Page last updated: 2024-12-06

dichloroacetylene

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID24227
CHEBI ID4503
MeSH IDM0043855

Synonyms (20)

Synonym
ethyne, dichloro-
acetylene, dichloro-
dichloroethyne
hsdb 7200
ccris 5411
dichloroacetylene [forbidden]
7572-29-4
dichloroacetylene
1,2-dichloroethyne
1,2-dichloro-ethyne
95i833jv4s ,
unii-95i833jv4s
dichloroacetylene [hsdb]
dichloroacetylene [iarc]
CHEBI:4503
clc.$.ccl
1,2-dichloroacetylene #
c2cl2
DTXSID7020429
Q20963653

Research Excerpts

Overview

Dichloroacetylene (DCA) is a highly reactive compound that decomposes rapidly in contact with air. It is a potent nephrotoxin and nephrocarcinogen in rodents.

ExcerptReferenceRelevance
"Dichloroacetylene (DCA) is a highly reactive compound that decomposes rapidly in contact with air into a series of chlorinated aliphatic hydrocarbons (e.g., phosgene, trichloroacetyl chloride, trichloroacryloyl chloride and hexachlorobutadiene). "( Mutagenicity of dichloroacetylene and its degradation products trichloroacetyl chloride, trichloroacryloyl chloride and hexachlorobutadiene.
Henschler, D; Neudecker, T; Reichert, D; Spengler, U, 1983
)
2.05
"Dichloroacetylene (DCA) is a by-product of the synthesis of certain chlorinated, aliphatic hydrocarbons (e.g., vinylidene chloride). "( Carcinogenicity of dichloroacetylene: an inhalation study.
Henschler, D; Reichert, D; Romen, W; Spengler, U, 1984
)
2.04
"Dichloroacetylene (DCA) is a potent nephrotoxin and nephrocarcinogen in rodents. "( Metabolism of the nephrotoxin dichloroacetylene by glutathione conjugation.
Dekant, W; Henschler, D; Kanhai, W,
)
1.86
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
organochlorine compoundAn organochlorine compound is a compound containing at least one carbon-chlorine bond.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (17)

TimeframeStudies, This Drug (%)All Drugs %
pre-19907 (41.18)18.7374
1990's6 (35.29)18.2507
2000's3 (17.65)29.6817
2010's1 (5.88)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 26.97

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index26.97 (24.57)
Research Supply Index3.04 (2.92)
Research Growth Index4.22 (4.65)
Search Engine Demand Index31.58 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (26.97)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (5.00%)6.00%
Case Studies1 (5.00%)4.05%
Observational0 (0.00%)0.25%
Other18 (90.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]