di-2-pyridyl ketone isonicotinoyl hydrazone: a chelating agent; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 10447697 |
| CHEMBL ID | 238648 |
| SCHEMBL ID | 1025581 |
| MeSH ID | M0499522 |
| Synonym |
|---|
| n-(dipyridin-2-ylmethylideneamino)pyridine-4-carboxamide |
| hdpkihz |
| di-2-pyridyl ketone isonicotinoylhydrazone |
| n-[bis(2-pyridyl)methyleneamino]pyridine-4-carboxamide |
| di-2-pyridylketone isonicotinoyl hydrazone |
| di-2-pyridyl ketoneisonicotinoylhydrazone |
| CHEMBL238648 |
| di-2-pyridylketone isonicotinoylhydrazone |
| SCHEMBL1025581 |
| bis(2-pyridyl)methanone isonicotinoyl hydrazone |
| di-2-pyridyl ketone isonicotinoyl hydrazone |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID312544 | Antiproliferative activity against human SK-MN-C cells by MTT assay | 2008 | Journal of medicinal chemistry, Jan-24, Volume: 51, Issue:2 | Structure-activity relationships of novel iron chelators for the treatment of iron overload disease: the methyl pyrazinylketone isonicotinoyl hydrazone series. |
| AID478786 | Cytotoxicity against mouse J774 cells after 24 hrs by resazurin assay | 2010 | European journal of medicinal chemistry, May, Volume: 45, Issue:5 | Thiosemicarbazones, semicarbazones, dithiocarbazates and hydrazide/hydrazones: anti-Mycobacterium tuberculosis activity and cytotoxicity. |
| AID478787 | Selectivity index, ratio of IC50 for mouse J774 cells to MIC for Mycobacterium tuberculosis H37Rv | 2010 | European journal of medicinal chemistry, May, Volume: 45, Issue:5 | Thiosemicarbazones, semicarbazones, dithiocarbazates and hydrazide/hydrazones: anti-Mycobacterium tuberculosis activity and cytotoxicity. |
| AID478785 | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv after 7 days by resazurine microtiter assay | 2010 | European journal of medicinal chemistry, May, Volume: 45, Issue:5 | Thiosemicarbazones, semicarbazones, dithiocarbazates and hydrazide/hydrazones: anti-Mycobacterium tuberculosis activity and cytotoxicity. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.63) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||