digitoxigenin monodigitoxoside: RN given refers to (ribo-3beta,5beta)-isomer [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 11961867 |
| CHEMBL ID | 1651624 |
| MeSH ID | M0108713 |
| Synonym |
|---|
| evatromonoside |
| digitoxigenin monodigitoxoside |
| beta-d-digitoxose |
| CHEMBL1651624 |
| 3-[(3s,5r,8r,9s,10s,13r,14s,17r)-3-[(2r,4s,5s,6r)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-14-hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2h-furan-5-one |
| 3-[(3r,5r,10s,13r,14s,17r)-3-[(2r,5s)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-14-hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2h-furan-5-one |
| d-ribo-hexopyranoside, digitoxigenin-3 2,6-dideoxy-, .beta.- |
| 4-((1r,3as,3br,5ar,7s,9as,9bs,11ar)-7-(((2r,4s,5s,6r)-4,5-dihydroxy-6-methyloxan-2-yl)oxy)-3a-hydroxy-9a,11a-dimethyl-hexadecahydro-1h-cyclopenta(a)phenanthren-1-yl)-2,5-dihydrofuran-2-one |
| card-20(22)-enolide, 3-((2,6-dideoxy-.beta.-d-ribo-hexopyranosyl)oxy)-14-hydroxy-, (3.beta.,5.beta.)- |
| (3.beta.,5.beta.)-3-((2,6-dideoxy-.beta.-d-ribo-hexopyranosyl)oxy)-14-hydroxycard-20(22)-enolide |
| digitoxigenin mono-.beta.-d-digitoxoside |
| Excerpt | Reference | Relevance |
|---|---|---|
| " However, the mean bioavailability of unchanged bisdigitoxoside was only 56." | ( Bioavailability of the bis- and monodigitoxosides of digitoxigenin. Fenster, PE; Graves, PE; MacFarland, RT; Marcus, FI; Perrier, D, 1985) | 0.27 |
| Protein | Taxonomy | Measurement | Average | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| Sodium/potassium-transporting ATPase subunit alpha-1 | Homo sapiens (human) | IC50 (µMol) | 0.0070 | 0.0048 | 0.7807 | 6.0000 | AID146845 |
| Sodium/potassium-transporting ATPase subunit beta-1 | Homo sapiens (human) | IC50 (µMol) | 0.0070 | 0.0048 | 0.8134 | 6.0000 | AID146845 |
| Sodium/potassium-transporting ATPase subunit alpha-3 | Homo sapiens (human) | IC50 (µMol) | 0.0070 | 0.0048 | 0.8134 | 6.0000 | AID146845 |
| Sodium/potassium-transporting ATPase subunit beta-2 | Homo sapiens (human) | IC50 (µMol) | 0.0070 | 0.0048 | 0.8134 | 6.0000 | AID146845 |
| Sodium/potassium-transporting ATPase subunit alpha-2 | Homo sapiens (human) | IC50 (µMol) | 0.0070 | 0.0048 | 0.8134 | 6.0000 | AID146845 |
| Sodium/potassium-transporting ATPase subunit beta-3 | Homo sapiens (human) | IC50 (µMol) | 0.0070 | 0.0048 | 0.8134 | 6.0000 | AID146845 |
| Sodium/potassium-transporting ATPase subunit gamma | Homo sapiens (human) | IC50 (µMol) | 0.0070 | 0.0048 | 0.8134 | 6.0000 | AID146845 |
| Sodium/potassium-transporting ATPase subunit alpha-4 | Homo sapiens (human) | IC50 (µMol) | 0.0070 | 0.0048 | 0.8134 | 6.0000 | AID146845 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 11 (68.75) | 18.7374 |
| 1990's | 2 (12.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (18.75) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 22 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||