Compounds > di-n-propyl trisulfide
Page last updated: 2024-12-06

di-n-propyl trisulfide

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Di-n-propyl trisulfide is an organosulfur compound with the formula (CH3CH2CH2S)3. It is a colorless liquid with a strong, unpleasant odor. Di-n-propyl trisulfide is a component of garlic oil and other plant oils. It is also found in some fermented foods, such as cheese. Di-n-propyl trisulfide has been shown to have a variety of biological activities, including antimicrobial, antifungal, and antioxidant properties. It is also a potent inhibitor of platelet aggregation. Di-n-propyl trisulfide is being studied for its potential therapeutic applications, such as the treatment of cancer and cardiovascular disease. The compound has been found to be effective in reducing the growth of certain types of cancer cells. It is also thought to have the potential to protect the heart from damage. The synthesis of di-n-propyl trisulfide involves the reaction of n-propyl mercaptan with sulfur. The compound can be produced by a variety of methods, but most often involves the use of a catalyst. Di-n-propyl trisulfide is studied for its potential use in medicine and agriculture. For example, it is being investigated for its potential to inhibit the growth of bacteria and fungi. It is also being studied for its potential to reduce the damage caused by oxidative stress. Di-n-propyl trisulfide is a promising molecule with a variety of potential applications.'

di-n-propyl trisulfide: antioxidant found in Allium species; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

FloraRankFlora DefinitionFamilyFamily Definition
AlliumgenusA genus of the plant family Amaryllidaceae. Many produce pungent, often bacteriostatic and physiologically active compounds and are used as VEGETABLES; CONDIMENTS; and medicament, the latter in traditional medicine.[MeSH]AmaryllidaceaeA family of herbaceous plants with bulbs or rhizomes in the order Asparagales.[MeSH]

Cross-References

ID SourceID
PubMed CID22383
CHEMBL ID3222023
CHEBI ID173865
SCHEMBL ID564543
MeSH IDM0502183

Synonyms (41)

Synonym
6028-61-1
1-(propyltrisulanyl)propane
CHEBI:173865
propyl trisulfide
trisulfide, dipropyl
brn 1736293
ccris 3264
dipropyl trisulfide
einecs 227-903-4
fema no. 3276
dipropyl trisulphide
1-(propyltrisulfanyl)propane
A832669
1-(propyltrisulfanyl)propane;dipropyl trisulfide
AKOS006272331
1-propylsulfanyldisulfanyl-propane
di-n-propyl trisulfide
u4529nm2c1 ,
unii-u4529nm2c1
FT-0625299
fema no. 4042, dipropyl-
dipropyl trisulfide [fhfi]
SCHEMBL564543
CHEMBL3222023
DTXSID5047401
1,3-dipropyltrisulfane
GAZXPZNJTZIGBO-UHFFFAOYSA-N
1,3-dipropyltrisulfane #
dipropyltrisulfane
dipropyl trisulfide, aldrichcpr
dipropyl trisulfide, >=95%, fg
4,5,6-trithianonane
fema 3276
mfcd00040074
AS-14722
Q27290661
D95313
2-isopropoxy-5-(trifluoromethoxy)phenylboronicacid
nsc798036
nsc-798036
D5750
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
organic trisulfideAn organosulfur compound with structure Compounds of structure R(1)SSSR(2) in which R(1) and R(2) are organic groups.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (42.86)29.6817
2010's3 (42.86)24.3611
2020's1 (14.29)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.36

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.36 (24.57)
Research Supply Index2.08 (2.92)
Research Growth Index4.44 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.36)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
n-propyl disulfide
n-propyl disulfide: major flavor component of onions; non-nitrogenous, pungent volatile oil. dipropyl disulfide : An organic disulfide where the alkyl groups specified are propyl. It is a component of the essential oils obtained from Allium.		2.4420organic disulfideplant metabolite
diallyl trisulfide
[no description available]		2.7730organic trisulfideanti-inflammatory agent;
antilipemic drug;
antineoplastic agent;
antioxidant;
antiprotozoal drug;
apoptosis inducer;
estrogen receptor antagonist;
insecticide;
platelet aggregation inhibitor;
vasodilator agent
dimethyl trisulfide
[no description available]		2.4620organic trisulfide
buthionine sulfoximine
Buthionine Sulfoximine: A synthetic amino acid that depletes glutathione by irreversibly inhibiting gamma-glutamylcysteine synthetase. Inhibition of this enzyme is a critical step in glutathione biosynthesis. It has been shown to inhibit the proliferative response in human T-lymphocytes and inhibit macrophage activation. (J Biol Chem 1995;270(33):1945-7). 2-amino-4-(S-butylsulfonimidoyl)butanoic acid : A non-proteinogenic alpha-amino acid that is homocysteine in which the thiol group carries an oxo, imino and butyl groups.. S-butyl-DL-homocysteine (S,R)-sulfoximine : A sulfoximide that is the sulfoximine derivative of an analogue of DL-methionine in which the S-methyl group is replaced by S-butyl.		2.0410diastereoisomeric mixture;
homocysteines;
non-proteinogenic alpha-amino acid;
sulfoximide		EC 6.3.2.2 (glutamate--cysteine ligase) inhibitor;
ferroptosis inducer
alkenes
[no description available]		2.0410
methylallyl trisulfide
methylallyl trisulfide: platelet aggregation inhibitor in garlic		2.4620
allyl methyl disulfide
allyl methyl disulfide: structure given in first source. allyl methyl disulfide : An organic disulfide having allyl and methyl as the two organic groups.		2.0610organic disulfideplant metabolite;
volatile oil component
sulfur
Sulfur: An element that is a member of the chalcogen family. It has an atomic symbol S, atomic number 16, and atomic weight [32.059; 32.076]. It is found in the amino acids cysteine and methionine.		2.0510chalcogen;
nonmetal atom		macronutrient
cysteine
Cysteine: A thiol-containing non-essential amino acid that is oxidized to form CYSTINE.. L-cysteinium : The L-enantiomer of cysteinium.. cysteine : A sulfur-containing amino acid that is propanoic acid with an amino group at position 2 and a sulfanyl group at position 3.		2.4420cysteiniumfundamental metabolite
phosphatidylcholines
Phosphatidylcholines: Derivatives of PHOSPHATIDIC ACIDS in which the phosphoric acid is bound in ester linkage to a CHOLINE moiety.		2.03101,2-diacyl-sn-glycero-3-phosphocholine
ConditionIndicatedRelationship StrengthStudiesTrials
Adenocarcinoma, Basal Cell
[description not available]		02.0410
Cancer of Colon
[description not available]		02.0410
Adenocarcinoma
A malignant epithelial tumor with a glandular organization.		02.0410
Colonic Neoplasms
Tumors or cancer of the COLON.		02.0410
Aging
The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.		02.0310