bioavailability and biodegradation."( Siloxanes removal from biogas by a lab-scale biotrickling filter inoculated with Pseudomonas aeruginosa S240.
Li, Y; Xu, J; Zhang, W, 2014)		0.4
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
organosilanediol
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (28.57)29.6817
2010's5 (71.43)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 37.37

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index37.37 (24.57)
Research Supply Index2.20 (2.92)
Research Growth Index5.21 (4.65)
Search Engine Demand Index45.55 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (37.37)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (12.50%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (87.50%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
ammonium hydroxide
azane : Saturated acyclic nitrogen hydrides having the general formula NnHn+2.		2.0810azane;
gas molecular entity;
mononuclear parent hydride		EC 3.5.1.4 (amidase) inhibitor;
metabolite;
mouse metabolite;
neurotoxin;
NMR chemical shift reference compound;
nucleophilic reagent;
refrigerant
methanol
Methanol: A colorless, flammable liquid used in the manufacture of FORMALDEHYDE and ACETIC ACID, in chemical synthesis, antifreeze, and as a solvent. Ingestion of methanol is toxic and may cause blindness.. primary alcohol : A primary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.. methanol : The primary alcohol that is the simplest aliphatic alcohol, comprising a methyl and an alcohol group.		2.110alkyl alcohol;
one-carbon compound;
primary alcohol;
volatile organic compound		amphiprotic solvent;
Escherichia coli metabolite;
fuel;
human metabolite;
mouse metabolite;
Mycoplasma genitalium metabolite
nickel
Nickel: A trace element with the atomic symbol Ni, atomic number 28, and atomic weight 58.69. It is a cofactor of the enzyme UREASE.. nickel ion : A nickel atom having a net electric charge.. nickel atom : Chemical element (nickel group element atom) with atomic number 28.		2.0810metal allergen;
nickel group element atom		epitope;
micronutrient
octamethylcyclotetrasiloxane
octamethylcyclotetrasiloxane: structure. octamethylcyclotetrasiloxane : A cyclosiloxane that is the octamethyl derivative of cyclotetrasiloxane.		2.110cyclosiloxane;
organosilicon compound
silanediol
silanediol: structure in first source		2.0810silicon hydroxide
ConditionIndicatedRelationship StrengthStudiesTrials