Page last updated: 2024-12-07

delta(1)-pyrroline

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Delta(1)-pyrroline, also known as 1-pyrroline, is a heterocyclic compound with a five-membered ring containing one nitrogen atom and one double bond. It is a colorless, volatile liquid with a pungent odor. Delta(1)-pyrroline is a reactive intermediate in the Maillard reaction, a complex chemical reaction that occurs when sugars and amino acids are heated. This reaction is responsible for the browning of food and the development of flavor. Delta(1)-pyrroline is also a precursor to several other heterocyclic compounds, including pyrrole and pyrazole. The compound is known to be unstable and can readily polymerize. It is often generated in situ and used immediately. Delta(1)-pyrroline is also found in various natural products, including the aroma compounds of roasted coffee, cooked meat, and cheese. Its synthesis typically involves the reduction of pyrrole or the cyclization of an amino acid. Research on delta(1)-pyrroline focuses on its role in flavor chemistry, food processing, and as a precursor to other important compounds.'

Cross-References

ID SourceID
PubMed CID79803
CHEBI ID19092
MeSH IDM0085061

Synonyms (17)

Synonym
unii-2sk2i7766o
einecs 227-230-6
2sk2i7766o ,
CHEBI:19092 ,
1-pyrroline
delta(1)-pyrroline
5724-81-2
2h-pyrrole, 3,4-dihydro-
inchi=1/c4h7n/c1-2-4-5-3-1/h3h,1-2,4h
3,4-dihydro-2h-pyrrole
1-pyrroline [fhfi]
.delta.1-pyrroline
isopyrroline
fema no. 3898
2h-pyrrolenine, 3,4-dihydro-
DTXSID10863608
Q161680
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (2)

ClassDescription
pyrrolineAny organic heteromonocyclic compound with a structure based on a dihydropyrrole.
imineCompounds having the structure RN=CR2 (R = H, hydrocarbyl). Thus analogues of aldehydes or ketones, having NR doubly bonded to carbon; aldimines have the structure RCH=NR, ketimines have the structure R'2C=NR (where R' is not H). Imines include azomethines and Schiff bases. Imine is used as a suffix in systematic nomenclature to denote the C=NH group excluding the carbon atom.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Pathways (2)

PathwayProteinsCompounds
Beta-alanine biosynthesis04
Beta-alanine biosynthesis I312

Research

Studies (12)

TimeframeStudies, This Drug (%)All Drugs %
pre-19909 (75.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (16.67)24.3611
2020's1 (8.33)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 20.76

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index20.76 (24.57)
Research Supply Index2.64 (2.92)
Research Growth Index4.32 (4.65)
Search Engine Demand Index15.26 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (20.76)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other13 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]