Page last updated: 2024-11-13

deoxynivalenol-3-glucoside

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

deoxynivalenol-3-glucoside: a major conjugate of deoxynivalenol in beer and some brewing intermediates [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID71312510
CHEBI ID168268
MeSH IDM0537407

Synonyms (19)

Synonym
(1r,2r,3s,7r,9r,10r,12s)-3-hydroxy-2-(hydroxymethyl)-1,5-dimethyl-10-[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyspiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2'-oxirane]-4-one
131180-21-7
deoxynivalenol 3-glucoside
CHEBI:168268
hki01r84m9 ,
deoxynivalenol-3beta-glucopyranoside
unii-hki01r84m9
deoxynivalenol-3-o-glucoside
trichothec-9-en-8-one, 12,13-epoxy-3-(beta-d-glucopyranosyloxy)-7,15-dihydroxy-, (3alpha,7alpha)-
vomitoxin 3-glucoside
trichothec-9-en-8-one, 12,13-epoxy-3-(.beta.-d-glucopyranosyloxy)-7,15-dihydroxy-, (3.alpha.,7.alpha.)-
deoxynivalenol-3-glucoside
(3alpha,7beta,12epsilon)-7,15-dihydroxy-8-oxo-12,13-epoxytrichothec-9-en-3-yl beta-d-glucopyranoside
DTXSID10891865
Q27279973
deoxynivalenol-3-glucoside 50 microg/ml in acetonitrile
deoxynivalenol-3-|a-d-glucoside
CS-0693703
HY-N11678

Research Excerpts

Bioavailability

ExcerptReferenceRelevance
" Compared to DON, the oral bioavailability of D3G and its metabolites seems to be reduced by a factor of up to 2, approximately."( Metabolism of the masked mycotoxin deoxynivalenol-3-glucoside in pigs.
Adam, G; Berthiller, F; Hennig-Pauka, I; Moll, WD; Nagl, V; Schwartz-Zimmermann, HE; Woechtl, B, 2014
)
0.68
" Furthermore, the absolute oral bioavailability of DON3G in broiler chickens was low (3."( In vivo contribution of deoxynivalenol-3-β-D-glucoside to deoxynivalenol exposure in broiler chickens and pigs: oral bioavailability, hydrolysis and toxicokinetics.
Adam, G; Berthiller, F; Broekaert, N; Croubels, S; De Boevre, M; De Saeger, S; Devreese, M; Malachová, A; Michlmayr, H; Schauvliege, S; van Bergen, T; Vanhaecke, L; Vermeulen, A, 2017
)
0.46

Dosage Studied

ExcerptRelevanceReference
" Mycotoxins were dosed at varying concentrations to 11."( The lager yeast Saccharomyces pastorianus removes and transforms Fusarium trichothecene mycotoxins during fermentation of brewer's wort.
Gibson, B; Han, L; Jestoi, M; Laitila, A; Nathanail, AV; Ollilainen, V; Peltonen, K, 2016
)
0.43
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
trichotheceneAny one of a large family of chemically related mycotoxins with a structure based on a sesquiterpene skeleton. The most important structural features causing the biological activities of trichothecenes are a 12,13-epoxy ring, the presence of hydroxy or acetyl groups at appropriate positions on the trichothecene nucleus and the structure and position of the side-chain.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (65)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (1.54)29.6817
2010's53 (81.54)24.3611
2020's11 (16.92)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 21.67

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index21.67 (24.57)
Research Supply Index4.19 (2.92)
Research Growth Index6.56 (4.65)
Search Engine Demand Index18.60 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (21.67)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews2 (3.08%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other63 (96.92%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]