diamminediaqua platinum(ii)

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

diamminediaqua platinum(II): RN given refers to (SP-4-1)-isomer; hydrolysis product of cisplatin [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	159884
MeSH ID	M0105793

Synonyms (13)

Synonym
platinum(2+), diamminediaqua-, (sp-4-1)-
platinum(2+), diamminediaqua-, ion, trans-
cis-diaquodiammineplatinum(ii)
diamminediaqua platinum(ii)
platinum(2+), diamminediaqua-, (sp-4-2)-
cis-diamminediaquaplatinum(2+) ion
trans-diaquodiammineplatinum(ii)
cis-diamminediaquaplatinum(2+)
platinum(2+), diamminediaqua-, ion, cis-
trans-diamminediaquaplatinum(2+)
20115-65-5
20115-64-4
azane;platinum(2+);dihydrate

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (11)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	6 (54.55)	18.7374
1990's	3 (27.27)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (18.18)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.72

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	11.72 (24.57)
Research Supply Index	2.56 (2.92)
Research Growth Index	4.29 (4.65)
Search Engine Demand Index	0.00 (26.88)
Search Engine Supply Index	0.00 (0.95)

This Compound (11.72)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	1 (8.33%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	11 (91.67%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
uracil 2,4-dihydroxypyrimidine: a urinary biomarker for bipolar disorder	2.05	1	pyrimidine nucleobase; pyrimidone	allergen; Daphnia magna metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; prodrug; Saccharomyces cerevisiae metabolite
platinum Platinum: A heavy, soft, whitish metal, resembling tin, with atomic number 78, atomic weight 195.084, symbol Pt. It is used in manufacturing equipment for laboratory and industrial use. It occurs as a black powder (platinum black) and as a spongy substance (spongy platinum) and may have been known in Pliny's time as alutiae.	3.07	1	elemental platinum; nickel group element atom; platinum group metal atom
zinc sulfate Zinc Sulfate: A compound given in the treatment of conditions associated with zinc deficiency such as acrodermatitis enteropathica. Externally, zinc sulfate is used as an astringent in lotions and eye drops. (Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Englewood, CO, 1995). zinc sulfate : A metal sulfate compound having zinc(2+) as the counterion.	1.97	1	metal sulfate; zinc molecular entity	fertilizer
muramidase Muramidase: A basic enzyme that is present in saliva, tears, egg white, and many animal fluids. It functions as an antibacterial agent. The enzyme catalyzes the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrin. EC 3.2.1.17.	2.07	1
guanosine monophosphate Guanosine Monophosphate: A guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature.. guanosine 5'-monophosphate : A purine ribonucleoside 5'-monophosphate having guanine as the nucleobase.	1.96	1	guanosine 5'-phosphate; purine ribonucleoside 5'-monophosphate	biomarker; Escherichia coli metabolite; metabolite; mouse metabolite
guanosine ribonucleoside : Any nucleoside where the sugar component is D-ribose.	1.96	1	guanosines; purines D-ribonucleoside	fundamental metabolite
deoxydiguanosine diphosphosphate 5'-d(pGpG)-3' : A single-stranded DNA oligonucleotide comprising two 2'-deoxyguanosine residues connected by a 3'->5 linkage and with a phosphoric group at the 5'-terminus.	1.96	1	5'-phospho-(3'->5')-dinucleotide; single-stranded DNA oligonucleotide	Mycoplasma genitalium metabolite
guanylyl-(3'-5')-guanosine [no description available]	1.96	1	nucleoside analogue; purines
deoxyguanylyl-(3'-5')-guanosine deoxyguanylyl-(3'-5')-guanosine: RN given refers to parent cpd	1.96	1
metallothionein Metallothionein: A low-molecular-weight (approx. 10 kD) protein occurring in the cytoplasm of kidney cortex and liver. It is rich in cysteinyl residues and contains no aromatic amino acids. Metallothionein shows high affinity for bivalent heavy metals.	1.97	1

Condition	Relationship Strength	Studies
Adenocarcinoma Of Kidney [description not available]	1.98	1
Cancer of Kidney [description not available]	1.98	1
Carcinoma, Renal Cell A heterogeneous group of sporadic or hereditary carcinoma derived from cells of the KIDNEYS. There are several subtypes including the clear cells, the papillary, the chromophobe, the collecting duct, the spindle cells (sarcomatoid), or mixed cell-type carcinoma.	1.98	1
Kidney Neoplasms Tumors or cancers of the KIDNEY.	1.98	1
Carcinoma, Epidermoid [description not available]	1.99	1
Cancer of Head [description not available]	1.99	1
Carcinoma, Squamous Cell A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)	1.99	1
Head and Neck Neoplasms Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651)	1.99	1
Experimental Radiation Injuries [description not available]	2.89	1
Experimental Leukemia [description not available]	1.96	1
Osteogenic Sarcoma [description not available]	1.96	1
Dysembryoma [description not available]	1.96	1
Osteosarcoma A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed)	1.96	1
Teratoma A true neoplasm composed of a number of different types of tissue, none of which is native to the area in which it occurs. It is composed of tissues that are derived from three germinal layers, the endoderm, mesoderm, and ectoderm. They are classified histologically as mature (benign) or immature (malignant). (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1642)	1.96	1
Germinoblastoma [description not available]	2.37	2
Lymphoma A general term for various neoplastic diseases of the lymphoid tissue.	2.37	2

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