di-(2-amino-5-nitrothiazole)dichloroplatinum(ii) profile

Cross-References

ID Source	ID
PubMed CID	3081556
MeSH ID	M0148892

Synonyms (7)

Synonym
di-(2-amino-5-nitrothiazole)dichloroplatinum(ii)
platinum, dichlorobis(5-nitro-2-thiazolamine-n2)-, (sp-4-1)-
69433-99-4
pt-plant
platinum(2+) chloride--5-nitro-1,3-thiazol-2(3h)-imine (1/2/2)
DTXSID00989285
5-nitro-1,3-thiazol-2-amine;platinum(2+);dichloride

Research Excerpts

Toxicity

Excerpt	Reference	Relevance
" Plant was also more toxic to both normally oxygenated and hypoxic cells at elevated temperatures at normal pH."	( Effect of hypoxia and acidosis on the cytotoxicity of four platinum complexes at normal and hyperthermic temperatures. Collins, LS; Herman, TS; Teicher, BA, 1988)	0.27

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	5 (83.33)	18.7374
1990's	1 (16.67)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.35

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	12.35 (24.57)
Research Supply Index	1.95 (2.92)
Research Growth Index	4.29 (4.65)
Search Engine Demand Index	0.00 (26.88)
Search Engine Supply Index	0.00 (0.95)

This Compound (12.35)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	6 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes
nitrates Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.	1.97	1	monovalent inorganic anion; nitrogen oxoanion; reactive nitrogen species
chloroterpyridineplatinum(ii) [no description available]	1.97	1
nadp [no description available]	1.97	1

Condition	Relationship Strength	Studies
Carcinoma, Epidermoid [description not available]	1.97	1
Cancer of Head [description not available]	1.97	1
Carcinoma, Squamous Cell A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)	1.97	1
Head and Neck Neoplasms Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651)	1.97	1
Farmer's Lung A form of alveolitis or pneumonitis due to an acquired hypersensitivity to inhaled antigens associated with farm environment. Antigens in the farm dust are commonly from bacteria actinomycetes (SACCHAROPOLYSPORA and THERMOACTINOMYCES), fungi, and animal proteins in the soil, straw, crops, pelts, serum, and excreta.	1.97	1

di-(2-amino-5-nitrothiazole)dichloroplatinum(ii)