Page last updated: 2024-12-05
dibutyl phenylphosphate
Dibutyl phenylphosphate (DBPP) is an organophosphate compound with potential applications in various fields. It has been studied for its use as a plasticizer, a flame retardant, and a component in hydraulic fluids. DBPP can be synthesized through the reaction of phenol with dibutyl phosphate. Research on DBPP focuses on understanding its properties, including its flammability, viscosity, and compatibility with other materials. Furthermore, studies have explored its environmental impact and potential toxicity. The importance of DBPP lies in its versatility and potential for various applications. However, its widespread use requires further research and evaluation to ensure its safety and minimize any potential environmental hazards.'
Cross-References
| ID Source | ID |
|---|
| PubMed CID | 17312 |
| CHEMBL ID | 4094240 |
| SCHEMBL ID | 124571 |
| MeSH ID | M0085484 |
Synonyms (25)
| Synonym |
|---|
| dibutyl phenyl phosphate |
| phosphoric acid, dibutyl phenyl ester |
| 2528-36-1 |
| hsdb 2604 |
| brn 2140519 |
| ccris 4604 |
| einecs 219-772-7 |
| di(n-butyl) phenyl phosphate |
| butyl phenyl phosphate ((buo)2(pho)po) |
| dibutyl phenylphosphate |
| lxx4uw7zyd , |
| 4-06-00-00710 (beilstein handbook reference) |
| unii-lxx4uw7zyd |
| dibutylphenylphosphate |
| phosphoric acid,dibutyl phenyl ester |
| dibutyl phenyl phosphate [hsdb] |
| SCHEMBL124571 |
| YICSVBJRVMLQNS-UHFFFAOYSA-N |
| bdbm50251511 |
| DTXSID50873428 |
| CHEMBL4094240 , |
| Q27283246 |
| CS-0246393 |
| EN300-323300 |
| Z2740773338 |
Research Excerpts
Toxicity
| Excerpt | Reference | Relevance |
|---|
| " The acute oral LD50 of TBP and DBPP were estimated to be 1,863 and 1,500 mg/kg, respectively, and the dose equal to the LD50 was used as a test dose." | ( Assessment of the delayed neurotoxicity of tributyl phosphate, tributoxyethyl phosphate, and dibutylphenyl phosphate.
Abou-Donia, MB; Carrington, CD; Farr, C; Johannsen, F; Lapadula, DM; Nair, RS; Othman, M, ) | 0.13 |
| " Although increases in liver, kidney, and adrenal weights were observed in certain animals in the 1600-ppm high-dose group, the administration of Phosflex 51B did not result in significant treatment-related adverse effects at dietary dose levels of 100 and 400 ppm." | ( A subchronic toxicity study of Phosflex 51B in Sprague-Dawley rats.
Brandwene, D; Clous, W; Freudenthal, RI, ) | 0.13 |
Protein Targets (1)
Inhibition Measurements
| Protein | Taxonomy | Measurement | Average | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|
| Cholinesterase | Equus caballus (horse) | Ki | 45.0000 | 0.0020 | 3.4598 | 9.3700 | AID1452239 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |
Research
Studies (4)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 21.50
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| Metric | This Compound (vs All) |
|---|
| Research Demand Index | 21.50 (24.57) | | Research Supply Index | 2.08 (2.92) | | Research Growth Index | 4.51 (4.65) | | Search Engine Demand Index | 15.26 (26.88) | | Search Engine Supply Index | 2.00 (0.95) |
| |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 7 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |