Dibenzo(a,h)pyrene (DBP) is a potent polycyclic aromatic hydrocarbon (PAH) that has been extensively studied due to its significant carcinogenic properties. It is commonly found in environmental samples, particularly in coal tar, diesel exhaust, and cigarette smoke. DBP is formed through incomplete combustion of organic materials and can be absorbed through inhalation, ingestion, or skin contact. Its potent carcinogenicity is attributed to its ability to bind to DNA, leading to mutations and ultimately cancer development. Research on DBP focuses on understanding its mechanisms of action, its environmental distribution and fate, and developing strategies for its prevention and remediation. While DBP is not commercially synthesized, its presence as a contaminant in various industrial processes and environmental samples makes it a critical subject of study in toxicology and environmental science.'
dibenzo(a,h)pyrene: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 9108 |
| CHEBI ID | 82313 |
| MeSH ID | M0098216 |
| Synonym |
|---|
| ccris 213 |
| 3,4,8,9-dibenzopyrene |
| einecs 205-878-0 |
| db(a,h)p |
| hsdb 4028 |
| dibenzo(b,def)chrysene |
| 3,4,8,9-dibenzpyrene |
| brn 2054067 |
| dibenzo(a,h)pyrene |
| 1,2,6,7-dibenzopyrene |
| 3,4:8,9-dibenzopyrene |
| dibenzo[b,def]chrysene |
| 189-64-0 |
| 3,4:8,9-dibenzpyrene |
| D1005 |
| dibenzo[a,h]pyrene |
| C19222 |
| AKOS024319583 |
| xr5r3v8bjk , |
| 4-05-00-02802 (beilstein handbook reference) |
| unii-xr5r3v8bjk |
| FT-0631860 |
| dibenzo(a,h)pyrene [iarc] |
| dibenzo(a,h)pyrene [hsdb] |
| CHEBI:82313 |
| DTXSID4059752 |
| 2-amino-3,5-pyridinedicarboxylicacid |
| RXUSYFJGDZFVND-UHFFFAOYSA-N |
| 1,2,6,7-dibenzpyrene |
| dibenzo[a,h]pyrene, bcr(r) certified reference material |
| mfcd00039579 |
| hexacyclo[10.10.2.0(2),?.0?,(2)(3).0(1)(3),(1)?.0(2)?,(2)?]tetracosa-1,3,5,7,9,11,13(18),14,16,19,21,23-dodecaene |
| AS-57745 |
| dibenzo[a,h]pyrene, vial of 10 mg, analytical standard |
| dibenzo[b,def]chrysene; 3,4:8,9-dibenzopyrene; dibenzo[a,h]pyrene |
| dibenzo[a,h]pyrene 10 microg/ml in cyclohexane |
| dibenzo[a,h]pyrene 10 microg/ml in acetonitrile |
| J-012235 |
| dibenzo[c,pqr]tetraphene |
| Q26841300 |
| hexacyclo[10.10.2.02,7.09,23.013,18.020,24]tetracosa-1(23),2,4,6,8,10,12(24),13,15,17,19,21-dodecaene |
| D89758 |
| 3,4,8,9-dibenzpyren |
| dibenzo (a,h) pyrene (purity) |
| CS-0324091 |
| Class | Description |
|---|---|
| ortho- and peri-fused polycyclic arene | |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 4 (44.44) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (19.43) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 10 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||