| Substance | Relationship Strength | Studies | Trials | Classes | Roles |
|---|
colchicine
(S)-colchicine : A colchicine that has (S)-configuration. It is a secondary metabolite, has anti-inflammatory properties and is used to treat gout, crystal-induced joint inflammation, familial Mediterranean fever, and many other conditions. | 9.18 | 5 | 0 | alkaloid;
colchicine | anti-inflammatory agent;
gout suppressant;
mutagen |
dithionitrobenzoic acid
Dithionitrobenzoic Acid: A standard reagent for the determination of reactive sulfhydryl groups by absorbance measurements. It is used primarily for the determination of sulfhydryl and disulfide groups in proteins. The color produced is due to the formation of a thio anion, 3-carboxyl-4-nitrothiophenolate.. dithionitrobenzoic acid : An organic disulfide that results from the formal oxidative dimerisation of 2-nitro-5-thiobenzoic acid. An indicator used to quantify the number or concentration of thiol groups. | 2 | 1 | 0 | nitrobenzoic acid;
organic disulfide | indicator |
tropolone
Tropolone: A seven-membered aromatic ring compound. It is structurally related to a number of naturally occurring antifungal compounds (ANTIFUNGAL AGENTS).. tropolone : A cyclic ketone that is cyclohepta-2,4,6-trien-1-one substituted by a hydroxy group at position 2. It is a toxin produced by the agricultural pathogen Burkholderia plantarii. | 2.66 | 3 | 0 | alpha-hydroxy ketone;
cyclic ketone;
enol | bacterial metabolite;
fungicide;
toxin |
thiocholchicine
thiocholchicine: RN refers to (S)-isomer | 3.35 | 1 | 0 | | |
n-methylcolchiceinamide, (s)-isomer
[no description available] | 3.35 | 1 | 0 | | |
colchicenamide
colchicenamide: RN given refers to (S)-isomer; structure given in first source | 3.35 | 1 | 0 | | |
paclitaxel
Taxus: Genus of coniferous yew trees or shrubs, several species of which have medicinal uses. Notable is the Pacific yew, Taxus brevifolia, which is used to make the anti-neoplastic drug taxol (PACLITAXEL). | 1.96 | 1 | 0 | taxane diterpenoid;
tetracyclic diterpenoid | antineoplastic agent;
human metabolite;
metabolite;
microtubule-stabilising agent |
2-methoxy-5-(2',3',4'-trimethoxyphenyl)tropone
2-methoxy-5-(2',3',4'-trimethoxyphenyl)tropone: structure given in first source | 2.66 | 3 | 0 | | |
5,5'-bis(8-(phenylamino)-1-naphthalenesulfonate)
[no description available] | 2 | 1 | 0 | | |
demecolcine
Demecolcine: An alkaloid isolated from Colchicum autumnale L. and used as an antineoplastic.. (-)-demecolcine : A secondary amino compound that is (S)-colchicine in which the N-acetyl group is replaced by an N-methyl group. Isolable from the autumn crocus, Colchicum autumnale, it is less toxic than colchicine and is used as an antineoplastic. | 1.96 | 1 | 0 | alkaloid;
secondary amino compound | antineoplastic agent;
microtubule-destabilising agent |
n-acetylcolchinol
N-acetylcolchinol: structure | 3.35 | 1 | 0 | | |
fosbretabulin
[no description available] | 3.35 | 1 | 0 | stilbenoid | |
cysteine
Cysteine: A thiol-containing non-essential amino acid that is oxidized to form CYSTINE.. L-cysteinium : The L-enantiomer of cysteinium.. cysteine : A sulfur-containing amino acid that is propanoic acid with an amino group at position 2 and a sulfanyl group at position 3. | 2 | 1 | 0 | cysteinium | fundamental metabolite |