Page last updated: 2024-12-06
dichloroacetylene
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Cross-References
ID Source | ID |
---|---|
PubMed CID | 24227 |
CHEBI ID | 4503 |
MeSH ID | M0043855 |
Synonyms (20)
Synonym |
---|
ethyne, dichloro- |
acetylene, dichloro- |
dichloroethyne |
hsdb 7200 |
ccris 5411 |
dichloroacetylene [forbidden] |
7572-29-4 |
dichloroacetylene |
1,2-dichloroethyne |
1,2-dichloro-ethyne |
95i833jv4s , |
unii-95i833jv4s |
dichloroacetylene [hsdb] |
dichloroacetylene [iarc] |
CHEBI:4503 |
clc.$.ccl |
1,2-dichloroacetylene # |
c2cl2 |
DTXSID7020429 |
Q20963653 |
Research Excerpts
Overview
Dichloroacetylene (DCA) is a highly reactive compound that decomposes rapidly in contact with air. It is a potent nephrotoxin and nephrocarcinogen in rodents.
Excerpt | Reference | Relevance |
---|---|---|
"Dichloroacetylene (DCA) is a highly reactive compound that decomposes rapidly in contact with air into a series of chlorinated aliphatic hydrocarbons (e.g., phosgene, trichloroacetyl chloride, trichloroacryloyl chloride and hexachlorobutadiene). " | ( Mutagenicity of dichloroacetylene and its degradation products trichloroacetyl chloride, trichloroacryloyl chloride and hexachlorobutadiene. Henschler, D; Neudecker, T; Reichert, D; Spengler, U, 1983) | 2.05 |
"Dichloroacetylene (DCA) is a by-product of the synthesis of certain chlorinated, aliphatic hydrocarbons (e.g., vinylidene chloride). " | ( Carcinogenicity of dichloroacetylene: an inhalation study. Henschler, D; Reichert, D; Romen, W; Spengler, U, 1984) | 2.04 |
"Dichloroacetylene (DCA) is a potent nephrotoxin and nephrocarcinogen in rodents. " | ( Metabolism of the nephrotoxin dichloroacetylene by glutathione conjugation. Dekant, W; Henschler, D; Kanhai, W, ) | 1.86 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Drug Classes (1)
Class | Description |
---|---|
organochlorine compound | An organochlorine compound is a compound containing at least one carbon-chlorine bond. |
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Research
Studies (17)
Timeframe | Studies, This Drug (%) | All Drugs % |
---|---|---|
pre-1990 | 7 (41.18) | 18.7374 |
1990's | 6 (35.29) | 18.2507 |
2000's | 3 (17.65) | 29.6817 |
2010's | 1 (5.88) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 26.97
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (26.97) All Compounds (24.57) |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
---|---|---|
Trials | 0 (0.00%) | 5.53% |
Reviews | 1 (5.00%) | 6.00% |
Case Studies | 1 (5.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 18 (90.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |