Compounds > dichlorophenyl-bis-triazolylpropanol
Page last updated: 2024-12-07

dichlorophenyl-bis-triazolylpropanol

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

dichlorophenyl-bis-triazolylpropanol: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID133777
CHEMBL ID1977368
CHEBI ID9848
SCHEMBL ID8057057
MeSH IDM0160346

Synonyms (18)

Synonym
dichlorophenyl-bis-triazolylpropanol
1h-1,2,4-triazole-1-ethanol, alpha-(2,4-dichlorophenyl)-alpha-(1h-1,2,4-triazol-1-ylmethyl)-
uk 47265
alpha-(2,4-dichlorophenyl)-alpha-(triazol-1-ylmethyl)-as-triazoleethanol
2-(2,4-dichlorophenyl)-1,3-bis(1h-1,2,4-triazol-1-yl)propan-2-ol
2-(2,4-dichlorophenyl)-1,3-di(1h-1,2,4-triazol-1-yl)-2-propanol
2-(2,4-dichlorophenyl)-1,3-bis(1,2,4-triazol-1-yl)propan-2-ol
NCI60_018173
nsc-651919
nsc651919
uk-47265
81886-52-4
AC1Q3MZH ,
DTXSID90231447
CHEBI:9848 ,
SCHEMBL8057057
CHEMBL1977368
Q27108501
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
amineA compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (10)

Assay IDTitleYearJournalArticle
AID1168327Binding affinity to human serum albumin at 298 K by modified Stern-Volmer method2014Bioorganic & medicinal chemistry letters, Nov-01, Volume: 24, Issue:21
Study the interactions between human serum albumin and two antifungal drugs: fluconazole and its analogue DTP.
AID1168330Binding affinity to human serum albumin at 298 K by Scatchard method2014Bioorganic & medicinal chemistry letters, Nov-01, Volume: 24, Issue:21
Study the interactions between human serum albumin and two antifungal drugs: fluconazole and its analogue DTP.
AID1168325Binding affinity to human serum albumin assessed as formation of non-fluorescent compound-protein complex at 302 K at pH 7.4 by fluorescence quenching method2014Bioorganic & medicinal chemistry letters, Nov-01, Volume: 24, Issue:21
Study the interactions between human serum albumin and two antifungal drugs: fluconazole and its analogue DTP.
AID1168331Binding affinity to human serum albumin at 302 K by Scatchard method2014Bioorganic & medicinal chemistry letters, Nov-01, Volume: 24, Issue:21
Study the interactions between human serum albumin and two antifungal drugs: fluconazole and its analogue DTP.
AID1168332Binding affinity to human serum albumin at 310 K by Scatchard method2014Bioorganic & medicinal chemistry letters, Nov-01, Volume: 24, Issue:21
Study the interactions between human serum albumin and two antifungal drugs: fluconazole and its analogue DTP.
AID1168324Binding affinity to human serum albumin assessed as formation of non-fluorescent compound-protein complex at 298 K at pH 7.4 by fluorescence quenching method2014Bioorganic & medicinal chemistry letters, Nov-01, Volume: 24, Issue:21
Study the interactions between human serum albumin and two antifungal drugs: fluconazole and its analogue DTP.
AID1168329Binding affinity to human serum albumin at 310 K by modified Stern-Volmer method2014Bioorganic & medicinal chemistry letters, Nov-01, Volume: 24, Issue:21
Study the interactions between human serum albumin and two antifungal drugs: fluconazole and its analogue DTP.
AID1168328Binding affinity to human serum albumin at 302 K by modified Stern-Volmer method2014Bioorganic & medicinal chemistry letters, Nov-01, Volume: 24, Issue:21
Study the interactions between human serum albumin and two antifungal drugs: fluconazole and its analogue DTP.
AID1168323Binding affinity to human serum albumin at 0.4 to 5.6 x 10' -5 M by UV-Vis spectroscopy2014Bioorganic & medicinal chemistry letters, Nov-01, Volume: 24, Issue:21
Study the interactions between human serum albumin and two antifungal drugs: fluconazole and its analogue DTP.
AID1168326Binding affinity to human serum albumin assessed as formation of non-fluorescent compound-protein complex at 310 K at pH 7.4 by fluorescence quenching method2014Bioorganic & medicinal chemistry letters, Nov-01, Volume: 24, Issue:21
Study the interactions between human serum albumin and two antifungal drugs: fluconazole and its analogue DTP.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (4)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (25.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.72

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.72 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.51 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.72)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
fluconazole
Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.. fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.		2.6930conazole antifungal drug;
difluorobenzene;
tertiary alcohol;
triazole antifungal drug		environmental contaminant;
P450 inhibitor;
xenobiotic
ketoconazole
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.		1.9810dichlorobenzene;
dioxolane;
ether;
imidazoles;
N-acylpiperazine;
N-arylpiperazine
triazoles
Triazoles: Heterocyclic compounds containing a five-membered ring with two carbon atoms and three nitrogen atoms with the molecular formula C2H3N3.. triazoles : An azole in which the five-membered heterocyclic aromatic skeleton contains three N atoms and two C atoms.		2.91401,2,3-triazole
ConditionIndicatedRelationship StrengthStudiesTrials